What You Do in High School Matters: The Effects of High School GPA on Educational Attainment and Labor Market Earnings in Adulthood

Using abstracted grades and other data from Add Health, we investigate the effects of cumulative high school GPA on educational attainment and labor market earnings among a sample of young adults (ages 24-34). We estimate several models with an extensive list of control variables and high school fixed effects. Results consistently show that high school GPA is a positive and statistically significant predictor of educational attainment and earnings in adulthood. Moreover, the effects are large and economically important for each gender. Interesting and somewhat unexpected findings emerge for race. Various sensitivity tests support the stability of the core findings.High school grades; Educational attainment; Earnings; Panel data

Thermal Performance Data Services (TPDS)

Initiated as a NASA Engineering and Safety Center (NESC) assessment in 2009, the Thermal Performance Database (TPDB) was a response to the need for a centralized thermal performance data archive. The assessment was renamed Thermal Performance Data Services (TPDS) in 2012; the undertaking has had two fronts of activity: the development of a repository software application and the collection of historical thermal performance data sets from dispersed sources within the thermal performance community. This assessment has delivered a foundational tool on which additional features should be built to increase efficiency, expand the protection of critical Agency investments, and provide new discipline-advancing work opportunities. This report contains the information from the assessment

Fibronectin and Cyclic Strain Improve Cardiac Progenitor Cell Regenerative Potential In Vitro.

Cardiac progenitor cells (CPCs) have rapidly advanced to clinical trials, yet little is known regarding their interaction with the microenvironment. Signaling cues present in the microenvironment change with development and disease. This work aims to assess the influence of two distinct signaling moieties on CPCs: cyclic biaxial strain and extracellular matrix. We evaluate four endpoints for improving CPC therapy: paracrine signaling, proliferation, connexin43 expression, and alignment. Vascular endothelial growth factor A (about 900 pg/mL) was secreted by CPCs cultured on fibronectin and collagen I. The application of mechanical strain increased vascular endothelial growth factor A secretion 2-4-fold for CPCs cultured on poly-L-lysine, laminin, or a naturally derived cardiac extracellular matrix. CPC proliferation was at least 25% higher on fibronectin than that on other matrices, especially for lower strain magnitudes. At 5% strain, connexin43 expression was highest on fibronectin. With increasing strain magnitude, connexin43 expression decreased by as much as 60% in CPCs cultured on collagen I and a naturally derived cardiac extracellular matrix. Cyclic mechanical strain induced the strongest CPC alignment when cultured on fibronectin or collagen I. This study demonstrates that culturing CPCs on fibronectin with 5% strain magnitude is optimal for their vascular endothelial growth factor A secretion, proliferation, connexin43 expression, and alignment

The NASA/IPAC Teacher Archive Research Program (NITARP)

NITARP, the NASA/IPAC Teacher Archive Research Program, partners small groups of predominantly high school educators with research astronomers for a year-long research project. This paper presents a summary of how NITARP works and the lessons learned over the last 13 years. The program lasts a calendar year, January to January, and involves three ~week-long trips: to the American Astronomical Society (AAS) winter meeting, to Caltech in the summer (with students), and back to a winter AAS meeting (with students) to present their results. Because NITARP has been running since 2009, and its predecessor ran from 2005-2008, there have been many lessons learned over the last 13 years that have informed the development of the program. The most critical is that scientists must see their work with the educators on their team as a partnership of equals who have specialized in different professions. NITARP teams appear to function most efficiently with approximately 5 people: a mentor astronomer, a mentor teacher (who has been through the program before), and 3 new educators. Educators are asked to step into the role of learner and develop their question-asking skills as they work to develop an understanding of a subject in which they will not have command of all the information and processes needed. Critical to the success of each team is the development of communication skills and fluid plan of action to keep the lines of communication open. This program has allowed more than 100 educators to present more than 60 total science posters at the AAS

Diagnosis of childhood tuberculosis and host RNA expression in Africa

Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV