688 research outputs found

    Social Service Workers Working Social Policy: A Qualitative Study of Social Policy, Political Culture, and Organizations

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    In 13 semi-structured, face-to-face interviews at a social service organization, workers were asked to discuss the problems and challenges that made their day-to-day jobs difficult. Most workers identified problems and challenges at the client-level, while secondarily discussing organizational and societal challenges. The findings in the research speak to Michael Lipsky\u27s \u27Street-Level Bureaucracy\u27 in that the people that administer social policy on a day-to-day basis with their clients identify the most difficulties in carrying out their organizational objectives of changing their clients not husbanding material resources

    Understanding the Critical Ingredients for Facilitating Consumer Change in Housing First Programming: A Case Study Approach

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    Housing First is a form of permanent supportive housing for chronically homeless consumers with mental health and substance abuse issues. In light of the model’s growing popularity and wide diffusion, researchers and policy makers have identified a need to better understand its critical ingredients and the processes through which they affect consumer outcomes. Researchers used a bottom-up approach to understand the critical ingredients of Housing First within community-based programs. Interviews and focus groups were conducted with 60 informants (staff and consumers) across 4 “successful” Housing First programs. Qualitative analysis demonstrated six program ingredients to be essential: (1) a low-threshold admissions policy, (2) harm reduction, (3) eviction prevention, (4) reduced service requirements, (5) separation of housing and services, and (6) consumer education

    The increasing diversity of functions attributed to the SAFB family of RNA/DNA binding proteins

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    RNA-binding proteins play a central role in cellular metabolism by orchestrating the complex interactions of coding, structural and regulatory RNA species. The SAFB (scaffold attachment factor B) proteins (SAFB1, SAFB2 and SAFB-like transcriptional modulator, SLTM), which are highly conserved evolutionarily, were first identified on the basis of their ability to bind scaffold attachment region DNA elements, but attention has subsequently shifted to their RNA-binding and protein–protein interactions. Initial studies identified the involvement of these proteins in the cellular stress response and other aspects of gene regulation. More recently, the multifunctional capabilities of SAFB proteins have shown that they play crucial roles in DNA repair, processing of mRNA and regulatory RNA, as well as in interaction with chromatin-modifying complexes. With the advent of new techniques for identifying RNA-binding sites, enumeration of individual RNA targets has now begun. This review aims to summarise what is currently known about the functions of SAFB proteins.</jats:p

    Distributed Social Multi-Agent Negotiation Framework For Incomplete Information Games

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    In this paper, we propose a social negotiation system in which agents can communicate and interact with each other socially throughout a Sheriff of Nottingham game. We address issues with the number of options available while negotiating, particularly when bluffing is involved. Experiments are proposed that would allow us to validate how closely this framework mirrors real social interaction in the game, and the possibility of generalising multi-agent negotiation beyond this framework is raised

    Pathology of Macular Foveoschisis Associated with Degenerative Myopia

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    This is a clinicopathological paper on the histologic findings in myopia-associated macular foveoschisis. The findings on ophthalmic pathological study of a 73-year-old woman with high myopia are reviewed. Multiple retinoschisis cavities involving both the macula and retinal periphery were disclosed. Our paper offers tissue evidence and supports recent ocular coherence tomography reports of eyes with high myopia and associated macular foveoschisis

    Enhancing Programming Learning with AI-Generated Contextual Examples in Digital Creativity

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    Programming concepts are challenging for new learners to grasp. This is especially the case for creative arts students who are typically unfamiliar with computing concepts and the associated vocabulary at enrolment. One means to enhance their learning is to situate examples in a relatable disciplinary context and to adapt learning material accordingly. However, this can be onerous and time-consuming to prepare; particularly in diverse modules that include learners from a wide range of different disciplines. This position paper proposes the use of large language models to automate tailoring the content of adaptive hypermedia systems such as personalised wikis. These tools can re-situate examples into many contexts that learners are already familiar with. A pilot study using ChatGPT (using GPT-4) for a first-stage undergraduate Digital Creativity module is presented. Generative artificial intelligence changes the examples used to illustrate programming concepts according to a student’s course. These examples are evaluated by academic colleagues drawn from the different course teams to rate the generated analogies. Initial results are encouraging, illustrating a high degree of face validity. Further work in 2023-24 will evaluate whether this improves learning during the module

    An early chondrichthyan and the evolutionary assembly of a shark body plan

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    Although relationships among the major groups of living gnathostomes are well established, the relatedness of early jawed vertebrates to modern clades is intensely debated. Here, we provide a new description of Gladbachus , a Middle Devonian (Givetian approx. 385-million-year-old) stem chondrichthyan from Germany, and one of the very few early chondrichthyans in which substantial portions of the endoskeleton are preserved. Tomographic and histological techniques reveal new details of the gill skeleton, hyoid arch and jaws, neurocranium, cartilage, scales and teeth. Despite many features resembling placoderm or osteichthyan conditions, phylogenetic analysis confirms Gladbachus as a stem chondrichthyan and corroborates hypotheses that all acanthodians are stem chondrichthyans. The unfamiliar character combination displayed by Gladbachus , alongside conditions observed in acanthodians, implies that pre-Devonian stem chondrichthyans are severely under-sampled and strongly supports indications from isolated scales that the gnathostome crown group originated at the latest by the early Silurian (approx. 440 Ma). Moreover, phylogenetic results highlight the likely convergent evolution of conventional chondrichthyan conditions among earliest members of this primary gnathostome division, while skeletal morphology points towards the likely suspension feeding habits of Gladbachus , suggesting a functional origin of the gill slit condition characteristic of the vast majority of living and fossil chondrichthyans. </jats:p
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