120 research outputs found

    Discrete One-dimensional Models for the Electromomentum Coupling

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    Willis dynamic homogenization theory revealed that the effective linear momentum of elastic composites is coupled to their effective strain. % This result, which is partially due to asymmetry at the subwavelength scale, implies that spatially-uniform but time-varying stress can induce temporal variations in the macroscopically observable momentum. Recent generalization of Willis' dynamic homogenization theory to the case of piezoelectric composites further revealed that their effective linear momentum is also coupled to the effective electric field. Here, we introduce the simplest possible model -- a one-dimensional discrete model -- that exhibits this so-called electromomentum coupling in subwavelength composites. We utilize our model to elucidate the physical origins of this phenomenon, illustrate its mechanism, and identify local resonances which lead to elevated Willis- and electromomentum coupling in narrow frequency bands. The results provide intuitive guidelines for the design of this coupling in piezoelectric metamaterials

    Data-driven Identification of Parametric Governing Equations of Dynamical Systems Using the Signed Cumulative Distribution Transform

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    This paper presents a novel data-driven approach to identify partial differential equation (PDE) parameters of a dynamical system. Specifically, we adopt a mathematical "transport" model for the solution of the dynamical system at specific spatial locations that allows us to accurately estimate the model parameters, including those associated with structural damage. This is accomplished by means of a newly-developed mathematical transform, the signed cumulative distribution transform (SCDT), which is shown to convert the general nonlinear parameter estimation problem into a simple linear regression. This approach has the additional practical advantage of requiring no a priori knowledge of the source of the excitation (or, alternatively, the initial conditions). By using training data, we devise a coarse regression procedure to recover different PDE parameters from the PDE solution measured at a single location. Numerical experiments show that the proposed regression procedure is capable of detecting and estimating PDE parameters with superior accuracy compared to a number of recently developed machine learning methods. Furthermore, a damage identification experiment conducted on a publicly available dataset provides strong evidence of the proposed method's effectiveness in structural health monitoring (SHM) applications. The Python implementation of the proposed system identification technique is integrated as a part of the software package PyTransKit (https://github.com/rohdelab/PyTransKit)

    A systems view of spliceosomal assembly and branchpoints with iCLIP.

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    Studies of spliceosomal interactions are challenging due to their dynamic nature. Here we used spliceosome iCLIP, which immunoprecipitates SmB along with small nuclear ribonucleoprotein particles and auxiliary RNA binding proteins, to map spliceosome engagement with pre-messenger RNAs in human cell lines. This revealed seven peaks of spliceosomal crosslinking around branchpoints (BPs) and splice sites. We identified RNA binding proteins that crosslink to each peak, including known and candidate splicing factors. Moreover, we detected the use of over 40,000 BPs with strong sequence consensus and structural accessibility, which align well to nearby crosslinking peaks. We show how the position and strength of BPs affect the crosslinking patterns of spliceosomal factors, which bind more efficiently upstream of strong or proximally located BPs and downstream of weak or distally located BPs. These insights exemplify spliceosome iCLIP as a broadly applicable method for transcriptomic studies of splicing mechanisms

    Emerging topics in nanophononics and elastic, acoustic, and mechanical metamaterials: an overview

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    This broad review summarizes recent advances and “hot” research topics in nanophononics and elastic, acoustic, and mechanical metamaterials based on results presented by the authors at the EUROMECH 610 Colloquium held on April 25–27, 2022 in Benicássim, Spain. The key goal of the colloquium was to highlight important developments in these areas, particularly new results that emerged during the last two years. This work thus presents a “snapshot” of the state-of-the-art of different nanophononics- and metamaterial-related topics rather than a historical view on these subjects, in contrast to a conventional review article. The introduction of basic definitions for each topic is followed by an outline of design strategies for the media under consideration, recently developed analysis and implementation techniques, and discussions of current challenges and promising applications. This review, while not comprehensive, will be helpful especially for early-career researchers, among others, as it offers a broad view of the current state-of-the-art and highlights some unique and flourishing research in the mentioned fields, providing insight into multiple exciting research directions
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