9 research outputs found

    Additional file 3: Figure S3. of Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

    Get PDF
    Spectrum of free fatty acids of DU145 cells after SCD inhibition. DU145 cells were treated with SCD inhibitors (100nM) or solvent (DMSO) for 48hrs in medium with low serum or supplemented with BSA or BSA-coupled oleic acid (BSA-oleate). (a) Amounts of different FFA species. (b) Amounts of selected saturated and mono-unsaturated FFAs. (c) Relative contribution of FFA species to total FFA pool. (d) Relative contribution of selected saturated and mono-unsaturated FFA species to total FFA pool. Data represent mean ±SEM of three independent biological replicates. Statistical comparisons were performed using Student t-test (*p≤0.05). (PDF 648 kb

    Project of Politeia as a base for impletion cross theme on education of a democracy citizen at the base level of primary school

    No full text
    I'm focused on the education of democratic citizen in the base level of Primary School in my diploma work "The project of Politeia as a base for impletion cross theme on education of a democracy citizen at the base level of primary school". I'm giving an information connected with education of citizen culture with general educational programme at primary schools and finally with the project Politeia which was the fundamental idea and impulse for this work. One part of this work is the analysis of the reform in the sphere of citizen culture education, aims and methods. The empirical part in focused on a creation of materials to be used for the realisation of the Cross Theme Education of a Democratic Citizen that gives full use at the base level of a primary school. The mentioned project brings working sheets above all that are accompanied by additional possible activities - for example malingering game. The empirical part was verified in practice at the second and third stage of the Primary School in Prague and it was appraised by teachers with different duration of their teaching career

    Additional file 5: Figure S5. of Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

    No full text
    Analysis of phosphatidylethanolamine species in DU145 cells following SCD inhibition. DU145 cells were treated with SCD inhibitors (100nM) or solvent (DMSO) for 48hrs in medium containing low serum. (a) Amounts of different PE species detected by LC-MS/MS. (b) Amounts of selected PE species. (c) Relative contribution of selected PE species to total PE pool. Data represent the mean ±SEM of three biologically independent replicates. Statistical comparisons were performed using Student t-test (*p≤0.05). (PDF 556 kb
    corecore