Population Geography Perspectives on the Central Asian Republics

Since the fall of the iron curtain, research on population issues in Central Asia, with the exception of migration, has lost ground in the academia, and little is known about the geographical dimensions of population issues in this region beyond the findings of the handful of studies carried out under the auspices of international organisations. Therefore, the purpose of this paper is to outline the main traits of the population geography of the Central Asian Republics of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan and Uzbekistan. The report investigates the geographical characteristics of the countries’ vital statistics, as well as of other significant demographic indicators, such as the age structure, dependency ratio and infant mortality. Additionally, the report attempts to establish whether particular regional and local demographies show inter-linkages with the specific socio-economic and/or cultural settings that they are embedded in. The report uses the systematic collection and analysis of data from statistical sources as its main method. Most of the statistical materials derive from the national statistical authorities of the USSR and its successor states, although additional and complementary data was collected from the US Bureau of Census’ international database web resource. The use of such data involves substantial methodological and interpretative difficulties, which this report discusses in detail. Applying a three-scale geographical approach on the study of the Central Asian Republics’ population development, this report demonstrates that there are significant variations in the territoriality of these countries’ demographies. The variations are indeed striking, and suggest that the five states will face distinctly spatially differentiated challenges with regard to the volume and type of healthcare that will be required, the nature of the demand for housing, social and cultural services, and the structure of the labour market, just to name a few examples. These challenges should be taken into greater consideration by policy-makers and other stakeholders, along with matters of more immediate concern, such as the poor health infrastructure and sanitary situation, the high rate of poverty, environmental degradation, and the economic and political instability in the southern regions, most recently epitomized by the Ferghana valley-based “tulip” revolution in Kyrgyzstan and the violent riots in the Uzbek city of Andijan.Population Geography Perspectives; Central Asian Republics

Reduced gradient algorithm for user equilibrium traffic assignment problem

A path-based algorithm is developed for the static traffic assignment problem (TAP). In each iteration, it decomposes the problem into origin-destination (OD) pairs and solves each subproblem separately using the Wolfe reduced gradient (RG) method. This method reduces the dimensions of each single-OD subproblem by selecting a basic path between the OD pair and reformulating the subproblem in terms of the nonbasic paths. A column generation technique is included to avoid path enumeration in large scale networks. Also, some speed-up techniques are designed to improve the computational efficiency. The algorithm shifts flows from costlier paths to cheaper paths; however, the amount of flow shifted from a costlier path is proportional to not only the travel time but also the flow on the path. It is applied to the Philadelphia and Chicago test problems, while different strategies for choosing the basic paths are examined. The RG algorithm shows an excellent convergence to relative gaps of the order of 1.0E-14 when compared against several reference TAP algorithms

Toward a comprehensive natural hazard mitigation framework : the consideration of land use planning in coastal communities

Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 1997.Includes bibliographical references.by Matthew M. Gentile.M.C.P

A Framework for Developing and Evaluating Algorithms for Estimating Multipath Propagation Parameters from Channel Sounder Measurements

A framework is proposed for developing and evaluating algorithms for extracting multipath propagation components (MPCs) from measurements collected by channel sounders at millimeter-wave frequencies. Sounders equipped with an omnidirectional transmitter and a receiver with a uniform planar array (UPA) are considered. An accurate mathematical model is developed for the spatial frequency response of the sounder that incorporates the non-ideal cross-polar beampatterns for the UPA elements. Due to the limited Field-of-View (FoV) of each element, the model is extended to accommodate multi-FoV measurements in distinct azimuth directions. A beamspace representation of the spatial frequency response is leveraged to develop three progressively complex algorithms aimed at solving the singlesnapshot maximum likelihood estimation problem: greedy matching pursuit (CLEAN), space-alternative generalized expectationmaximization (SAGE), and RiMAX. The first two are based on purely specular MPCs whereas RiMAX also accommodates diffuse MPCs. Two approaches for performance evaluation are proposed, one with knowledge of ground truth parameters, and one based on reconstruction mean-squared error. The three algorithms are compared through a demanding channel model with hundreds of MPCs and through real measurements. The results demonstrate that CLEAN gives quite reasonable estimates which are improved by SAGE and RiMAX. Lessons learned and directions for future research are discussed.Comment: 17 page

Classification of Human Retinal Microaneurysms Using Adaptive Optics Scanning Light Ophthalmoscope Fluorescein Angiography

Purpose. Microaneurysms (MAs) are considered a hallmark of retinal vascular disease, yet what little is known about them is mostly based upon histology, not clinical observation. Here, we use the recently developed adaptive optics scanning light ophthalmoscope (AOSLO) fluorescein angiography (FA) to image human MAs in vivo and to expand on previously described MA morphologic classification schemes. Methods. Patients with vascular retinopathies (diabetic, hypertensive, and branch and central retinal vein occlusion) were imaged with reflectance AOSLO and AOSLO FA. Ninety-three MAs, from 14 eyes, were imaged and classified according to appearance into six morphologic groups: focal bulge, saccular, fusiform, mixed, pedunculated, and irregular. The MA perimeter, area, and feret maximum and minimum were correlated to morphology and retinal pathology. Select MAs were imaged longitudinally in two eyes. Results. Adaptive optics scanning light ophthalmoscope fluorescein angiography imaging revealed microscopic features of MAs not appreciated on conventional images. Saccular MAs were most prevalent (47%). No association was found between the type of retinal pathology and MA morphology (P = 0.44). Pedunculated and irregular MAs were among the largest MAs with average areas of 4188 and 4116 μm2, respectively. Focal hypofluorescent regions were noted in 30% of MAs and were more likely to be associated with larger MAs (3086 vs. 1448 μm2, P = 0.0001). Conclusions. Retinal MAs can be classified in vivo into six different morphologic types, according to the geometry of their two-dimensional (2D) en face view. Adaptive optics scanning light ophthalmoscope fluorescein angiography imaging of MAs offers the possibility of studying microvascular change on a histologic scale, which may help our understanding of disease progression and treatment response

Modulation of Motor Vigor by Expectation of Reward Probability Trial-by-Trial Is Preserved in Healthy Ageing and Parkinson's Disease Patients

Motor improvements, such as faster movement times or increased velocity, have been associated with reward magnitude in determin-istic contexts. Yet whether individual inferences on reward probability influence motor vigor dynamically remains undetermined. We investigated how dynamically inferring volatile action-reward contingencies modulated motor performance trial-by-trial. We conducted three studies that coupled a reversal learning paradigm with a motor sequence task and used a validated hierarchical Bayesian model to fit trial-by-trial data. In Study 1, we tested healthy younger [HYA; 37 (24 females)] and older adults [HOA; 37 (17 females)], and medicated Parkinson's disease (PD) patients [20 (7 females)]. We showed that stronger predictions about the tendency of the action -reward contingency led to faster performance tempo, commensurate with movement time, on a trial-by-trial basis without robustly modulating reaction time (RT). Using Bayesian linear mixed models, we demonstrated a similar invigoration effect on performance tempo in HYA, HOA, and PD, despite HOA and PD being slower than HYA. In Study 2 [HYA, 39 (29 females)], we additionally showed that retrospective subjective inference about credit assignment did not contribute to differences in motor vigor effects. Last, Study 3 [HYA, 33 (27 females)] revealed that explicit beliefs about the reward tendency (confidence ratings) modulated performance tempo trial-by-trial. Our study is the first to reveal that the dynamic updating of beliefs about volatile action-reward contingencies positively biases motor performance through faster tempo. We also provide robust evidence for a preserved sensitivity of motor vigor to inferences about the action-reward mapping in aging and medicated PD

Modulation of motor vigour by expectation of reward probability trial-by-trial is preserved in healthy ageing and Parkinson's disease patients

Motor improvements, such as faster movement times or increased velocity, have been associated with reward magnitude in deterministic contexts. Yet whether individual inferences on reward probability influence motor vigour dynamically remains undetermined. We investigated how dynamically inferring volatile action-reward contingencies modulated motor performance trial-by-trial. We conducted three studies that coupled a one-armed bandit decision-making paradigm with a motor sequence task and used a validated hierarchical Bayesian model to fit trial-by-trial data. In Study 1, we tested healthy younger (HYA, 37 [13 males]) and older adults (HOA, 37 [20 males]), and medicated Parkinson's Disease patients (PD, 20 [13 males]). We showed that stronger predictions about the tendency of the action-reward contingency led to faster performance tempo-commensurate with movement time-on a trial-by-trial basis without robustly modulating reaction time (RT). Using Bayesian linear mixed models, we demonstrated a similar invigoration effect on performance tempo in HYA, HOA and PD, despite HOA and PD being slower than HYA. In Study 2 (HYA, 39 [10 males]), we additionally showed that retrospective subjective inference about credit assignment did not contribute to differences in motor vigour effects. Last, Study 3 (HYA, 33 [6 males]) revealed that explicit beliefs about the reward tendency (confidence ratings) modulated performance tempo trial-by-trial.Our study is the first to reveal that the dynamic updating of beliefs about volatile action-reward contingencies positively biases motor performance through faster tempo. We also provide robust evidence for a preserved sensitivity of motor vigour to inferences about the action-reward mapping in ageing and medicated PD.SIGNIFICANCE STATEMENT:Navigating a world rich in uncertainty relies on updating beliefs about the probability that our actions lead to reward. Here we investigated how inferring the action-reward contingencies in a volatile environment modulated motor vigour trial-by-trial in healthy younger and older adults, and in Parkinson's Disease patients on medication. We found an association between trial-by-trial predictions about the tendency of the action-reward contingency and performance tempo, with stronger expectations speeding the movement. We additionally provided evidence for a similar sensitivity of performance tempo to the strength of these predictions in all groups. Thus, dynamic beliefs about the changing relationship between actions and their outcome enhanced motor vigour. This positive bias was not compromised by age or Parkinson's disease