3,332 research outputs found

    Fighting the last war : preparations for the next oil crisis

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    This is a revised version of a paper presented to the 1986 Midwest Political Science Association Meeting, April 10, 198

    Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome

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    Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS). We report a 56-year-old man with a diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC) and ureteral transitional cell carcinoma who subsequently developed two sebaceous gland neoplasms and several keratoacanthomas, leading to the diagnosis of MTS. Our case highlights the clinical advantages of immunohistochemistry (IHC) in identifying mutations in the mismatch repair (MMR) genes responsible for both HNPCC and MTS. The importance of continued clinical suspicion in the dermatological assessment of patients with sebaceous neoplasms is emphasized

    Does a Carbonatite Deposit Influence Its Surrounding Ecosystem?

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    Carbonatites are unusual alkaline rocks with diverse compositions. Although previous work has characterized the effects these rocks have on soils and plants, little is known about their impacts on local ecosystems. Using a deposit within the Great Lakes–St. Lawrence forest in northern Ontario, Canada, we investigated the effect of a carbonatite on soil chemistry and on the structure of plant and soil microbial communities. This was done using a vegetation survey conducted above and around the deposit, with corresponding soil samples collected for determining soil nutrient composition and for assessing microbial community structure using 16S/ITS Illumina Mi-Seq sequencing. In some soils above the deposit a soil chemical signature of the carbonatite was found, with the most important effect being an increase in soil pH compared with the non-deposit soils. Both plants and microorganisms responded to the altered soil chemistry: the plant communities present in carbonatite-impacted soils were dominated by ruderal species, and although differences in microbial communities across the surveyed areas were not obvious, the abundances of specific bacteria and fungi were reduced in response to the carbonatite. Overall, the deposit seems to have created microenvironments of relatively basic soil in an otherwise acidic forest soil. This study demonstrates for the first time how carbonatites can alter ecosystems in situ

    Mucinous Adenocarcinoma of the Scalp: Primary Cutaneous Neoplasm Versus Underlying Metastatic Disease

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    Primary cutaneous mucinous carcinoma (PCMC) is a rare mucin-pro- ducing malignancy derived from epithelial glandular structures. The literature re- garding this topic is mostly in the form of case reports and case series. PCMC tends to present in the elderly with predilection for the head and neck and on initial assessment it can be easily mistaken for a simple inclusion cyst. Although PCMC is often indolent in nature, in rare instances it can metastasize and should remain a differential diagnosis in a selected population. The significance in identifying PCMC is reliably differentiating it from metastatic mucinous adenocarcinoma. We present a review of literature and case of PCMC on the scalp of a 67-year-old female. (Plast Reconstr Surg Glob Open 2018;6:e1761; doi: 10.1097/GOX.0000000000001761; Published online 16 April 2018.

    Managing the Going Concern Risk in an Uncertain Environment An Analysis of Regulatory Guidance and Financial Relief for the COVID-19 Pandemic

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    manufacturing company Regal Beloit reports that it has drawn $255 million on its line of credit, even though it has a strong balance sheet and does not currently intend to use the borrowed proceeds, but believes an abundance of caution regarding its cash position is prudent at this time. Management\u27s Responsibility The responsibility to prepare financial statements on a going concern basis under U.S. GAAP and the International Financial Reporting Standards (IFRS) falls on management. Managers must look forward for a reasonable period of time, defined as 12 months from the financial statement issue date or 12 months from the date financials would have been issued for entities that are neither SEC filers nor conduit bond obligors for debt securities that are traded in a public market. Under ASC 205-40, managers must disclose an uncertainty regarding the ability of the business to continue as a going concern if substantial doubt exists when the conditions and events described above, considered in aggregate, indicate that it is probable that the entity will be unable to meet obligations as they become due

    Silicate Emission in the TW Hydrae Association

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    The TW Hydrae Association is the nearest young stellar association. Among its members are HD 98800, HR 4796A, and TW Hydrae itself, the nearest known classical T Tauri star. We have observed these three stars spectroscopically between 3 and 13 microns. In TW Hya the spectrum shows a silicate emission feature that is similar to many other young stars with protostellar disks. The 11.2 micron feature indicative of significant amounts of crystalline olivine is not as strong as in some young stars and solar system comets. In HR 4796A, the thermal emission in the silicate feature is very weak, suggesting little in the way of (small silicate) grains near the star. The silicate band of HD 98800 (observed by us but also reported by Sylvester and Skinner (1996)) is intermediate in strength between TW Hya and HR 4796.Comment: 22 pages, 11 figures, LaTeX2e and AAS LaTeX macros v5.0. Accepted for publication in A

    Variation in Grazing Sward Chicory Content After Periods of Low Rainfall

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    Multispecies (MS) swards can reduce chemical nitrogen (N) fertiliser requirement due to the legume components of the sward mixtures, and have the potential to increase drought tolerance, particularly where chicory (CH, Chicorium intybus L.) is included in the sward mixture. A grazed plot experiment was established to investigate the persistency of forage herb species in MS swards under typical Irish grazing conditions. The swards contained three plant functional groups: grass, legume and herb; four sward types were established which included sward mixtures of the following species: perennial ryegrass (PRG, Lolium perenne L.) white clover (WC, Trifolium repens L.), red clover (RC, Trifolium pratense L.), CH and ribwort plantain (PL, Plantago lanceolata L.). The sward content of the various species in the sown mixtures was evaluated over three years (2020, 2021 and 2022). The summer of 2022 experienced dry weather conditions in which rainfall was well below average thus providing an opportunity to assess the drought tolerance of CH in grazed swards. The proportion of sward CH content from two late season cuts was assessed over the three years and this study reports the changes in sward CH content between years and grazing rotations. Average sward CH content was 14.7, 6.1, and 1.5% across all sward types in late summer of 2020, 2021 and 2022, respectively; average sward CH content was 13.7, 9.4 and 24.6 across all sward types in autumn of 2020, 2021 and 2022, respectively
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