582 research outputs found
Using voice to tag digital photographs on the spot
Tagging of media, particularly digital photographs, has become a very popular and efficient means of organizing material on the internet and on personal computers. Tagging, though, is normally accomplished long after the images have been captured, possibly at the expense of in-the-moment information. Although some digital cameras have begun to automatically populate the various fields of a photograph\u27s metadata, these generic labels often lack in the descriptiveness presented through user-observed annotations and therefore stress the necessity of a user-driven input method. However, most mobile annotation applications demand a great number of keystrokes in order for users to tag photographs and thereby focus the user\u27s attention inward. Specifically, the problem is that these applications require users to take their eyes off the environment while typing in tags. We hypothesize that we can shift the user\u27s focus away from the mobile device and back to their environment by creating a mobile annotation application which accepts voice commands. In other words, our major hypothesis is that a convenient way of tagging digital photographs is by using voice commands
In Vivo Survival and Homeostatic Proliferation of Natural Killer Cells
While the specificity and development of natural killer (NK) cells have been intensely studied, little is known about homeostasis of the mature NK population. Here we show that mouse NK cells undergo homeostatic proliferation when transferred into NK-deficient Rag−/− γC−/− hosts. Normal NK functional activity is maintained during this process, although there are some changes in NK phenotype. Using cell sorting, we demonstrate that mature (Mac-1hi) NK cells undergo homeostatic proliferation in an NK-deficient environment, yet immature (Mac-1lo) NK cells also proliferate in such hosts. We find that mature NK cells survive but do not proliferate in hosts which possess an endogenous NK pool. However, we go on to show that mature NK survival is critically dependent on interleukin (IL)-15. Surprisingly, NK survival is also compromised after transfer of cells into IL-15Rα−/− mice, implying that IL-15 responsiveness by bystander cells is critical for NK maintenance. These data imply that, similar to T cells, homeostasis of the NK pool is much more dynamic than previously appreciated and this may be relevant to manipulation of NK cells for therapeutic purposes
Accuracy of wind observations from open-ocean buoys: Correction for flow distortion
The comparison of equivalent neutral winds obtained from (a) four WHOI buoys in the subtropics and (b) scatterometer estimates at those locations reveals a root-mean-square (RMS) difference of 0.56-0.76 m/s. To investigate this RMS difference, different buoy wind error sources were examined. These buoys are particularly well suited to examine two important sources of buoy wind errors because: (1) redundant anemometers and a comparison with numerical flow simulations allow us to quantitatively assess flow distortion errors, and (2) one-minute sampling at the buoys allows us to examine the sensitivity of buoy temporal sampling/averaging in the buoy-scatterometer comparisons. The inter-anemometer difference varies as a function of wind direction relative to the buoy wind vane and is consistent with the effects of flow distortion expected based on numerical flow simulations. Comparison between the anemometers and scatterometer winds supports the interpretation that the inter-anemometer disagreement, which can be up to 5% of the wind speed, is due to flow distortion. These insights motivate an empirical correction to the individual anemometer records and subsequent comparison with scatterometer estimates show good agreement
Regulation of L-Selectin–mediated Rolling through Receptor Dimerization
L-selectin binding activity for its ligand expressed by vascular endothelium is rapidly and transiently increased after leukocyte activation. To identify mechanisms for upregulation and assess how this influences leukocyte/endothelial cell interactions, cell-surface dimers of L-selectin were induced using the coumermycin–GyrB dimerization strategy for cross-linking L-selectin cytoplasmic domains in L-selectin cDNA-transfected lymphoblastoid cells. Coumermycin- induced L-selectin dimerization resulted in an approximately fourfold increase in binding of phosphomanan monoester core complex (PPME), a natural mimic of an L-selectin ligand, comparable to that observed after leukocyte activation. Moreover, L-selectin dimerization significantly increased (by ∼700%) the number of lymphocytes rolling on vascular endothelium under a broad range of physiological shear stresses, and significantly slowed their rolling velocities. Therefore, L-selectin dimerization may explain the rapid increase in ligand binding activity that occurs after leukocyte activation and may directly influence leukocyte migration to peripheral lymphoid tissues or to sites of inflammation. Inducible oligomerization may also be a common mechanism for rapidly upregulating the adhesive or ligand-binding function of other cell-surface receptors
Wide-angle elastic scattering and color randomization
Baryon-baryon elastic scattering is considered in the independent scattering
(Landshoff) mechanism. It is suggested that for scattering at moderate
energies, direct and interchange quark channels contribute with equal color
coefficients because the quark color is randomized by soft gluon exchange
during the hadronization stage. With this assumption, it is shown that the
ratio of cross sections at CM angle
decreases from a high energy value of R_{\pbar p / pp} \approx 1/2.7, down to
R_{\pbar p / pp} \approx 1/28, compatible with experimental data at moderate
energies. This sizable fall in the ratio seems to be characteristic of the
Landshoff mechanism, in which changes at the quark level have a strong effect
precisely because the hadronic process occurs via multiple quark scatterings.
The effect of color randomization on the angular distribution of proton-proton
elastic scattering and the cross section ratio is also discussed.Comment: 18 pages, latex2e, 4 uuencoded figures, include
Restorative Youth Sports: An Applied Model for Resolving Conflicts and Building Positive Relationships
When handled effectively, conflict provides opportunities to strengthen relationships and assist youth in developing peaceful conflict resolution skills. Sport participation is one context in which youth develop skills and encounter conflict. The purpose of this study was to develop an applied model that addresses conflict resolution in sport-based youth development programs. Using qualitative interviewing, a community-engaged approach guided the selection of participants and data analysis. We used the models of restorative practice and Teaching Personal and Social Responsibility (TPSR) through sports to guide our study. Following interviews with a variety of community partners, we found that the values of sport are often in conflict with restorative practices. However, a relational approach such as TPSR aligns well with the values of restorative practices. Based on our findings, an applied model was developed to illustrate how restorative practice can be utilized in a sport context. The Restorative Youth Sports (RYS) model recognizes that conflicts and tension are natural and inherent to all relationships. When handled appropriately, conflict provides opportunities to strengthen relationships. Youth sport provides a unique context where youth are presented with problems and conflicts to solve and promote healthy relationships among youth
Diagnosing Spin at the LHC via Vector Boson Fusion
We propose a new technique for determining the spin of new massive particles
that might be discovered at the Large Hadron Collider. The method relies on
pair-production of the new particles in a kinematic regime where the vector
boson fusion production mechanism is enhanced. For this regime, we show that
the distribution of the leading jets as a function of their relative azimuthal
angle can be used to distinguish spin-0 from spin-1/2 particles. We illustrate
this effect by considering the particular cases of (i) strongly-interacting,
stable particles and (ii) supersymmetric particles carrying color charge. We
argue that this method should be applicable in a wide range of new physics
scenarios.Comment: 5 pages, 4 figure
The B-L/Electroweak Hierarchy in Smooth Heterotic Compactifications
E8 X E8 heterotic string and M-theory, when appropriately compactified, can
give rise to realistic, N=1 supersymmetric particle physics. In particular, the
exact matter spectrum of the MSSM, including three right-handed neutrino
supermultiplets, one per family, and one pair of Higgs-Higgs conjugate
superfields is obtained by compactifying on Calabi-Yau manifolds admitting
specific SU(4) vector bundles. These "heterotic standard models" have the
SU(3)_{C} X SU(2)_{L} X U(1)_{Y} gauge group of the standard model augmented by
an additional gauged U(1)_{B-L}. Their minimal content requires that the B-L
gauge symmetry be spontaneously broken by a vacuum expectation value of at
least one right-handed sneutrino. In a previous paper, we presented the results
of a renormalization group analysis showing that B-L gauge symmetry is indeed
radiatively broken with a B-L/electroweak hierarchy of O(10) to O(10^{2}). In
this paper, we present the details of that analysis, extending the results to
include higher order terms in tan[beta]^{-1} and the explicit spectrum of all
squarks and sleptons.Comment: 60 pages, 6 figure
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