90 research outputs found
Residual Strength and Durability of Glass fiber FRCM and CRM Systems Aged in Alkaline Environments
Fabric Reinforced Cementitious Matrix (FRCM) and Composite Reinforced Mortar (CRM) systems are used as Externally Bonded Reinforcements (EBR) in civil and historical construction. These materials are made by fibrous reinforcement, in forms of dry (FRCM) or cured (CRM) meshes embedded in a cementitious/hydraulic lime matrix. At present, this technology is considered very promising in the field of structural strengthening, retrofitting and repair existing structures. This is true especially in those cases of masonry and historical buildings, due to the specific criteria of conservation and compatibility with the substrate that need to be fulfilled. These materials, in fact, results more compatible with masonry substrate because of the inorganic matrix, instead of polymeric resin used for the well-known FRP systems (Fiber Reinforced Polymers). The recent use of these new materials in civil engineering needs appropriate and complete guidelines, that regard not only the design aspects but also the durability features. This paper presents the results of a large experimental program focused on the durability of FRCM and CRM systems and their single components, in different alkaline environments. For the whole experimental campaign, the samples have been immersed into three different alkaline solutions, for four exposure times (500, 1000, 2000 and 3000 hrs). In addition, in order to study the different accelerating effects due to temperature, three different temperatures were maintained during the ageing periods: 23°C, 40°C and 70°C. The results about the mechanical characterization of residual properties are discussed in order to highlight the influence of alkaline environments on the mechanical properties of single elements and the whole strengthening systems that were tested herein
Respiratory chain complex I, a main regulatory target of the cAMP/PKA pathway is defective in different human diseases
In mammals, complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain has 31 supernumerary subunits in addition to the 14 conserved from prokaryotes to humans. Multiplicity of structural protein components, as well as of biogenesis factors, makes complex I a sensible pace-maker of mitochondrial respiration. The work reviewed here shows that the cAMP/PKA pathway regulates the biogenesis, assembly and catalytic activity of complex I and mitochondrial oxygen superoxide production. The structural, functional and regulatory complexity of complex I, renders it particularly vulnerable to genetic and sporadic pathological factors. Complex I dysfunction has, indeed, been found, to be associated with several human diseases. Knowledge of the pathogenetic mechanisms of these diseases can help to develop new therapeutic strategies. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved
Prototype ATLAS IBL Modules using the FE-I4A Front-End Readout Chip
The ATLAS Collaboration will upgrade its semiconductor pixel tracking
detector with a new Insertable B-layer (IBL) between the existing pixel
detector and the vacuum pipe of the Large Hadron Collider. The extreme
operating conditions at this location have necessitated the development of new
radiation hard pixel sensor technologies and a new front-end readout chip,
called the FE-I4. Planar pixel sensors and 3D pixel sensors have been
investigated to equip this new pixel layer, and prototype modules using the
FE-I4A have been fabricated and characterized using 120 GeV pions at the CERN
SPS and 4 GeV positrons at DESY, before and after module irradiation. Beam test
results are presented, including charge collection efficiency, tracking
efficiency and charge sharing.Comment: 45 pages, 30 figures, submitted to JINS
Repair of composite-to-masonry bond using flexible matrix
The paper presents an experimental investigation on an innovative repair method, in which composite
reinforcements, after debonding, are re-bonded to the substrate using a highly deformable polymer. In order
to assess the effectiveness of this solution, shear bond tests were carried out on brick and masonry substrates within two Round Robin Test series organized within the RILEM TC 250-CSM: Composites for Sustainable strengthening of Masonry. Five laboratories from Italy, Poland and Portugal were involved. The shear bond performance of the reinforcement systems before and after repair were compared in terms of ultimate loads, load-displacement curves and strain distributions. The results showed that the proposed repair method may provide higher strength and ductility than stiff epoxy resins, making it an effective and cost efficient technique for several perspective structural applications
Amyloid-ÎČ-Induced Ion Flux in Artificial Lipid Bilayers and Neuronal Cells: Resolving a Controversy
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