434 research outputs found
Bis[2-(2-pyridylmethyleneamino)benzenesulfonato-κ3 N,N′,O]cobalt(II) dihydrate
The title complex, [Co(C12H9N2O3S)2]·2H2O, has site symmetry 2 with the CoII cation located on a twofold rotation axis. Two tridentate 2-(2-pyridylmethyleneamino)benzenesulfonate (paba) ligands chelate to the CoII cation in a distorted octahedral geometry. The pyridine and benzene rings in the paba ligand are oriented at a dihedral angle of 42.86 (13)°. Intermolecular O—H⋯O and C—H⋯O hydrogen bonding is present in the crystal structure
Bis[2-(2-pyridylmethyleneamino)benzenesulfonato]-κ3 N,N′,O;κ2 N,N′-copper(II)
In the mononuclear title compound, [Cu(C12H9N2O3S)2], the copper(II) salt of 2-(2-pyridylmethyleneamino)benzenesulfonic acid, the CuII atom is coordinated by one O and two N atoms from a monoanion as well as by two N atoms from another monoanion in a distorted trigonal-bipyramidal environment
Bis[2-(2-pyridylmethyleneamino)benzenesulfonato-κ3 N,N′,O]cadmium(II) dihydrate
The title complex, [Cd(Paba)2]·2H2O or [Cd(C12H9N2O3S)2]·2H2O, was synthesized by the reaction of the potassium salt of 2-(2-pyridylmethyleneamino)benzenesulfonic acid (PabaK) with CdCl2·2.5H2O in methanol. The CdII atom lies on a crystallographic twofold axis and is coordinated by four N atoms and two O atoms from two deprotonated tridentate 2-(2-pyridylmethyleneamino)benzenesulfonate ligands in a slightly distorted octahedral environment. There are extensive hydrogen bonds of the type O—H⋯O between the uncoordinated water molecules and the sulfonate O atoms, through which the complex forms a layered structure parallel to (001)
Poly[tris(μ3-2-aminoethanesulfonato)cobalt(II)potassium]
The title compound, [CoK(C2H6NO3S)3]n, is isotypic with its NiII analogue. The CoII atom is chelated by the three taurinate ligands in a distorted octahedral geometry and in a facial manner. Each taurinate ligand bridges two K+ ions via its sulfonate group, forming a three-dimensional framework. Weak N—H⋯O hydrogen bonding is observed in the crystal structure
GW25-e3168 Sodium tashinoneIIA sulfonate improves tachycardia-induced electrical remodeling of canine
Numerical observation of non-axisymmetric vesicles in fluid membranes
By means of Surface Evolver (Exp. Math,1,141 1992), a software package of
brute-force energy minimization over a triangulated surface developed by the
geometry center of University of Minnesota, we have numerically searched the
non-axisymmetric shapes under the Helfrich spontaneous curvature (SC) energy
model. We show for the first time there are abundant mechanically stable
non-axisymmetric vesicles in SC model, including regular ones with intrinsic
geometric symmetry and complex irregular ones. We report in this paper several
interesting shapes including a corniculate shape with six corns, a
quadri-concave shape, a shape resembling sickle cells, and a shape resembling
acanthocytes. As far as we know, these shapes have not been theoretically
obtained by any curvature model before. In addition, the role of the
spontaneous curvature in the formation of irregular crenated vesicles has been
studied. The results shows a positive spontaneous curvature may be a necessary
condition to keep an irregular crenated shape being mechanically stable.Comment: RevTex, 14 pages. A hard copy of 8 figures is available on reques
Meteorite classification for building the Chinese Antarctic Meteorite Depository—Introduction of the classification of 500 Grove Mountains meteorites
Meteorites provide an important window into the origins and evolution of the solar system. Since the first four meteorites were recovered in Grove Mountains, Antarctica, in 1998, a further total of 12665 meteorites have been collected over seven polar seasons in the Grove Mountains. All of these meteorites are owned and managed by the Chinese Antarctic Meteorite Depository (CAMD) at the Polar Research Institute of China (PRIC). In recent years, another 500 Antarctic meteorites have been classified and characterized based on mineralogy and petrology. In this work we examine four samples that have been identified as terrestrial, and a further 496 samples that have been confirmed as meteorites. These meteorites are further divided into different types:488 ordinary chondrites, one eucrite, one ureilite, one CM2 carbonaceous chondrite, one EH4 enstatite chondrite, one mesosiderite and three iron meteorites. The classification of meteorites not only provides an abundance of fundamental scientific data, but is also significant for introducing meteorites and related scientific knowledge to the public, particularly via the website of Chinese Resource-sharing Platform of Polar Samples for scientific research and education
Macrophage CGI-58 Deficiency Activates ROS-Inflammasome Pathway to Promote Insulin Resistance in Mice
SummaryOvernutrition activates a proinflammatory program in macrophages to induce insulin resistance (IR), but its molecular mechanisms remain incompletely understood. Here, we show that saturated fatty acid and lipopolysaccharide, two factors implicated in high-fat diet (HFD)-induced IR, suppress macrophage CGI-58 expression. Macrophage-specific CGI-58 knockout (MaKO) in mice aggravates HFD-induced glucose intolerance and IR, which is associated with augmented systemic/tissue inflammation and proinflammatory activation of adipose tissue macrophages. CGI-58-deficient macrophages exhibit mitochondrial dysfunction due to defective peroxisome proliferator-activated receptor (PPAR)γ signaling. Consequently, they overproduce reactive oxygen species (ROS) to potentiate secretion of proinflammatory cytokines by activating NLRP3 inflammasome. Anti-ROS treatment or NLRP3 silencing prevents CGI-58-deficient macrophages from oversecreting proinflammatory cytokines and from inducing proinflammatory signaling and IR in the cocultured fat slices. Anti-ROS treatment also prevents exacerbation of inflammation and IR in HFD-fed MaKO mice. Our data thus establish CGI-58 as a suppressor of overnutrition-induced NLRP3 inflammasome activation in macrophages
Almost sure consensus for multi-agent systems with two level switching
In most literatures on the consensus of multi-agent systems (MASs), the agents considered are time-invariant. However in many cases, for example in airplane formation, the agents have switching dynamics and the connections between them are also changing. This is called two-level switching in this paper. We study almost sure (AS) consensus for a class of two-level switching systems. At the low level of agent dynamics, switching is determin- istic and controllable. The upper level topology switching is random and follows a Markov chain. The transition probability of the Markov chain is not fixed, but varies when low level dynamics changes. For this class of MASs, a sufficient condition for AS consensus is developed in this paper
Second variation of the Helfrich-Canham Hamiltonian and reparametrization invariance
A covariant approach towards a theory of deformations is developed to examine
both the first and second variation of the Helfrich-Canham Hamiltonian --
quadratic in the extrinsic curvature -- which describes fluid vesicles at
mesoscopic scales. Deformations are decomposed into tangential and normal
components; At first order, tangential deformations may always be identified
with a reparametrization; at second order, they differ. The relationship
between tangential deformations and reparametrizations, as well as the coupling
between tangential and normal deformations, is examined at this order for both
the metric and the extrinsic curvature tensors. Expressions for the expansion
to second order in deformations of geometrical invariants constructed with
these tensors are obtained; in particular, the expansion of the Hamiltonian to
this order about an equilibrium is considered. Our approach applies as well to
any geometrical model for membranes.Comment: 20 page
- …