555 research outputs found

    A COMPARATIVE STUDY ON THE EFFECT OF LIQUOR RATIO OF ACID AND NEUTRAL(POWDER) ENZYME ON DENIM GARMENTS

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    Young people as well as older people have now great passion for the denim cloth. Today jeans are available in many colors and designs. In this study we tried to reveal the difference in between two types of cellulase enzymes acid and neutral (powder) enzyme. To do this, denim samples were collected and prepared according to the recipe of equal amount of enzyme by varying the liquor ratio. Basically there were no differences found in between acid and powder enzyme on different fastness properties like rubbing, washing, perspiration, light fastness test. But there was a significant difference in weight loss%. Acid enzyme exhibited little bit more enzymatic effect than powder enzyme and it also showed more weight loss % . But the neutral enzyme required less money rather than acid enzyme and no need to control pH, easy to use. Moreover, lower liquor ratio gave higher abrasion. Acid enzyme gave more back staining than neutral enzyme

    Investigating Structural Relationship among Service Quality Dimensions, Customer Satisfaction, and Customer Loyalty for Conventional Bank Customers: Evidence from Bangladesh

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    Customers of the banks are highly servicing sensitive in Bangladesh. The quality of service has become an integral part of customer satisfaction. Day by day, It has been demonstrated that customer satisfaction and loyalty are linked to service quality. There is also a link between service quality and customer satisfaction, and customer loyalty in banks. Therefore, this paper investigated the effect of service quality factors on customer satisfaction and the relationship between customer satisfaction and customer loyalty in conventional banks in Bangladesh. A survey was conducted on 13 different conventional banks in Bangladesh. Using simple random sampling, 220 customers were selected as a sample from selected conventional banks for this study. The research was carried out using a structured questionnaire. The SPSS software was used to analyze the demographic data. Multivariate analysis technique like Factor Analysis and Structural Equation Modeling (SEM) was used to identify the influential factors for the bank's customer loyalty by using SmartPLS3 software. The study found that all service quality factors such as assurance, reliability, responsiveness, and tangibility are the influential factors except empathy

    植物研究のためのディスポーザブルマイクロセンサの開発

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    筑波大学 (University of Tsukuba)201

    EFFECTS OF READING TEXT WHILE DRIVING ANALYSIS OF 200 HONOLULU TAXI DRIVERS ON A VS500M SIMULATOR

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    M.S. Thesis. University of Hawaiʻi at Mānoa 2018

    Improvement of Deep Tubewell Irrigation Project Performance in Bangladesh

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    A computer model for use in predicting the impact of various improvement options on command area expansion of a deep tubewell irrigation system has been developed. A field study was conducted on 11 selected deep tubewells located at two sites, namely Dhamrai and Thakurgaon, in Bangladesh to collect necessary physical data to provide irrigation engineering insight and a basis for testing and application of the model. The results of the investigation revealed that the actual discharge of most of the deep tubewells was lower than the design or rated capacity. The duration of pump operation in the majority of the study deep tubewell areas was extremely low. The conveyance losses in all of the study systems were very high. Even though a portion of those losses was reused in the system, particularly in rice growing areas, they caused serious difficulty in delivering water to remote fields, thus, restricting the command area. The overall irrigation efficiencies in all of the wheat growing areas of Thakurgaon were low. Considerable losses and waste of water after it was diverted from the field channels due to lack of leveling and poor water control were mostly responsible for the low efficiencies . Excessive percolation losses due to inadequate puddling of the soils during land preparation and frequent drought conditions resulted from poor distribution of water in some of the rice growing areas of Dhamrai caused relatively low overall irrigation efficiencies. The overall efficiencies of the pumps both driven by diesel engine and electric motor were found to be much lower than the recommended values. The developed model was applied to predict the expected command area under both existing and modified physical conditions. The model predicted command areas were compared with the actual field observed values and necessary adjustments were discussed. The impact of each of the improvement alternatives considered in the study was determined by comparing the predicted command area under the modified conditions with that under the existing physical settings. An economic analysis was performed to determine the cost effectiveness of most of the alternatives. Application of the model in evaluating the farmers\u27 pump operation practices was demonstrated. Use of the model to assist the farmers in planning the command area and delivery schedule was also indicated. Although the model was developed to use in a deep tubewell irrigation system, it can also be used in the system served by a low-lift pump or by a turnout in a large irrigation project

    Impact of Sectoral Growth on the Economic Development of Bangladesh: An Experimental Study

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    The study investigates the impact of sectoral growth on the economic development of Bangladesh. It has been accomplished from the viewpoint of financial intermediaries as well as real estate, renting and business activities sectors. The secondary data, for the period fiscal year (FY) 1995-1996 to the fiscal year (FY) 2018-2019, has been used to perform the analysis. The dependent variable in this study is the gross domestic product (GDP) representing the development status of the economy of Bangladesh. The independent variables- monetary intermediation (banks) sector (MIS), insurance sector (IS), other financial auxiliaries sector (FAS), real estate, renting and business activity sector (RBS) - have been used to show the relationship with GDP. A Multiple regression analysis has been used to develop the relationship. Besides, the coefficient of determination shows 70.2 % of the variance in GDP can be predicted from the independent variables. If other independent variables are incorporated in the model, 63.6% of the variation in the dependent variable (GDP) can be explained by the independent variables, which is observed by adjusted R-square value. In the analysis, it has been found a considerable effect of monetary intermediation (banks) sector (MIS), insurance sector (IS), other financial auxiliaries sector (FAS), real estate renting and business activity sector (RBS) on GDP of Bangladesh. Finally, application of the outcome of this study will be effective only to the economy of Bangladesh. Keywords: GDP, Monetary Intermediation, Correlation, Regression, Financial Auxiliaries sector (FAS), Analysis of Variance (ANOVA). DOI: 10.7176/RJFA/11-14-09 Publication date:July 31st 202

    The role and mechanism of action of BRK in breast cancer progression

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    Breast cancer is unanimously considered a highly heterogeneous disease due to its diverse molecular features. Breast tumor kinase (BRK), also known as protein tyrosine kinase 6 (PTK6), is a non-receptor tyrosine kinase that is highly expressed in over 80% of breast carcinomas. The role and mechanism of action of enzymatically activated BRK in breast pathology are unclear. The objectives of this project were to reveal the effect of BRK activation on cell migration, proliferation and tumorigenesis. We also aimed to determine the mechanism of action of BRK in the promotion of cell proliferation. We used BRK-negative cells (MCF10A, MDA-MB-231 and HEK293) to generate three sets of stable cell lines that stably expressed GFP alone, GFP-BRK-WT or GFP-BRK-Y447F (constitutively active) by retroviral infections. We also stably knocked down BRK from BRK-positive cells BT20 and SKBR3 by RNA interference using shRNAs against BRK. Western blotting, immunoprecipitation and qPCR studies were conducted to evaluate protein expression, protein-protein interaction and mRNA expression, respectively. Both sets of cell lines were used to determine the effect of BRK on cell proliferation (automated cell counter), cell migration (transwell and wound healing assay), transformation (colony formation assay) and tumor formation (mouse Xenograft assay). To investigate the mechanism of action of BRK, we validated downstream of tyrosine kinases 1 (Dok1), a tumor suppressor, as a BRK substrate. Deletion or site-directed mutagenesis was performed to map BRK-targeted tyrosines in Dok1 protein. Results obtained from this research project showed that stable expression of the constitutively active mutant of BRK (BRK-Y447F) in MDA-MB-231 cells led to a significant increase in the cell proliferation, migration rate and promoted colony formation and drastically enhanced tumor formation in athymic nude mice in comparison to control cells. Additionally, depletion of BRK abrogated the migration of BT20 and SKBR3 cells. Furthermore, we showed that BRK interacts with and phosphorylates Dok1, inducing Dok1 downregulation via a ubiquitin-proteasome-mediated mechanism. Together, our results show that the activation of BRK is essential for mammary gland tumorigenesis and suggest that targeting of Dok1 for degradation is a novel mechanism of action of BRK in the promotion of cell proliferation, migration and tumor formation
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