58 research outputs found

    A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency

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    Steroid 21-hydroxylase deficiency accounts for about 95% of cases of congenital adrenal hyperplasia (CAH). Newborns are currently being screened for the classical forms of this disease throughout the United States and in 12 other countries. As such, it seems important to develop the best practice guidelines for treating not only infants and children, but affected adults as well. This report gives a brief overview of the most recent expert opinion and clinical practice guidelines for CAH as formulated by The Endocrine Society Task Force

    Gender dysphoria and autism spectrum disorder: a systematic review of the literature

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    Introduction. There is a growing clinical recognition that a significant proportion of patients with Gender Dysphoria, have concurrent Autism Spectrum Disorder (ASD). Aim. The purpose of this review is to systematically appraise the current literature regarding the co-occurrence of Gender Dysphoria and ASD. Methods. A systematic literature search using Medline/Pubmed, PsycINFO and Embase were conducted from 1966 to July 2015. Main Outcome Measures. A total of 58 articles were generated from the search. Nineteen of these publications met the inclusion criteria. Results. The literature investigating ASD in children and adolescents with Gender Dysphoria have found a higher prevalence rate of ASD compared to the general population. There is a limited amount of research in adults. Only one study showed that adults attending services for Gender Dysphoria had increased ASD scores. Another study showed a higher proportion of atypical gender identity in adults with ASD. Conclusions. Although the research is limited, especially with adults, there is an increasing amount of evidence that suggests a co-occurrence between Gender Dysphoria and ASD. Further research is vital for educational and clinical purposes

    Human sex differences. A primatologist's perspective

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    52.1 INTRODUCTION: ASSESSMENT OF TRANSGENDER IDENTITY

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    Estrogens in human psychosexual differentiation

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