Interim report on the hydrologic features of the Green Swamp area in Central Florida

The Green Swamp area in central Florida is another area where man is developing agricultural land from marginal land. Though the area is by no means as extensive as that of the Everglades, the present efforts for its development are similar to the early efforts for developing the Everglades in that many miles of canals and ditches have been constructed to improve the drainage. Lest the early mistakes of the Everglades be repeated, the Florida Department of Water Resources considered that an appraisal of the physical and hydrologic features of the area was needed to determine the broad effects of draining and developing the swamp. This reconnaissance provides information required by the State of Florida for determining its responsibility and policy in regard to the Green Swamp area and for formulating future plans for water management of the area. Some of the features that have been determined are: the amount of rainfall on the area; the pattern of surfacewater drainage; the amount and direction of surface-water runoff; the direction of ground-water movement; the interrelationship of rainfall, surface water, and ground water; the effects of improved drainage facilities'; and the effects of the hydrologic environment on the chemical quality of water of the area.(PDF contains 106 pages.

Dietary elimination of children with food protein induced gastrointestinal allergy – micronutrient adequacy with and without a hypoallergenic formula?

Background: The cornerstone for management of Food protein-induced gastrointestinal allergy (FPGIA) is dietary exclusion; however the micronutrient intake of this population has been poorly studied. We set out to determine the dietary intake of children on an elimination diet for this food allergy and hypothesised that the type of elimination diet and the presence of a hypoallergenic formula (HF) significantly impacts on micronutrient intake. Method: A prospective observational study was conducted on children diagnosed with FPIGA on an exclusion diet who completed a 3 day semi-quantitative food diary 4 weeks after commencing the diet. Nutritional intake where HF was used was compared to those without HF, with or without a vitamin and mineral supplement (VMS). Results: One-hundred-and-five food diaries were included in the data analysis: 70 boys (66.7%) with median age of 21.8 months [IQR: 10 - 67.7]. Fifty-three children (50.5%) consumed a HF and the volume of consumption was correlated to micronutrient intake. Significantly (p <0.05) more children reached their micronutrient requirements if a HF was consumed. In those without a HF, some continued not to achieve requirements in particular for vitamin D and zinc, in spite of VMS. Conclusion: This study points towards the important micronutrient contribution of a HF in children with FPIGA. Children, who are not on a HF and without a VMS, are at increased risk of low intakes in particular vitamin D and zinc. Further studies need to be performed, to assess whether dietary intake translates into actual biological deficiencies

Quantum Chinos Game: winning strategies through quantum fluctuations

We apply several quantization schemes to simple versions of the Chinos game. Classically, for two players with one coin each, there is a symmetric stable strategy that allows each player to win half of the times on average. A partial quantization of the game (semiclassical) allows us to find a winning strategy for the second player, but it is unstable w.r.t. the classical strategy. However, in a fully quantum version of the game we find a winning strategy for the first player that is optimal: the symmetric classical situation is broken at the quantum level.Comment: REVTEX4.b4 file, 3 table

Quantum walks on two-dimensional grids with multiple marked locations

The running time of a quantum walk search algorithm depends on both the structure of the search space (graph) and the configuration of marked locations. While the first dependence have been studied in a number of papers, the second dependence remains mostly unstudied. We study search by quantum walks on two-dimensional grid using the algorithm of Ambainis, Kempe and Rivosh [AKR05]. The original paper analyses one and two marked location cases only. We move beyond two marked locations and study the behaviour of the algorithm for an arbitrary configuration of marked locations. In this paper we prove two results showing the importance of how the marked locations are arranged. First, we present two placements of $k$ marked locations for which the number of steps of the algorithm differs by $\Omega(\sqrt{k})$ factor. Second, we present two configurations of $k$ and $\sqrt{k}$ marked locations having the same number of steps and probability to find a marked location

Advection-dominated Inflow/Outflows from Evaporating Accretion Disks

In this Letter we investigate the properties of advection-dominated accretion flows (ADAFs) fed by the evaporation of a Shakura-Sunyaev accretion disk (SSD). In our picture the ADAF fills the central cavity evacuated by the SSD and extends beyond the transition radius into a coronal region. We find that, because of global angular momentum conservation, a significant fraction of the hot gas flows away from the black hole forming a transsonic wind, unless the injection rate depends only weakly on radius (if $r^2\dot\sigma\propto r^{-\xi}$, $\xi< 1/2$). The Bernoulli number of the inflowing gas is negative if the transition radius is $\lesssim 100$ Schwarzschild radii, so matter falling into the hole is gravitationally bound. The ratio of inflowing to outflowing mass is $\approx 1/2$, so in these solutions the accretion rate is of the same order as in standard ADAFs and much larger than in advection-dominated inflow/outflow models (ADIOS). The possible relevance of evaporation-fed solutions to accretion flows in black hole X-ray binaries is briefly discussed.Comment: 5 pages Latex with 2 ps figures. Accepted for publication in ApJ Letter

On the role of the UV and X-ray radiation in driving a disk wind in X-ray binaries

X-ray heating of the photosphere of an accretion disk is a possible mechanism to produce strong, broad UV emission lines in low mass X-ray binaries (LMXBs). However, detailed photoionization calculations show that this mechanism fails to produce sufficient emission measure. We present the results of hydrodynamical calculations of the disk photosphere irradiated by strong X-rays. We attempt to determine whether LMXBs can harbor significant UV-driven disk winds despite the effects of X-ray ionization. Such winds would be a likely candidate for the site of emission of UV lines and may better explain the observations than the X-ray heated disk photosphere. We find that the local disk radiation cannot launch a wind from the disk because of strong ionizing radiation from the central object. Unphysically high X-ray opacities would be required to shield the UV emitting disk and allow the line force to drive a disk wind. However the same X-ray radiation that inhibits line driving heats the disk and can produce a hot bipolar wind or corona above the disk. To assess the impact of X-ray heating upon driving of a disk wind by the line force in any system with an accretion disk we derive analytic formulae. In particular, we compare results of line-driven disk wind models for accretion disks in LMXBs and active galactic nuclei. The latter show spectral features associated with a strong and fast disk wind. The key parameter determining the role of the line force is not merely the presence of the luminous UV zone in the disk and the presence of the X-rays, but also the distance of this UV zone from the center.Comment: LaTeX, 34 pages, contains color figures, to appear in Ap

Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy

Adhesion to extracellular matrix (ECM) is crucially important for survival of normal epithelial cells as detachment from ECM triggers specific apoptosis known as anoikis. As tumor cells lose the requirement for anchorage to ECM, they rely on cell-cell adhesion 'multicellular aggregation' for survival. Multicellular aggregation of tumor cells also significantly determines the sensitivity of tumor cells to the cytotoxic effects of chemotherapeutics. In this report, we demonstrate that expression of immunoglobulin containing and proline-rich receptor-1 (IGPR-1) is upregulated in human primary colon cancer. Our study demonstrates that IGPR-1 promotes tumor multicellular aggregation, and interfering with its adhesive function inhibits multicellular aggregation and, increases cell death. IGPR-1 supports colon carcinoma tumor xenograft growth in mouse, and inhibiting its activity by shRNA or blocking antibody inhibits tumor growth. More importantly, IGPR-1 regulates sensitivity of tumor cells to the chemotherapeutic agent, doxorubicin/adriamycin by a mechanism that involves doxorubicin-induced AKT activation and phosphorylation of IGPR-1 at Ser220. Our findings offer novel insight into IGPR-1's role in colorectal tumor growth, tumor chemosensitivity, and as a possible novel anti-cancer target.Grant support from: R01 CA175382/CA/NCI NIH HHS/United States, R21 CA191970/CA/NCI NIH HHS/United States, and R21 CA193958/CA/NCI NIH HHS/United State

MCMC Exploration of Supermassive Black Hole Binary Inspirals

The Laser Interferometer Space Antenna will be able to detect the inspiral and merger of Super Massive Black Hole Binaries (SMBHBs) anywhere in the Universe. Standard matched filtering techniques can be used to detect and characterize these systems. Markov Chain Monte Carlo (MCMC) methods are ideally suited to this and other LISA data analysis problems as they are able to efficiently handle models with large dimensions. Here we compare the posterior parameter distributions derived by an MCMC algorithm with the distributions predicted by the Fisher information matrix. We find excellent agreement for the extrinsic parameters, while the Fisher matrix slightly overestimates errors in the intrinsic parameters.Comment: Submitted to CQG as a GWDAW-10 Conference Proceedings, 9 pages, 5 figures, Published Versio