2,197 research outputs found

    Trip Attraction Rates of Banking Services in Developing Countries' Cities

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    There is a lack of studies on trip generation rates related to land use activities in developing countries. The absence of trip rates makes transportation planners use rates listed in the Institute of Transportation Engineers (ITE) Trip Generation Manual, which may lead to unrealistic results. The study aims to determine trip attraction rates for banking services in Zagazig city, Egypt, and evaluate the factors affecting the attracted trips to the banks. The study has designed and implemented a comprehensive data collection and analysis program. The study sample contained nine banks. The study has conducted field surveys that counted the total number of persons entering/exiting the bank under investigation and the generated traffic volume of the adjacent street. The trip rates have been established in terms of independent variables, i.e., gross floor area, the total number of employees, and the number of tellers for different types of banks. Findings showed that average trip attraction rates for public banks were higher than for private banks. There was a strong relationship between trip attractions and the total number of employees at public banks. The most representative factor of private banks' trip attractions was the number of tellers. Doi: 10.28991/CEJ-2023-09-02-07 Full Text: PD

    Some entanglement features of three-atoms Tavis-Cummings model: Cooperative case

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    In this paper we consider a system of identical three two-level atoms interacting at resonance with a single-mode of the quantized field in a lossless cavity. The initial cavity field is prepared in the coherent state while the atoms are taken initially to be either in the uppermost excited state "∣eee>|eee>" or The GHZ\textmd{GHZ}-state or the W\textmd{W}-state. For this system we investigate different kinds of atomic inversion and entanglement, which arise between the different parts of the system due to the interaction. Also the relationship, between entanglement and some other nonclassical effects in the statistical properties, such as collapses and revivals in the atomic inversion where superharmonic effects appear, is discussed. The QQ-functions for different cases are discussed. Most remarkably it is found that the GHZ\textmd{GHZ}-state is more robust against energy losses, showing almost coherent trapping and Schr\"odinger-cat states can not be produced from such state. Also the entanglement of GHZ\textmd{GHZ}-state is more robust than the W\textmd{W}-state. Another interesting feature found is that the state which has no pairwise entanglement initially will have a much improvement of such pairwise entanglement through the evolution. Sudden death and sudden revival of atoms-pairwise entanglement are produced with the W\textmd{W}-state.Comment: 14 pages, 7 figure

    Endometrial scratch in women undergoing first-time IVF treatment : a systematic review and meta-analysis of randomized controlled trials

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    The endometrial scratch procedure is an IVF ‘add-on’ sometimes provided prior to the first IVF cycle. A 2019 systematic review concluded that there was insufficient evidence to show whether endometrial scratch has a significant effect on pregnancy outcomes (including live birth rate, LBR) when undertaken prior to the first IVF cycle. Further evidence was published following this review, including the Endometrial Scratch Trial (ISRCTN23800982). The objective of the current review was to synthesize and critically appraise the evidence for the clinical effectiveness and safety of the endometrial scratch procedure in women undergoing their first IVF cycle. Databases searched include MEDLINE, Embase, CINAHL and ClinicalTrials.gov. Eligible randomized controlled trials included women undergoing IVF for the first time that reported the effectiveness and/or safety of the endometrial scratch procedure; 12 studies were included. Meta-analysis showed no evidence of a significant effect of the endometrial scratch on LBR (10 trials, odds ratio [OR] 1.17, 95% confidence interval [CI] 0.76–1.79) or other pregnancy outcomes. This review confirms that there is a lack of evidence that endometrial scratch improves pregnancy outcomes, including LBR, for women undergoing their first IVF cycle. Clinicians are recommended not to perform this procedure in individuals undergoing their first cycle of IVF

    Enhancement of nonclassical properties of two qubits via deformed operators

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    We explore the dynamics of two atoms interacting with a cavity field via deformed operators. Properties of the asymptotic regularization of entanglement measures proving, for example, purity cost, regularized fidelity and accuracy of information transfer are analyzed. We show that the robustness of a bipartite system having a finite number of quantum states vanishes at finite photon numbers, for arbitrary interactions between its constituents and with cavity field. Finally it is shown that the stability of the purity and the fidelity is improved in the absence of the deformation parameters

    Experiences of trial participants and site staff of participating in and running a large randomised trial within fertility (the endometrial scratch trial): a qualitative interview study

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    Objectives To explore the experiences of endometrial scratch (ES) trial participants and site staff of trial recruitment and participation, in order to improve the experience of participants in future trials. Design Qualitative study of a subset of participants in the ES randomised controlled trial and a subset of trial site staff. Setting A purposeful sample of 9 of the 16 UK Fertility Units that participated in the trial. Participants A purposeful sample of 27 trial participants and 7 site staff. Results Participants were largely happy with the recruitment practices, however, some were overwhelmed with the amount of information received. Interviewees had positive preconceptions regarding the possible effect of the ES on the outcome of their in vitro fertilisation (IVF) cycle, which often originated from their own internet research and seemed to be exacerbated by how site staff described the intervention. Some participants appeared to not understand that receiving the ES could potentially reduce their chances of a successful IVF outcome. Those randomised to the control arm discussed feeling discontent; site staff developed mechanisms of dealing with this. Conclusions A lack of equipoise in both study participants and the recruiting site staff led to trial participants having positive preconceptions of the potential impact of the ES on their upcoming IVF cycle. Trial participants may not have understood the potential harms of participating in a randomised trial. The trial information sheet did not clearly state this; further research should assess how such information should be presented to potential participants, to proportionately present the level of risk, but to not unduly discourage participation. The amount of information fertility patients require about a research study should also be investigated, in order to avoid participants feeling overwhelmed by the amount of information they receive prior to starting IVF. Trial registration number ISRCTN23800982

    Risk factors for traumatic and non-traumatic lower limb pain among preadolescents: a population-based study of Finnish schoolchildren

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    BACKGROUND: The child's lower limb is the most commonly reported musculoskeletal location with pain and also the most commonly injured site in sports. Some potential risk factors have been studied, but the results are inconsistent. We hypothesized that distinction of traumatic from non-traumatic pain would provide a clearer picture of these factors. The aim of this study is to assess factors associated with lower extremity pain and its impact on preadolescents in a population-based cohort. METHODS: A structured pain questionnaire was completed by 1756 schoolchildren of third and fifth grades to assess musculoskeletal pain, psychosomatic symptoms, subjective disabilities, school absence and frequency of exercise. In addition, hypermobility and physical fitness were measured. RESULTS: The knee was the most common site of pain followed by the ankle-foot and thigh. Of the children who reported pain in their lower extremity, approximately 70% reported at least one disability and 19 % reported school absence attributed to their pain during the previous three-month period. Children with traumatic pain had a higher subjective disability index than those with non-traumatic pain (P = 0.02). Age less than 11 years, headache, abdominal pain, depressive feelings, day tiredness, and vigorous exercise were more common in children with lower limb pain than those free of it. In the stratified analysis, younger age was related to both traumatic and non-traumatic pain groups. Vigorous exercise was positively associated with traumatic pain, while subjects with non-traumatic pain had more frequent psychosomatic symptoms. CONCLUSION: Risk factors and consequences of traumatic and non-traumatic lower limb pain are not similar. Traumatic lower limb pain is associated with practicing vigorous exercise and high level of physical fitness, while non-traumatic pain is more correlated with psychosomatic symptoms. These differences might be one of the reasons for the discrepancy of previous research conclusions. The two conditions need to be treated as different disorders in future studies

    Dual proteotoxic stress accelerates liver injury via activation of p62-Nrf2

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    Protein accumulation is the hallmark of various neuronal, muscular, and other human disorders. It is also often seen in the liver as a major protein-secretory organ. For example, aggregation of mutated alpha1-antitrypsin (AAT), referred to as PiZ, is a characteristic feature of AAT deficiency, whereas retention of hepatitis B surface protein (HBs) is found in chronic hepatitis B (CHB) infection. We investigated the interaction of both proteotoxic stresses in humans and mice. Animals overexpressing both PiZ and HBs (HBs-PiZ mice) had greater liver injury, steatosis, and fibrosis. Later they exhibited higher hepatocellular carcinoma load and a more aggressive tumor subtype. Although PiZ and HBs displayed differing solubility properties and distinct distribution patterns, HBs-PiZ animals manifested retention of AAT/HBs in the degradatory pathway and a marked accumulation of the autophagy adaptor p62. Isolation of p62-containing particles revealed retained HBs/AAT and the lipophagy adapter perilipin-2. p62 build-up led to activation of the p62–Nrf2 axis and emergence of reactive oxygen species. Our results demonstrate that the simultaneous presence of two prevalent proteotoxic stresses promotes the development of liver injury due to protein retention and activation of the p62–Nrf2 axis. In humans, the PiZ variant was over-represented in CHB patients with advanced liver fibrosis (unadjusted odds ratio = 9.92 [1.15–85.39]). Current siRNA approaches targeting HBs/AAT should be considered for these individuals. © 2021 The Authors. The Journal of Pathology published by John Wiley & Sons, Ltd. on behalf of The Pathological Society of Great Britain and Ireland
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