9 research outputs found

    On upper and lower D_delta-supercontinuous multifunctions

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    Upper and Lower Continuity of Soft Multifunctions

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    In this paper, we introduced the notion of soft multifunctions and define the upper and lower inverse of a soft multifunction and prove basic properties. Then using these ideas we introduced the concepts of upper and lower continuous soft multifunctions. Also we obtain some characterizations and several properties concerning upper and lower soft continuous multifunctions

    On Soft β-Open Sets and Soft β-Continuous Functions

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    We introduce the concepts soft β-interior and soft β-closure of a soft set in soft topological spaces. We also study soft β-continuous functions and discuss their relations with soft continuous and other weaker forms of soft continuous functions

    Inflammatory status might direct ILC and NK cells to IL-17 expressing ILC3 and NK subsets in Behcet's disease.

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    Innate lymphoid cells (ILCs) are lymphoid cells that have important effector and regulatory functions in innate immunity and tissue remodeling. Uncontrolled activation and proliferation of ILCs can contribute to inflammatory autoimmune diseases. Behcet's disease (BD) is a complex systemic inflammatory disorder of unknown etiology. It has been shown that natural killer (NK) cells may play an immunoregulatory role in BD, however the role of ILCs is unknown. In this study, the levels and functions of ILCs and NK cell subsets in BD patients were investigated. Cell surface and cytotoxic granules (perforM and granzyme) expression of NK cells and ILCs were evaluated and labeled according to whole blood lysing protocol in peripheral blood samples obtained from the patients and healthy subjects. Cytokine levels of NK cells were investigated in stimulated peripheral blood mononuclear cells. All data were analyzed by flow cytometry. Total ILC and ILC3(+) cells were increased in active BD patients compared to inactive BD patients and healthy subjects. There was no significant difference between the patients and healthy subjects regarding NK cell surface and intracellular molecule expression. Although, an increase in IFN-gamma and IL-17, and a decrease in IL-4 levels were observed in CD56(dim) NK cell subset of BD patients. Recent studies showed increased neutrophilic infiltration and IL-17 secreting Th17 cells in BD patients. It is known that ILC3(+ )cells are similar to Th17 subset regarding their cytokine profile and transcription factor expression patterns. Results of current study may suggest that inflammatory microenvironment in BD patients might direct ILC cells to differentiate into ILC3(+) subset, and IL-17 released by NK cells might have a role in neutrophilic infiltration

    mRNA Expression Levels of NKp30, NKp46, NKG2D, Perforin and Granzyme in the Behcet's Disease

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    Objective: There are limited studies about NK cells that may have an immunoregulatory role in Behcet's Disease. NK cell receptor, perforin and granzyme mRNA expressions were analyzed in both Wive and inactive BD patients

    Current Statement of Intensive Care Units in Turkey: Data obtained from 67 Centers

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    OBJECTIVES: We aimed to obtain information about the characteristics of the ICUs in our country via a point prevalence study

    TÜRKİYE’DE YOĞUN BAKIM ÜNİTELERİNDE VENTİLATÖR İLİŞKİLİ PNÖMONİYİ ÖNLEMEK IÇIN ALINAN GÜNCEL ÖNLEMLER: TÜRK TORAK DERNEĞİ SOLUNUM YETMEZLİĞİ VE YOĞUN BAKIM ÇALIŞMA GRUBU NOKTA PREVALANS ÇALIŞMASI

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