3-(4-Nitro­phen­yl)-N-phenyl­oxirane-2-carboxamide

The mol­ecule of the title compound, C15H12N2O4, adopts a syn conformation with the terminal benzene rings located on the same sides of the central epoxide ring. The epoxide ring makes dihedral angles of 71.08 (18) and 60.83 (17)° with the two benzene rings. Weak inter­molecular C—H⋯O hydrogen bonding is present in the crystal structure

2-Chloro-3-hydroxy­methyl-6-methoxy­quinoline

All the non-H atoms of the title compound, C11H10ClNO2, are roughly coplanar (r.m.s. deviation = 0.058 Å). In the crystal, adjacent mol­ecules are linked by an O—H⋯N hydrogen bond, generating chains running along the a axis

2-Phenyl­imidazo[1,2-a]pyridine-3-carbaldehyde

In the title compound, C14H10N2O, the dihedral angle between the imidazo[1,2-a]pyridine and phenyl rings is 28.61 (4)° The mol­ecules are connected into broad chains parallel to the a axis by weak C—H⋯O and C—H⋯N hydrogen bonds. The linking of the ribbons is provided by π–π stacking inter­actions between neighbouring pyridine rings, with a centroid–centroid distance of 3.7187 (7) Å

(2E)-3-(2-Chloro-6-methyl-3-quinol­yl)-1-(1-naphth­yl)prop-2-en-1-one

In the title mol­ecule, C23H16ClNO, the quinoline and naphthalene ring systems are individually planar, with maximum deviations of 0.020 (2) and 0.033 (2) Å, respectively, and are inclined at a dihedral angle of 30.01 (4)°. Intra­molecular C—H⋯O and C—H⋯Cl inter­actions occur. The crystal structure is devoid of any classical hydrogen bonds, but symmetry-related mol­ecules are linked via weak C—H⋯Cl inter­actions, forming chains propagating in [001]

4-[(Dimethyl­amino)methyl­idene]-2-(4-nitro­phen­yl)-1,3-oxazol-5(4H)-one

The title mol­ecule, C12H11N3O4, is essentially planar, the r.m.s. deviation for all non-H atoms being 0.068 Å. An intra­molecular C—H⋯N hydrogen bond occurs. The crystal packing is dominated by π–π inter­actions [shortest centroid–centroid distance = 3.6312 (16) Å], which lead to supra­molecular chains that are linked into a three-dimensional network via C—H⋯O contacts. The crystal was found to be a non-merohedral twin (twin law −1 0 0/0 −1 0/ 0.784 0 1), the fractional contribution of the minor component being approx­imately 22%

N-[(2-Chloro-3-quinol­yl)meth­yl]-4-fluoro­aniline

In the title compound, C16H12ClFN2, the dihedral angle between the quinoline ring system and the flourophenyl ring is 86.70 (4)°. In the crystal, mol­ecules are linked into chains along the a axis by N—H⋯N hydrogen bonds. In addition, C—H⋯π inter­actions involving the two benzene rings are observed

The diastereoselective Meth-Cohn epoxidation of camphor-derived vinyl sulfones

Some camphor-derived vinyl sulfones bearing oxygen functionality at the allylic position have been synthesized and their nucleophilic epoxidation reactions under Meth-Cohn conditions have been explored. The γ-oxygenated camphor-derived vinyl sulfones underwent mildly diastereoselective nucleophilic epoxidation reactions, affording the derived sulfonyloxiranes in up to 5.8:1 dr. The observed diastereoselectivities were sensitive to the reaction conditions employed. In contrast, no stereoselectivity was observed in the nucleophilic epoxidation of the corresponding γ-oxygenated isobornyl vinyl sulfone. A tentative mechanism has been proposed to explain the origins of the diastereoselectivit