Development of a methodology for sustainable product re-design from product architecture principles

Sustainability is one of the most trending topics in the world due to the increase of interest regarding environmental, economical and social issues for future generations. In the field of product design, it is possible to identify research opportunities focused on the development of design methods for more sustainable products. Reuse, remanufacture and recycle are considered key issues for including sustainability in the entire lifecycle of products. From the design perspective, Product architecture principles provide huge benefits from early design stages, specially in the definition of components for product families, which entails the use of common components or modules able to be reused along different product versions or variants. This work, proposes a product re-design methodology for product families, taking into account the need for modularizing components to improve sustainability and functional performance. An adaptation of the four-stage design method is proposed, including additional steps to generate products that offer a better sustainability performance. A family of prosthetic devices for children is employed as case study to demonstrate the application and benefits of the proposed approach. The case study is re-designed to generate an open architecture product family. A set of proposed indicators is used to compare the sustainability performance of both, original and open architecture product family

Desarrollo de una metodología para el diseño conceptual de sistemas reconfigurables de fabricación (RMS) a partir de modularidad

Los constantes cambios en requerimientos de los clientes en segmentos de mercado y la necesidad de adaptabilidad en el diseño y fabricación de productos conllevan a la utilización del concepto de sistemas reconfigurables de fabricación (RMS), los cuales involucran el uso de modularidad y permiten con una cantidad limitada de recursos adaptar la fabricación y algunos aspectos del ciclo de vida con la reconfiguración. En este trabajo se muestra una metodología de diseño modificada y ajustada a sistemas con requerimientos de reconfiguración desde el diseño conceptual. Esta metodología permite establecer y diferenciar funcionalidades que requieren reconfiguración y que pueden optimizarse mediante el uso de módulos, los cuales ofrecen ventajas a lo largo del ciclo de vida del producto. La metodología propuesta es validada sobre una máquina ensambladora de intercambiadores de calor compactos de aluminio, sin embargo puede ser aplicable a cualquier producto con variación de requerimientos o rangos de trabajo en funciones específicas

Associated factors for mortality in a COVID-19 colombian cohort : is the third wave relevant when Mu variant was predominant epidemiologically?

Q1Q1Pacientes con COVID-19Objectives: To evaluate the association between Colombia's third wave when the Mu variant was predominant epidemiologically (until 75%) in Colombia and COVID-19 all-cause in-hospital mortality. Methods: In this retrospective cohort, we included hospitalized patients ≥18 years with SARS-CoV-2 infection between March 2020 to September 2021 in ten hospitals from three cities in Colombia. Description analysis, survival, and multivariate Cox regression analyses were performed to evaluate the association between the third epidemic wave and in-hospital mortality. Results: A total of 25,371 patients were included. The age-stratified time-to-mortality curves showed differences according to epidemic waves in patients ≥75 years (log-rank test p = 0.012). In the multivariate Cox analysis, the third wave was not associated with increased mortality relative to the first wave (aHR 0.95; 95%CI 0.84–1.08), but there was an interaction between age ≥75 years and the third wave finding a lower HR for mortality (aHR 0.56, 95%CI 0.36–0.86). Conclusions: We did not find an increase in in-hospital mortality during the third epidemic wave in which the Mu variant was predominant in Colombia. The reduced hazard in mortality in patients ≥75 years hospitalized in the third wave could be explained by the high coverage of SARS-CoV-2 vaccination in this population and patients with underlying conditions.https://orcid.org/0000-0003-1833-1599https://orcid.org/0000-0001-5363-5729https://orcid.org/0000-0001-6964-2229https://orcid.org/0000-0003-3975-2835https://orcid.org/0000-0001-9441-4375Revista Internacional - IndexadaA1N

Revista Temas Agrarios Volumen 26; Suplemento 1 de 2021

1st International and 2nd National Symposium of Agronomic Sciences: The rebirth of the scientific discussion space for the Colombian Agro.1 Simposio Intenacional y 2 Nacional de Ciencias Agronómicas: El renacer del espacio de discusión científica para el Agro colombiano