2-Hy­droxy­methyl-1,3-dimethyl­imidazolium iodide

The crystal packing of the title compound, C6H11N2O+·I−, can be described as inter­calated layers lying parallel to (010), with the iodide ions located between the cations. A weak intra­molecular C—H⋯O hydrogen bond occurs within the cation. In the crystal, inter­molecular O—H⋯I hydrogen bonds result in the formation of a three-dimensional network and reinforce the cohesion of the ionic structure

2-(4-Chlorophenyl)-2,3-dihydroquinolin-4(1H)-one

The title molecule, C15H12ClNO, features a dihydroquinolin-4(1H)-one moiety attached to a chlorobenzene ring. The heterocyclic ring has a half-chair conformation with the methine C atom lying 0.574 (3) Å above the plane of the five remaining atoms (r.m.s. deviation = 0.0240 Å). The dihedral angles between the terminal benzene rings is 77.53 (9)°, indicating a significant twist in the molecule. In the crystal, supramolecular zigzag chains along the c-axis direction are sustained by N—H...O hydrogen bonds. These are connected into double chains by C—H...π interactions

2-p-Tolyl-2,3-dihydroquinolin-4(1H)-one

In the title molecule, C16H15NO, the tetrahydropyridine ring is in a sofa conformation with the methine C atom forming the flap. The dihedral angle between the benzene rings is 80.85 (8)°. In the crystal, molecules are arranged in alternating double layers parallel to (100) and are connected along [001] by N—H...O hydrogen bonds. In addition, weak C—H...π interactions are observed

Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus

International audienceSeveral new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds