2D Spectroscopy of Candidate Polar-Ring Galaxies: I. The Pair of Galaxies UGC 5600/09

Observations of the pair of galaxies VV 330 with the SCORPIO multimode instrument on the 6-m Special Astrophysical Observatory telescope are presented. Large-scale velocity fields of the ionized gas in H-alfa and brightness distributions in continuum and H-alfa have been constructed for both galaxies with the help of a scanning Fabry Perot interferometer. Long-slit spectroscopy is used to study the stellar kinematics. Analysis of the data obtained has revealed a complex structure in each of the pair components. Three kinematic subsystems have been identified in UGC 5600: a stellar disk, an inner gas ring turned with respect to the disk through ~80degrees, and an outer gas disk. The stellar and outer gas disks are noncoplanar. Possible scenarios for the formation of the observed multicomponent kinematic galactic structure are considered, including the case where the large-scale velocity field of the gas is represented by the kinematic model of a disk with a warp. The velocity field in the second galaxy of the pair, UGC 5609, is more regular. A joint analysis of the data on the photometric structure and the velocity field has shown that this is probably a late-type spiral galaxy whose shape is distorted by the gravitational interaction, possibly, with UGC 5600.Comment: 18 pages, 6 figure

Study of the structure and kinematics of the NGC 7465/64/63 triplet galaxies

This paper is devoted to the analysis of new observational data for the group of galaxies NGC 7465/64/63, which were obtained at the 6-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences (SAO RAS) with the multimode instrument SCORPIO and the Multi Pupil Fiber Spectrograph. For one of group members (NGC 7465) the presence of a polar ring was suspected. Large-scale brightness distributions, velocity and velocity dispersion fields of the ionized gas for all three galaxies as well as line-of-sight velocity curves on the basis of emission and absorption lines and a stellar velocity field in the central region for NGC 7465 were constructed. As a result of the analysis of the obtained information, we revealed an inner stellar disk (r ~ 0.5 kpc) and a warped gaseous disk in addition to the main stellar disk, in NGC 7465. On the basis of the joint study of photometric and spectral data it was ascertained that NGC 7464 is the irregular galaxy of the IrrI type, whose structural and kinematic peculiarities resulted most likely from the gravitational interaction with NGC 7465. The velocity field of the ionized gas of NGC 7463 turned out typical for spiral galaxies with a bar, and the bending of outer parts of its disk could arise owing to the close encounter with one of galaxies of the environment.Comment: 20 pages, 6 figure

ОСОБЛИВОСТІ ПОРУШЕННЯ СИСТЕМИ ГЕМОСТАЗУ У ХВОРИХ НА КОРОНАВІРУСНУ ІНФЕКЦІЮ

The aim of the work – to analyze the features of hemostasis disorders in patients with coronavirus infection. Materials and methods. 78 medical records of inpatients hospitalized in the Regional Clinical Infectious Diseases Hospital of Kharkiv for the period from May to September 2020 were analyzed. To assess the state of the hemostasis system and the risk of thrombohemorrhagic complications, the level of platelets, fibrinogen, D-dimer, active partial thromboplastic time (APTT), international normalized ratio (INR) was monitored. Results. During the study, disorders of cellular and plasma indicators of hemostasis were analyzed. Patients were divided into groups, depending on the severity of respiratory failure. Coagulation tests were monitored every 48 hours. Conclusion. In patients with moderate severity, disorders of the hemostasis system in the form of hypercoagulation prevailed. Prolonged course of the disease for more than 21 days or in patients with severe, extremely severe course, hypercoagulation changed to hypocoagulation and DIC syndrome occurred. There is a direct relationship with the state of hemostasis and the severity of coronavirus infection.Мета роботи – проаналізувати особливості порушення системи гемостазу у хворих на коронавірусну інфекцію. Матеріали та методи. Проаналізовано 78 медичних карт стаціонарних хворих, госпіталізованих в обласну клінічну інфекційну лікарню м. Харкова за період з травня по вересень 2020 р. Для оцінки стану системи гемостазу та ризику виникнення тромбогеморагічних ускладнень проводили моніторинг рівня тромбоцитів, фібриногену, D-димеру, активного часткового тромбопластинового часу (АЧТЧ), міжнародного нормалізованого відношення (МНВ). Результати дослідження. Під час дослідження були проаналізовані порушення клітинних і плазматичних показників гемостазу. Хворі були поділені на групи, залежно від ступеня тяжкості дихальної недостатності. Моніторинг коагуляційних тестів проводили кожні 48 год. Висновок. У пацієнтів із середнім ступенем тяжкості переважали порушення системи гемостазу у вигляді гіперкоагуляції. Тривалий перебіг хвороби понад 21 добу або у хворих із тяжким чи вкрай тяжким ступенем гіперкоагуляція змінювалася на гіпокоагуляцію та виникав ДВЗ-синдром. Показники гемостазу прямо корелювали зі ступенем тяжкості коронавірусної інфекції

The combination of traditional cardiorespiratory markers during treadmill testing “to failure” in athletes, depending on professional activity

Exercise tolerance test with the use of the spiroergometry technique is a reliable diagnostic method which provides objective information about cardiorespiratory system condition when performing physical activity. Both new and traditional, well-proven cardiorespiratory markers obtained in the process of treadmill testing “to failure”, are described in this article. The nature of the influence of physical exertion on the indicators of cardiorespiratory system functional activity is presented. The interpretation for planning and subsequent monitoring of the training process in athletes of various professional activities is proposed

Prevention of Cardioembolic Complications in Patients with Atrial Fibrillation: Efficacy and Safety of Left Atrial Appendage Isolation and Oral Anticoagulants

Aim. To study the outcomes frequency and structure in patients with atrial fibrillation (AF) depending on the cardioembolic events preventing method: left atrial appendage (LAA) isolation, direct oral anticoagulants (DOACs) or warfarin.Material and methods. A prospective observational study included patients with AF and high risk of cardioembolic complications and without contraindications to anticoagulants. Patients who refused long-term oral anticoagulants taking underwent LAA isolation, the rest of the patients received DOACs or warfarin. The observation period was 3 years. Mortality, cardioembolic complications and major bleeding (according to GARFIELD criteria) cumulative incidence was assessed.Results. We included 245 patients: 46 patients were treated with LAA isolation, 100 with warfarin, and 99 with DOACs. Multivariate regression analysis demonstrated a statistically significant advantage of LAA occluder in terms of combined endpoint achieving frequency compared to warfarin (hazard ratio [HR] 3.10; 95% confidence interval [CI] 1.01-9.54; p=0.049), and to DOACs (HR 3.44, 95% CI 1.15-10.29; p=0.027). A similar result was obtained for all-cause mortality (HR 5.24; 95% CI 1.12-24.55; p=0.036 and HR 5.58; 95% CI 1.22-25.49; p=0.027, respectively). There were no significant differences in bleeding rates between the groups.Conclusion. This observational study demonstrates the superiority of LAA isolation as a first-line therapy over DOACs and warfarin in patients with AF and high risk of cardioembolic complications. Randomized trials are required to confirm these observations

Steps Toward Determination of the Size and Structure of the Broad-Line Region in Active Galactic Nuclei. XVI. A Thirteen-Year Study of Spectral Variability in NGC 5548

We present the final installment of an intensive 13-year study of variations of the optical continuum and broad H-beta emission line in the Seyfert 1 galaxy NGC 5548. The data base consists of 1530 optical continuum measurements and 1248 H-beta measurements. The H-beta variations follow the continuum variations closely, with a typical time delay of about 20 days. However, a year-by-year analysis shows that the magnitude of emission-line time delay is correlated with the mean continuum flux. We argue that the data are consistent with the simple model prediction that the size of the broad-line region is proportional to the square root of the ionizing luminosity. Moreover, the apparently linear nature of the correlation between the H-beta response time and the nonstellar optical continuum arises as a consequence of the changing shape of the continuum as it varies, specifically with the optical (5100 A) continuum luminosity proportional to the ultraviolet (1350 A) continuum luminosity to the 0.56 power.Comment: 20 pages plus 4 figures. Accepted for publication in The Astrophysical Journa

A dust-parallax distance of 19 megaparsecs to the supermassive black hole in NGC 4151

The active galaxy NGC 4151 has a crucial role as one of only two active galactic nuclei for which black hole mass measurements based on emission line reverberation mapping can be calibrated against other dynamical methods. Unfortunately, effective calibration requires an accurate distance to NGC 4151, which is currently not available. Recently reported distances range from 4 to 29 megaparsecs (Mpc). Strong peculiar motions make a redshift-based distance very uncertain, and the geometry of the galaxy and its nucleus prohibit accurate measurements using other techniques. Here we report a dust-parallax distance to NGC 4151 of $D_A = 19.0^{+2.4}_{-2.6}$ Mpc. The measurement is based on an adaptation of a geometric method proposed previously using the emission line regions of active galaxies. Since this region is too small for current imaging capabilities, we use instead the ratio of the physical-to-angular sizes of the more extended hot dust emission as determined from time-delays and infrared interferometry. This new distance leads to an approximately 1.4-fold increase in the dynamical black hole mass, implying a corresponding correction to emission line reverberation masses of black holes if they are calibrated against the two objects with additional dynamical masses.Comment: Authors' version of a letter published in Nature (27 November 2014); 8 pages, 5 figures, 1 tabl

EFFECT AUTOMOBILE WHEEL RIM ROLLING DISK OF SILICONE ON ITS STRUCTURE AND MECHANICAL PROPERTIES

Исследованы микроструктура и механические свойства литых дисков автомобильных колес из силумина марки АК7 после раскатки обода. В результате деформации и последующей термической обработки достигнуто повышение механических свойств.The microstructure and mechanical properties of cast wheel discs from silumin brand AK7 after rolling the rim. As a result, deformation and subsequent heat treatment achieved improvement in the mechanical properties

Сравнение вариантов анестезиологического обеспечения имплантации окклюдера ушка левого предсердия у пациентов с фибрилляцией предсердий

Objective: comparison of general anesthesia (GA) and intravenous conscious sedation during left atrial appendage occlusion (LAAO).Materials and Methods. The study included 120 patients from LAAO Register at the National Medical Research Center of Cardiology, who were divided into GA (n = 100) and intravenous sedation (n = 20) groups. In-hospital outcomes were assessed, as well as outcomes and data of transesophageal echocardiography (TEE) at 45 days and 6 months.Results. 3 patients required intraoperative conversion of the anesthetic method to GA. The duration of the procedure, the time of fluoroscopy, the amount of contrast medium, and the technical success did not differ signifcantly between the two groups. The incidence of in-hospital complications in the GA group was 10%, and 15% in the intravenous sedation group (p = 0.453). There were no statistically signifcant differences between the groups in long-term outcomes and TEE data after 45 days and 6 months.Conclusion. Combined intravenous sedation with local anesthesia is an effective and fairly safe method of anesthesiological support for implantation of the occluder of the left atrial auricle. It can be used in patients with a high risk of GA, with predictable difculties of tracheal intubation, as well as if the patient wishes accordingly. The limitations of the use of intravenous sedation in combination with local anesthesia are anatomical variants of SFM that are difcult for occluder implantation, as well as the patient's low tolerance to ECG in consciousness.Цель: сравнение вариантов анестезиологического обеспечения – общей анестезии (ОА) и внутривенной седации при имплантации окклюдера ушка левого предсердия (УЛП).Материалы и методы. В исследование включено 120 пациентов из регистра имплантации окклюдеров УЛП НМИЦ кардиологии, которые разделены на две группы с учетом использованной тактики анестезиологического обеспечения: ОА (n = 100) и внутривенной седации (n = 20). Оценивали внутригоспитальные исходы, а также исходы и данные чреспищеводной эхокардиографии (ЧПЭхоКГ) через 45 дней и 6 мес.Результаты: 3 пациентам понадобилась интраоперационная конверсия метода анестезии. Длительность процедуры, время флюороскопии, количество контраста, технический успех статистически значимо не различались между двумя группами. Частота внутригоспитальных осложнений в группе ОА составила 10%, а в группе внутривенной седации – 15% (p = 0,453). При оценке отдаленных исходов через 45 дней и 6 мес. статистически значимых различий между группами не выявлялось.Заключение. Сочетанная внутривенная седация с местной анестезией является эффективной и достаточно безопасной методикой анестезиологического обеспечения имплантации окклюдера УЛП. Ее можно применять у пациентов с высоким риском ОА, при предсказуемых трудностях интубации трахеи, а также при соответствующем желании пациента. Ограничениями применения внутривенной седации в сочетании с местной анестезией являются трудные для имплантации окклюдера анатомические варианты УЛП, а также низкая толерантность пациента к ЧПЭхоКГ в сознании

СОПОСТАВЛЕНИЕ РЕЗУЛЬТАТОВ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ И ВНУТРИСОСУДИСТОГО УЛЬТРАЗВУКОВОГО ИССЛЕДОВАНИЯ В ОЦЕНКЕ ПАРАМЕТРОВ АТЕРОСКЛЕРОТИЧЕСКИХ БЛЯШЕК КОРОНАРНЫХ АРТЕРИЙ

Purpose. To determine the possibilities of coronary CT-angiography (CTA) in evaluation of qualitative and qualitative parameters of coronary plaques in comparison with intravascular ultrasound (IVUS).Matherials and methods. 37 patients (29 men, 8 women) with symptoms of acute coronary syndrome (ACS) were included in the study. Unstable angina was detected in 24 patients, acute myocardial infarction (AMI) – in 13 patients. Averageage was 58 [44; 65] years. CTA had been performed as the first method of beam diagnostics in all cases if it was not necessary to use the emergency selective coronary angiography (CAG). IVUS was performed in one, two or three coronary arteries of every patient. Total, 60 coronary lesionsin 55 arteries were examined with IVUS. IVUS data was compared with CTA data.Results. Methods well correlated in detection of plaque burden (r = 0.823; p < 0.0001), plaque length (r = 0.932, p < 0.0001), remodeling index(RI) (r = 0.906; p < 0.0001). Sensitivity and specificity of CTA in detection of irregular contour was 96.1% and 88.9% (area under ROC-curve 0.925), positive remodeling – 100% and 97.4% (area under ROC-curve 0.974). CTA and IVUS in evaluation of spotty calcinates was not coincide in 9 plaques, sensitivity and specificity of CTA in detection of 71% and 100% (area under ROC-curve 0.855).Discussion. Comparison of CTA and IVUS was performed in evaluation of plaques features in patients with ACS. This analysis showed high comparability of methods for evaluation of coronary stenosis degree, RI, plaque burden, length and contour. Thus, the characteristics of plaques according to CTA data can be used to stratify the risk of development of ACS.Conclusion. CTA – fast non-invasive method of coronary plaques evaluation. CTA correlates well with IVUS.Цель исследования: определить возможности КТ-ангиографии (КТА) в оценке количественных и качественных характеристик атеросклеротических бляшек (АСБ) в коронарных артериях по сравнению с данными внутрисосудистого ультразвукового исследования (ВСУЗИ).Материал и методы. В исследование было включено 37 пациентов (29 мужчин, 8 женщин), поступивших в отделение неотложной кардиологии с клинической картиной острого коронарного синдрома (ОКС), из которых у 24 диагностирована нестабильная стенокардия, у 13 – острый инфаркт миокарда. Средний возраст больных составил 58 [44; 65] лет. Всем пациентам первым из лучевых методов исследования была выполнена КТА коронарных артерий при отсутствии необходимости экстренного проведения инвазивной коронарной ангиографии. Каждому из 37 пациентов ВСУЗИ было выполнено в одной, двух или трех коронарных артериях. Всего с помощью ВСУЗИ обследовано 60 измененных участков в 55 коронарных артериях. Данные ВСУЗИ сравнивались с результатами КТА.Результаты. Корреляционный анализ показал высокую сопоставимость методов в определении бремени бляшки (r = 0,823; p < 0,0001), протяженности бляшки (r = 0,932; p < 0,0001), индекса ремоделирования (ИР) (r = 0,906; p < 0,0001). Чувствительность и специфичность метода в выявлении неровности контура составили 96,1 и 88,9% (площадь под кривой 0,925), положительного ремоделирования – 100 и 97,4% (площадь под кривой 0,974) соответственно. При оценке точечных кальцинатов в 9 мягких бляшках данные КТА не совпадали с данными ВСУЗИ. а чувствительность и специфичность метода составили 71 и 100% (площадь под кривой 0,855) соответственно.Обсуждение. В представленной работе впервые в нашей стране проведен сравнительный анализ состояния бляшек в коронарных артериях по данным КТА и ВСУЗИ у больных с ОКС, который показал высокую сопоставимость методов для определения степени стенозирования просвета коронарных артерий, ИР, бремени, протяженности и контуров бляшки. Таким образом, характеристики АСБ по данным КТА можно использовать для стратификации риска развития ОКС.Заключение. КТА является быстрым неинвазивным методом оценки состояния АСБ. Результаты КТА хорошо коррелируют с данными ВСУЗИ