Highly regio- and diastereoselective oxazol-5-one addition to nitrostyrenes

A convenient and novel oxazol-5-one addition to nitrostyrenes is reported. The reaction is catalyzed by tertiary amines and yields the corresponding adducts with total regio- and diastereoselectivity. The addition exclusively takes place at the C-2 position of oxazol-5-ones, furnishing diastereopure N,O-aminals

Enantioselective addition of oxazolones to maleimides. An easy entry to quaternary aminoacids

The catalytic enantioselective addition of 2-tert-butyl-4-aryl-1,3-oxazol-5-ones to maleimides is reported. The addition takes place exclusively at the C-4 position of the oxazolone ring, giving access to quaternary amino acid derivatives. The reaction is catalyzed by readily available chiral bases such as (DHQD)2PYR, rendering the final compounds in good yields and with moderate to good diastereo- and enantioselectivities. When the C-4-substituent of the 2-tert-butyl-oxazolone is an alkyl group, the regioisomeric C-2 addition product is also obtained.<br/

Syntheses, Structure and Magnetic Properties of the Firstµ1,5-Dicyanamido-Bridged Dinuclear Compounds [Ni(µ1,5-dca)(dca)(dpt)]2 and [Ni(µ1,5-dca)(dca)(medpt)]2

10nonenoneDebajyoti Ghoshal;Hanna Bialas;Albert Escuer;Mercé Font-Bardía;Tapas Kumar Maji;Joan Ribas;Xavier Solans;Ramon Vicente;Ennio Zangrando;Nirmalendu Ray ChaudhuriDebajyoti, Ghoshal; Hanna, Bialas; Albert, Escuer; Mercé Font, Bardía; Tapas kumar, Maji; Joan, Ribas; Xavier, Solans; Ramon, Vicente; Zangrando, Ennio; Nirmalendu ray, Chaudhur

Enantioselective organocatalytic asymmetric allylic alkylation. Bis(phenylsulfonyl)methane addition to MBH carbonates

The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with bis(phenylsulfonyl)methane is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and enantioselectivities