Comparison of the Postoperative Mucociliary Clearance Time Between Patients who Underwent Septoplasty with and Without Nasal Packing

Objective:To compare the postoperative mucociliary clearance time in septoplasty with and without nasal packing.Methods:Forty-six patients with nasal septal deviation (20 women, 26 men) were assessed in this study. The patients underwent septoplasty under local anaesthesia. Patients were divided in two groups. Merocell® nasal packing was performed in both of the nasal passages for septum stabilization in the first group (28 patients). On the second postoperative day nasal packing was removed and salin irrigation solution was started. Transseptal suturing was performed for nasal stabilization in the second group and at the sixth postoperative hour saline irrigation solution was started. Saccarine clearance test was performed preoperatively and postoperatively at the 7th day, and 3th month and the results were compared.Results:In the treatment of 46 patients with a mean age of 20-53, in the first group; preoperative mucociliary clearance time on the deviated side was 12.2 minutes and on the opposite side was 13.1 minutes. In the second group, preoperative mucociliary clearance time on the deviated side was 11.9 minutes, and on the opposite side 12.8 minutes. In the first group, the postoperative 1th week mucociliary clearance time on the deviated side was 12.5 minutes and on the opposite side was 13.2 minutes and in the second group on the deviated side was 10.1 minutes, and on the opposite side was 10.8 minutes. In the first group, at the postoperative 3th month mucociliary clearance time on the deviated side was 11.6 minutes and on the opposite side was 11.4 minutes while in the second group on the deviated side was 6.7 minutes, and on the opposite side was 7.8 minutes.Conclusion:The postoperative mucociliary clearance time in patients treated for septal deviation were evaluated. We have determined that the mucociliary clearance time was longer in the patients that underwent septoplasty with nasal packing

D-galaktoz ile oluşturulmuş yaşlanma modelinde doku faktörü aktivitesinin ve sialik asit miktarının değerlendirilmesi

D-galaktoz ile oluşturulmuş yaşlanma modelinde doku faktörü aktivitesinin ve sialik asit miktarının değerlendirilmes

Interaction of Cocaine- and Amphetamine-regulated Transcript and Neuropeptide Y on Behavior in the Central Nervous System

Introduction: In the central nervous system, cocaine- and amphetamine-regulated transcript (CART) 55-102 peptide is localized in areas, such as the ventral tegmental area, amygdala, hypothalamus, and hippocampus, where emotional activity is regulated. Studies on the effects of the intracerebroventricular (ICV) administration of CART peptide on behavior remain limited. The findings from these studies suggest that this neuropeptide has anxiogenic-like effects. In the central nervous system, neuropeptide Y (NPY) has similar localization as CART. Previous behavioral studies have demonstrated that the ICV administration of NPY has anxiolytic-like effects

The effects of intracerebroventricular NPY application on the general emotional activity in rats exposed to chronic immobilization stress

Objective: It has been shown that Neuropeptide Y (NPY) has anxiolytic effects in behavioural studies and has anti-stressor activity during acute stress. In this study, we examined the effects of intracerebroventricular (ICV) NPY application on the general emotional activity in rats exposed to chronic immobilization stress