Vehículo Aéreo No Tripulado (VANT) para conservación de Áreas Silvestres Protegidas (ASPs) del Paraguay

Se presenta el desarrollo de un modelo de vehículo aéreo no tripulado pequeño de bajo costo, con integración de aplicaciones para la conservación de las Áreas Silvestres Protegidas.CONACYT - Consejo Nacional de Ciencias y TecnologíaPROCIENCI

Vehículo Aéreo No Tripulado (VANT) una Herramienta para la Conservación de las Áreas Silvestres Protegidas del Paraguay (ASPs)

La falta de recursos humanos y logísticos dificultan en gran medida las actividades de monitoreo de Áreas Silvestres Protegidas tanto en áreas públicas como privadas. La utilización de vehículos aéreos no tripulados (VANT) como herramientas para el monitoreo podría complementar el trabajo de los guardaparques en las labores de patrullaje, especialmente en áreas remotas o de difícil acceso.CONACYT – Consejo Nacional de Ciencia y TecnologíaPROCIENCI

Drosophila microRNAs 263a/b Confer Robustness during Development by Protecting Nascent Sense Organs from Apoptosis

microRNA-263a/b confer robustness to sense organ development by controlling expression of the pro-apoptotic gene hid during apoptotic tissue pruning in Drosophila

Integration of Transcriptomics, Proteomics, and MicroRNA Analyses Reveals Novel MicroRNA Regulation of Targets in the Mammalian Inner Ear

We have employed a novel approach for the identification of functionally important microRNA (miRNA)-target interactions, integrating miRNA, transcriptome and proteome profiles and advanced in silico analysis using the FAME algorithm. Since miRNAs play a crucial role in the inner ear, demonstrated by the discovery of mutations in a miRNA leading to human and mouse deafness, we applied this approach to microdissected auditory and vestibular sensory epithelia. We detected the expression of 157 miRNAs in the inner ear sensory epithelia, with 53 miRNAs differentially expressed between the cochlea and vestibule. Functionally important miRNAs were determined by searching for enriched or depleted targets in the transcript and protein datasets with an expression consistent with the dogma of miRNA regulation. Importantly, quite a few of the targets were detected only in the protein datasets, attributable to regulation by translational suppression. We identified and experimentally validated the regulation of PSIP1-P75, a transcriptional co-activator previously unknown in the inner ear, by miR-135b, in vestibular hair cells. Our findings suggest that miR-135b serves as a cellular effector, involved in regulating some of the differences between the cochlear and vestibular hair cells