345 research outputs found
Performance of a C4F8O Gas Radiator Ring Imaging Cherenkov Detector Using Multi-anode Photomultiplier Tubes
We report on test results of a novel ring imaging Cherenkov (RICH) detection
system consisting of a 3 meter long gaseous C4F8O radiator, a focusing mirror,
and a photon detector array based on Hamamatsu multi-anode photomultiplier
tubes. This system was developed to identify charged particles in the momentum
range from 3-70 GeV/c for the BTeV experiment.Comment: 28 pages, 23 figures, submitted to Nuclear Instruments and Method
The Cleo Rich Detector
We describe the design, construction and performance of a Ring Imaging
Cherenkov Detector (RICH) constructed to identify charged particles in the CLEO
experiment. Cherenkov radiation occurs in LiF crystals, both planar and ones
with a novel ``sawtooth''-shaped exit surface. Photons in the wavelength
interval 135--165 nm are detected using multi-wire chambers filled with a
mixture of methane gas and triethylamine vapor. Excellent pion/kaon separation
is demonstrated.Comment: 75 pages, 57 figures, (updated July 26, 2005 to reflect reviewers
comments), to be published in NIM
Symmetries and observables in topological gravity
After a brief review of topological gravity, we present a superspace approach
to this theory. This formulation allows us to recover in a natural manner
various known results and to gain some insight into the precise relationship
between different approaches to topological gravity. Though the main focus of
our work is on the vielbein formalism, we also discuss the metric approach and
its relationship with the former formalism.Comment: 34 pages; a few explanations added in subsection 2.2.1, published
version of pape
Measurement of the eta-Meson Mass using psi(2S) --> eta J/psi
We measure the mass of the eta meson using psi(2S) --> eta J/psi events
acquired with the CLEO-c detector operating at the CESR e+e- collider. Using
the four decay modes eta --> gamma gamma, 3pi0, pi+pi-pi0, and pi+pi-gamma, we
find M(eta)=547.785 +- 0.017 +- 0.057 MeV, in which the first uncertainty is
statistical and the second systematic. This result has an uncertainty
comparable to the two most precise previous measurements and is consistent with
that of NA48, but is inconsistent at the level of 6.5sigma with the much
smaller mass obtained by GEM.Comment: 10 pages postscript,also available through
http://www.lns.cornell.edu/public/CLNS/2007/, Submitted to PR
Suppressed Decays of D_s^+ Mesons to Two Pseudoscalar Mesons
Using data collected near the Ds*+ Ds- peak production energy Ecm = 4170 MeV
by the CLEO-c detector, we study the decays of Ds+ mesons to two pseudoscalar
mesons. We report on searches for the singly-Cabibbo-suppressed Ds+ decay modes
K+ eta, K+ eta', pi+ K0S, K+ pi0, and the isospin-forbidden decay mode Ds+ to
pi+ pi0. We normalize with respect to the Cabibbo-favored Ds+ modes pi+ eta,
pi+ eta', and K+ K0S, and obtain ratios of branching fractions: Ds+ to K+ eta /
Ds+ to pi+ eta = (8.9 +- 1.5 +- 0.4)%, Ds+ to K+ eta' / Ds+ to pi+ eta' = (4.2
+- 1.3 +- 0.3)%, Ds+ to pi+ K0S / Ds+ to K+ K0S = (8.2 +- 0.9 +- 0.2)%, Ds+ to
K+ pi0 / Ds+ to K+ K0S = (5.0 +- 1.2 +- 0.6)%, and Ds+ to pi+ pi0 / Ds+ to K+
K0S < 4.1% at 90% CL, where the uncertainties are statistical and systematic,
respectively.Comment: 9 pages postscript,also available through
http://www.lns.cornell.edu/public/CLNS/2007/, Submitted to PR
Measurement of Absolute Hadronic Branching Fractions of D Mesons and e^+ e^- --> D D-bar Cross Sections at the psi(3770)
Using 281 /pb of e^+ e^- collisions recorded at the psi(3770) resonance with
the CLEO-c detector at CESR, we determine absolute hadronic branching fractions
of charged and neutral D mesons using a double tag technique. Among
measurements for three D^0 and six D^+ modes, we obtain reference branching
fractions B(D^0 --> K^-pi^+) = (3.891 +- 0.035 +- 0.059 +- 0.035)% and B(D^+
--> K^-pi^+pi^+) = (9.14 +- 0.10 +- 0.16 +- 0.07)%, where the first uncertainty
is statistical, the second is all systematic errors other than final state
radiation (FSR), and the third is the systematic uncertainty due to FSR. We
include FSR in these branching fractions by allowing for additional unobserved
photons in the final state. Using an independent determination of the
integrated luminosity, we also extract the cross sections sigma(e+e- --> D^0
D^0-bar) = (3.66+- 0.03 +- 0.06) nb and sigma(e+e- --> D^+ D^-) = (2.91+- 0.03
+- 0.05) nb at a center of mass energy, E_cm = 3774 +- 1 MeV.Comment: 47 pages, postscript also available through this
http://www.lns.cornell.edu/public/CLNS/2007/, to be published in PRD, updated
branching fractions using B(KS0 --> pi+ pi-) from PDG 2007, and updated text
in response to the PRD reviewe
A Study of Exclusive Charmless Semileptonic B Decays and Extraction of |V_{ub}| at CLEO
We have studied semileptonic B decay to the exclusive charmless states pi,
rho/omega, eta and eta' using the full 15.5 fb^-1 CLEO Upsilon(4S) sample, with
measurements performed in subregions of phase space to minimize dependence on a
priori knowledge of the form factors involved. We find total branching
fractions B(B^0 -> pi^-l^+nu) = (1.37 +- 0.15_stat +- 0.11_sys) x 10^-4 and
B(B^0 -> rho^- l^+ nu) = (2.93 +- 0.37_stat +- 0.37_sys) x 10^-4. We find
evidence for B^+ -> eta' l^+ nu, with B(B^+ -> eta' l^+ nu) = (2.66 +-
0.80_stat +- 0.56_sys) x 10^-4 and 1.20 x 10^-4 eta' l^+ nu) < 4.46
x 10^-4 (90% CL). We also limit B(B^+ -> eta l^+ nu) < 1.01 x 10^-4 (90% CL).
By combining our B -> pi l nu information with unquenched lattice calculations,
we find |V_ub| = (3.6 +- 0.4 +- 0.2 +0.6 -0.4) x 10^-3, where the errors are
statistical, experimental systematic, and theoretical systematic, respectively.Comment: 35 pages, 15 figures; revise
Assessment and Validation of Globodera pallida as a Novel In Vivo Model for Studying Alzheimer’s Disease
Publication history: Accepted - 11 September 2021; Published online - 19 September 2021.Background: Whole transgenic or non-transgenic organism model systems allow the screening of pharmacological compounds for protective actions in Alzheimer’s disease (AD). Aim: In this study, a plant parasitic nematode, Globodera pallida, which assimilates intact peptides from the external environment, was investigated as a new potential non-transgenic model system of AD. Methods: Fresh second-stage juveniles of G. pallida were used to measure their chemosensory, perform immunocytochemistry on their neurological structures, evaluate their survival rate, measure reactive oxygen species, and determine total oxidized glutathione to reduced glutathione ratio (GSSG/GSH) levels, before and after treatment with 100 µM of various amyloid beta (Aβ) peptides (1–40, 1–42, 17–42, 17–40, 1–28, or 1–16). Wild-type N2 C. elegans (strain N2) was cultured on Nematode Growth Medium and directly used, as control, for chemosensory assays. Results: We demonstrated that: (i) G. pallida (unlike Caenorhabditis elegans) assimilates amyloid-β (Aβ) peptides which co-localise with its neurological structures; (ii) pre-treatment with various Aβ isoforms (1–40, 1–42, 17–42, 17–40, 1–28, or 1–16) impairs G. pallida’s chemotaxis to differing extents; (iii) Aβ peptides reduced survival, increased the production of ROS, and increased GSSG/GSH levels in this model; (iv) this unique model can distinguish differences between different treatment concentrations, durations, and modalities, displaying good sensitivity; (v) clinically approved neuroprotective agents were effective in protecting G. pallida from Aβ (1–42) exposure. Taken together, the data indicate that G. pallida is an interesting in vivo model with strong potential for discovery of novel bioactive compounds with anti-AD activity.N.A.A. received a PhD studentship from Shaqra University, KSA and the Saudi Cultural Bureau in London (UKSACB). B.D.G.’s laboratory has received support for AD research from
Alzheimer’s Research UK (ARUK-NC2019-NI), the Medical Research Council (MRC) (CIC-CD1718-
CIC25), US-Ireland Health and Social Care NI (HSC R&DST/5460/2018) and InvestNI (RD101427
11-01-17-008). This work was also supported by Shaqra University, Saudi Arabi
Measurement of the Decay Constant using $D_S^+ --> ell^+ nu
We measure the decay constant fDs using the Ds -> l+ nu channel, where the l+
designates either a mu+ or a tau+, when the tau+ -> pi+ nu. Using both
measurements we find fDs = 274 +-13 +- 7 MeV. Combining with our previous
determination of fD+, we compute the ratio fDs/fD+ = 1.23 +- 0.11 +- 0.04. We
compare with theoretical estimates.Comment: 6 pages postscript,also available through
http://www.lns.cornell.edu/public/CLNS/2007
Measurement of Interfering K^*+K^- and K^*-K^+ Amplitudes in the Decay D^0 --> K^+K^-pi^0
We have studied the Cabibbo-suppressed decay mode D^0 into K^+ K^- pi^0 using
a Dalitz plot technique and find the strong phase difference delta_D [defined
as delta_(K*^- K^+) - delta_(K*^+ K^-)] = 332 degrees +- 8 degrees +- 11
degrees and relative amplitude r_D [defined as a_(K*^- K^+) / a_(K*^+ K^-)] =
0.52 +- 0.05 +- 0.04. This measurement indicates significant destructive
interference between D^0 into K^+ (K^- pi^0)_K*^- and D^0 into K^- (K^+
pi^0)_K*^+ in the Dalitz plot region where these two modes overlap. This
analysis uses 9.0 fb^(-1) of data collected at s^(1/2) of approximately 10.58
GeV with the CLEO III detector.Comment: 10 pages postscript,also available through
http://www.lns.cornell.edu/public/CLNS/2006/, Submitted to Phys. Rev. D
(Rapid Communications
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