2 research outputs found
Aminolysis of Aryl Ester Using Tertiary Amine as Amino Donor via C–O and C–N Bond Activations
An aminolysis reaction between various
aryl esters and inert tertiary
amines by C–O and C–N bond activations has been developed
for the selective synthesis of a broad scope of tertiary amides under
neutral and mild conditions. The mechanism may undergo the two key
steps of oxidative addition of acyl C–O bond in parent ester
and C–N bond cleavage of tertiary amine via an iminium-type
intermediate
Energy-Efficient Green Catalysis: Supported Gold Nanoparticle-Catalyzed Aminolysis of Esters with Inert Tertiary Amines by C–O and C–N Bond Activations
Catalyzed
by supported gold nanoparticles, an aminolysis reaction
between various aryl esters and inert tertiary amines by C–O
and C–N bond activations has been developed for the selective
synthesis of tertiary amides. Comparison studies indicated that the
gold nanoparticles could perform energy-efficient green catalysis
at room temperature, whereas PdÂ(OAc)<sub>2</sub> could not