Dietary and individual habits in women with breast cancer in Yazd Province

Cancer is the third leading cause of death in the world and is complex because of multifactor. More than 30 of cancer deaths could be prevented by changes on factors such as smoking, overweight, unhealthy foods, low fruit and vegetable intake, physical inactivity, and air pollution. Breast cancer is the most common cancer in Iranian women. Breast cancer burden is twofold in Yazd than Iran. This study was conducted with the aim of survey of the risk factors associated with breast cancer in Yazd hospitals. in this case-control study, 150 cases and 150 controls were examined. Factors of personal and feeding patient�s habits were studied. Sampling conducted with the way available. Data collection was conducted through interview. Analysis was done by SPSS using statistical tests x2 and logistic regression. mean and standard deviation age of cases and controls subjects was 51.61 10.52 and 51.55 10.27 respectively. Factors of education, exercise duration, exposure to smoke, sleep duration, consumption of dairy products, oil, fast food, fried food, meat, fruit and vegetables were a significant difference in the groups (p 0.05). note that in this study the dietary habits and physical activity were identified influencing factors suggesting people have to take care for the prevention and take care for the prevention and early detection. © 2015, International Journal of Pharmacy and Technology. All rights reserved

Exosomes and microRNAs: New potential therapeutic candidates in Alzheimer disease therapy

Exosomes are biological nanocarriers which could be involved in a variety of basic physiological events. They exert their effects via targeting their cargos (i.e., DNAs, messenger RNAs, microRNAs miRNAs, and proteins) to host cells, which led to change behaviors of recipient cells. One of the important aspects of exosomes is the roles of them in disease conditions. Increasing evidence indicated that exosomes are one of the main players in Alzheimer�s disease (AD) pathogenesis. Hence, it seems that these nanocarriers could be used as diagnostic and therapeutic biomarkers in AD treatment. Another important player in AD pathogenesis is miRNA. MiRNAs are short noncoding RNAs which exert their effects as epigenetic regulators. These molecules involved in different stages of AD. Therefore, miRNAs could be used as prognostic, diagnostic, and therapeutic biomarkers in AD. Here, we summarized various roles of exosomes and application of them in AD pathogenesis. Moreover, we highlighted the utilization of miRNAs as a therapeutic option in AD therapy. © 2018 Wiley Periodicals, Inc

Exosomes and microRNAs: New potential therapeutic candidates in Alzheimer disease therapy

Exosomes are biological nanocarriers which could be involved in a variety of basic physiological events. They exert their effects via targeting their cargos (i.e., DNAs, messenger RNAs, microRNAs miRNAs, and proteins) to host cells, which led to change behaviors of recipient cells. One of the important aspects of exosomes is the roles of them in disease conditions. Increasing evidence indicated that exosomes are one of the main players in Alzheimer�s disease (AD) pathogenesis. Hence, it seems that these nanocarriers could be used as diagnostic and therapeutic biomarkers in AD treatment. Another important player in AD pathogenesis is miRNA. MiRNAs are short noncoding RNAs which exert their effects as epigenetic regulators. These molecules involved in different stages of AD. Therefore, miRNAs could be used as prognostic, diagnostic, and therapeutic biomarkers in AD. Here, we summarized various roles of exosomes and application of them in AD pathogenesis. Moreover, we highlighted the utilization of miRNAs as a therapeutic option in AD therapy. © 2018 Wiley Periodicals, Inc

Modeling of Venus, Mars, and Titan

International audienceIncreased computer capacity has made it possible to model the global plasma and neutral dynamics near Venus, Mars and Saturn's moon Titan. The plasma interactions at Venus, Mars, and Titan are similar because each possess a substantial atmosphere but lacks a global internally generated magnetic field. In this article three self-consistent plasma models are described: the magnetohydrodynamic (MHD) model, the hybrid model and the fully kinetic plasma model. Chamberlain and Monte Carlo models of the Martian exosphere are also described. In particular, we describe the pros and cons of each model approach. Results from simulations are presented to demonstrate the ability of the models to capture the known plasma and neutral dynamics near the three objects