Effect of Pterygium Surgery on Tear Osmolarity

Purpose. To investigate changes of dry eye test results in patients who underwent pterygium surgery. Methods. Seventy-four patients who underwent primary pterygium surgery were enrolled in this study. At the baseline, 3-, 12-, and 18-month visits, measurements of tear osmolarity, BUT, and Schirmer test were performed. The patients were divided into 2 groups: Group 1, which consisted of patients in whom pterygium did not recur, and Group 2, which consisted of patients in whom pterygium recurred after surgery. Results. The patients in Group 1 had lower tear osmolarity levels after surgery than those at baseline (all P0.05). Conclusions. Anormal tear film function associated with pterygium. Pterygium excision improved tear osmolarity and tear film function. However, tear osmolarity deteriorated again with the recurrence of pterygium

Serum YKL-40 levels as a novel marker of inflammation and endothelial dysfunction in patients with pseudoexfoliation syndrome

WOS: 000321700800013PubMed: 23661157Purpose To evaluate serum levels of YKL-40 in patients with pseudoexfoliation syndrome (PEX) in comparison with those of age-and sex-matched healthy subjects. Methods Forty patients with PEX (PEX group) and 40 age- and sex-matched control subjects (control group) were enrolled in the study. An enzyme immunoassay method using the commercially available test MicroVue YKL-40 was used to measure serum YKL-40 concentration. Systolic and diastolic blood pressures, serum levels of high sensitivity C-reactive protein (hsCRP), total cholesterol, low-density lipoprotein cholesterol (LDL), high-density lipoprotein cholesterol (HDL), and triglycerides were also examined. Results the mean age was 54.4 +/- 7.6 (ranging 41-65) years in each group. the mean serum YKL-40 level of the PEX group was significantly higher than that of the control group (P<0.001). in addition, the mean serum HsCRP, total cholesterol, LDL, and triglycerides levels were significantly higher, and mean serum HDL level was significantly lower in the PEX group than in the control group (all P<0.001, excluding both P = 0.002 for triglycerides and HDL levels). Further, the mean systolic and diastolic blood pressures were significantly higher in the PEX group than in the control group (P-1 = 0.001 and P-2 = 0.01, respectively). Conclusion We have shown a relationship between PEX and elevated serum levels of YKL-40. We imply that a better understanding of the role of YKL-40 in the pathogenesis of endothelial dysfunction and atherosclerosis is necessary to develop new therapies for preventing or treating PEX. Further studies are warranted to clarify the clinical relevance of these findings

A Cause of Recurrent Urinary Retention in Pregnancy; Retroverted Uterus: Case Report

Acute urinary retention is one of the most common situations encountered in urological emergencies. It is more frequently seen in older men. Acuteurinary retention in pregnant women is a rare condition but it may cause abortus, preterm labor and rarely uterine ischemia. It is very difficult to revealthe causes of acute urinary retention in pregnant women. One of them is acute urinary retention due to retroverted uterus which is observed in 11% ofpregnant women. In this case, we discussed a young pregnant patient who presented to our outpatient clinic with complaints of recurrent urinary retentiondue to retroverted uterus.</p

Primer Mesane Lenfoması: Olgu Sunumu

Mesane karsinomu üriner sistemin en sıkgörülen tümörüdür. Malign mesane kanserlerinin % 90’dan fazlası, transizyonel hücrelitümörlerdir. Mesanenin transizyonel olmayantümörleri tüm mesane tümörlerinin %5-7’sinioluşturur. Bunların da yaklaşık %3’ü skuamöz hücreli karsinom, %2’si adenokarsinom,%1’i undiferansiye karsinom ve daha nadirenküçük hücreli karsinom ve lenfomadır. Mesanenin primer lenfoması çok nadir görülür.Nadir olmasına rağmen, bu tümörler ürologlartarafından akılda tutulmalı ve sıradışı mesanekitlelerinde düşünülmelidir. Bu yazıda mesanetümörü ön tanısı ile ameliyat edilen primermesane lenfoması olgusunu sunuyoruzBladder carcinoma is the most commontumor of the urinary system. More than 90% of malignant bladder cancers are transitional cell tumors. Non-transitional tumorsof the bladder account for 5-7 % of all bladder tumors; 3 % squamous cell carcinoma, 2% adenocarcinoma, 1 % indifferentiated carcinoma and, more rarely, small cell carcinomas and lymphoma. Primary lymphoma ofthe bladder is very rare. Although rare thesetumors should be kept in mind by urologistsand should be considered in unusual bladder masses. In this article, we present a caseof primary bladder lymphoma who was operated with a preliminary diagnosis of bladdertumor.</p

First-line treatment posterior tibial nerve stimulation in patients with interstitial cystitis/bladder pain syndrome

Introduction The aim of this study was to determine the effects of first-line treatment posterior tibial nerve stimulation (PTNS), applied once a week for a 12 week period, as a treatment modality for patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). Material and methods A total of 39 female patients with IC/BPS were enrolled in the study. Patients had one 30-minute session of PTNS per week for 12 weeks and symptoms were assessed before and after the treatment sessions by the use of a voiding diary, visual analog scale (VAS) for pain, O'LearySant interstitial cystitis symptom index (ICSI), and O'Leary-Sant interstitial cystitis problem index (ICPI). Results The mean age of the patients was 38.9 +/- 7.1 years. The improvements in voiding diary parameters after 12 weeks of PTNS treatment were statistically significant compared to baseline but the changes in nocturia, and average voiding volume were not statistically significant. Mean parametric improvements after 12 weeks of PTNS treatment compared to baseline included a daytime frequency decrease by 3.8 voids daily, urgency episodes decrease by 4.7 episodes daily, nocturia decrease by 0.3 voids and voided volume improvement by a mean of 8.4 ml. The difference for ICSI, ICPI and VAS between baseline and the 12th week of PTNS treatment scores demonstrated statistically significant improvements in pain severity, symptom and problem index. Conclusions The findings in this study demonstrated the improvements of voiding diaries, ICSI, ICPI and VAS scores in patients with IC/BPS after 12 weeks PTNS. PTNS treatment is a beneficial firs-line treatment option to IC/BPS symptom amelioration

Intravitreal triamcinolone acetonide versus pars plana vitrectomy for pseudophakic cystoid macular edema

WOS: 000311546500013PubMed: 22928501Purpose: To compare the efficacy of intravitreal triamcinolone acetonide injection versus 23-gauge pars plana vitrectomy with internal limiting membrane peeling for the treatment of chronic pseudophakic cystoid macular edema (CME) after uncomplicated cataract surgery. Methods: This retrospective, comparative, consecutive case series study included 39 patients with chronic pseudophakic CME. Twenty eyes in 20 patients were treated with intravitreal triamcinolone acetonide injection (IVT group), and 19 eyes in 19 patients were treated with pars plana vitrectomy with internal limiting membrane peeling (PPV group). in both groups, complete ophthalmologic examinations were performed before and after procedures. Findings were compared between the groups. Results: Both groups experienced a significant improvement in visual acuity and macular thickness after 12 months follow-up. At months 1 and 2, the IVT group showed a significant improvement in visual acuity and a significant reduction in macular thickness compared with the PPV group (p < 0.05), but these differences were not statistically significant between the groups after the 12-month period. Conclusion: Both intravitreal steroid injection and pars plana vitrectomy with internal limiting membrane peeling had a favorable effect on visual and anatomic results in patients with chronic pseudophakic CME. However, surgical treatment had no advantage over intravitreal triamcinolone acetonide injection after 12-months follow-up