23 research outputs found

    Beam and SKS spectrometers at the K1.8 beam line

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    High-resolution spectrometers for both incident beams and scattered particles have been constructed at the K1.8 beam line of the Hadron Experimental Facility at J-PARC. A point-to-point optics is realized between the entrance and exit of QQDQQ magnets for the beam spectrometer. Fine-pitch wire chamber trackers and hodoscope counters are installed in the beam spectrometer to accept a high rate beam up to 107 Hz. The superconducting kaon spectrometer for scattered particles was transferred from KEK with modifications to the cryogenic system and detectors. A missing-mass resolution of 1.9 ± 0.1 MeV/c2 (FWHM) was achieved for the ∑ peaks of (π±, K+) reactions on a proton target in the first physics run of E19 in 2010

    Heuristic model for configurable polymer wire synaptic devices

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    Recently, there has been considerable research on nonvolatile analog devices for artificial intelligence (AI); however, it focuses on all-coupled neural networks. In contrast, polymer wire-type synaptic devices, which can be expected to be arbitrarily wired similar to a biological neural network, have already been proposed and demonstrated. In this study, we model a polymer wire synaptic device based on the results of previous research, and demonstrate an example of applying simple perceptron (AI) to the model. The results of our study show that it is possible to predict effective methods of using polymer wire synaptic elements in AI

    Long- and Short-Term Conductance Control of Artificial Polymer Wire Synapses

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    Networks in the human brain are extremely complex and sophisticated. The abstract model of the human brain has been used in software development, specifically in artificial intelligence. Despite the remarkable outcomes achieved using artificial intelligence, the approach consumes a huge amount of computational resources. A possible solution to this issue is the development of processing circuits that physically resemble an artificial brain, which can offer low-energy loss and high-speed processing. This study demonstrated the synaptic functions of conductive polymer wires linking arbitrary electrodes in solution. By controlling the conductance of the wires, synaptic functions such as long-term potentiation and short-term plasticity were achieved, which are similar to the manner in which a synapse changes the strength of its connections. This novel organic artificial synapse can be used to construct information-processing circuits by wiring from scratch and learning efficiently in response to external stimuli

    Reaction mechanism of tetrathionate hydrolysis based on the crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans

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    Tetrathionate hydrolase (4THase) plays an important role in dissimilatory sulfur oxidation in the acidophilic iron- and sulfur-oxidizing bacterium Acidithiobacillus ferrooxidans. The structure of recombinant 4THase from A. ferrooxidans (Af-Tth) was determined by X-ray crystallography to a resolution of 1.95 Å. Af-Tth is a homodimer, and its monomer structure exhibits an eight-bladed β-propeller motif. Two insertion loops participate in dimerization, and one loop forms a cavity with the β-propeller region. We observed unexplained electron densities in this cavity of the substrate-soaked structure. The anomalous difference map generated using diffraction data collected at a wavelength of 1.9 Å indicated the presence of polymerized sulfur atoms. Asp325, a highly conserved residue among 4THases, was located near the polymerized sulfur atoms. 4THase activity was completely abolished in the site-specific Af-Tth D325N variant, suggesting that Asp325 plays a crucial role in the first step of tetrathionate hydrolysis. Considering that the Af-Tth reaction occurs only under acidic pH, Asp325 acts as an acid for the tetrathionate hydrolysis reaction. The polymerized sulfur atoms in the active site cavity may represent the intermediate product in the subsequent step

    The J-PARC heavy ion project

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    A project to study high-density nuclear matter using heavy ion collisions in a beam energy range of few GeV is being prepared at J-PARC. The goal of the project is to perform experiments with beam energies of 1-12 AGeV/c and the collision rate of 1011 Hz. The project is divided into two phases. For the first stage, measurements with a limited beam intensity will be performed with upgraded spectrometer of an on-going experiment. Full performance will be implemented at the second phase to study in detail the high density matter and light hypernuclei. Feasibility of measurements for both phases are being evaluated
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