Upaya Ukraina Menghadapi Rusia Atas Aneksasi Semenanjung Crimea Tahun 2014

This research aimed to describe the efforts of Ukraine after the annexation Crimea on Rusia. The problem appear since Ukraine President Viktor Yakunovych cancelled the associ-ation agreement with European Union (UE) that made citizens demonstrated to make Ya-kunovych descend. The new government had been rejected by Ukraine citizens and demon-strated to rejected the new government (pro UE).The perspective that applied in this reserch is realist, state level analysis, and also use theory security strategy. This theory talks about to securitization of their own state.Threats appear because the different perception or interest between interactions from two sides.Russia as super power state (economy and military) unbalance with Ukraine. There-fore, strategy Ukraine to protect their state by changing their foreign policy into Pro West (United States of America, European Union and North Atlantic Treaty Organization) to give sanctions for Russia, to protect Ukraine from influence of Russia, and to get acknowledge-ment that the referendum of Crimea was not validKeywords: Ukraine ,Russia, Annexation, Respons, Crimea, European Union, NAT

Canine and feline oral pathology

The aim of this work was to present a brief review of the main conditions affecting the oral cavity of dogs and cats. In recent years there has been increased attention with regard to veterinary dentistry, being several and frequent the pathologies located in the oral cavity of our pets. These diseases mainly affect the teeth and the mucous membranes of the oral cavity, and may, in chronic cases, also affect vital organs. This condition could have different causes, including hereditary, congenital, infectious, tumoural and even traumatic, requiring specific therapeutic approaches (Bellows, 2010; Holmstrom et al., 2007).FCT&DETS (PEest-OE/CED/UI4016/2011

Feline oral pathology

The main pathologies of the oral cavity are of utmost importance, not only by the number of exposed individuals, but also by the consequences which stems. With the development of this work, we intend to conduct a brief approach to the same, since, specifically affecting domestic felines. Feline Lymphoplasmatic Gingivostomatitis (GELF), the Feline Odontoclastic Reabsorption Lesions (LROF) Complex and gingivitis-stomatitis-pharyngitis, have been studied, some of which are considered an enigma in veterinary dentistry, this is because there are still many uncertainties about the true causes, which sometimes cause irreversible damage.FCT&DETS (PEest-OE/CED/UI4016/2011

The ELPAT Living Organ Donor Psychosocial Assessment Tool (EPAT): from 'What' to 'How' of Psychosocial Screening - a Pilot Study

Thorough psychosocial screening of donor candidates is required in order to minimize potential negative consequences and to strive for optimal safety within living donation programmes. We aimed to develop an evidence-based tool to standardize the psychosocial screening process. Key concepts of psychosocial screening were used to structure our tool: motivation and decision-making, personal resources, psychopathology, social resources, ethical and legal factors and information and risk processing. We (i) discussed how each item per concept could be measured, (ii) reviewed and rated available validated tools, (iii) where necessary developed new items, (iv) assessed content validity and (v) pilot-tested the new items. The resulting ELPAT living organ donor Psychosocial Assessment Tool (EPAT) consists of a selection of validated questionnaires (28 items in total), a semi-structured interview (43 questions) and a Red Flag Checklist. We outline optimal procedures and conditions for implementing this tool. The EPAT and user manual are available from the authors. Use of this tool will standardize the psychosocial screening procedure ensuring that no psychosocial issues are overlooked and ensure that comparable selection criteria are used and facilitate generation of comparable psychosocial data on living donor candidates.info:eu-repo/semantics/publishedVersio

Relação causal da vacinação e o fibrossarcoma vacinal felino

Os Fibrossarcomas dos felinos domésticos estão reconhecidos desde há 10 anos e têm vindo a alertar os Veterinários, os proprietários e os fabricantes de vacinas, devido à possível ligação do acto de vacinação ao desenvolvimento deste sarcoma. A partir da década de 90, registou-se o aumento dos casos deste tumor na região cervical e interescapular dos gatos, locais frequentemente utilizados para a inoculação de vacinas e outros fármacos injetáveis. Existem relatos da ocorrência de fibrossarcomas após a aplicação subcutânea e intramuscular da vacina trivalente, de antibióticos, corticosteroides, fluidoterapia subcutânea e desparasitantes anti-pulgas injetáveis

CIÊNCIAS AGRÁRIAS, ALIMENTARES E VETERINÁRIAS AGRICULTURAL SCIENCES, FOOD AND VETERINARY CIENCIAS AGRÍCOLAS, ALIMENTOS Y VETERINARIA millenium ADAPtAção Do moDElo ABCDE PArA ComunICAr A má notíCIA Ao ProPrIEtárIo Do PACIEntE ONCOLÓGICO EM MEDICINA VETERIN

Vala, H., Esteves, F., Mega, A., Santos, C., Cruz, R., 1 RESUMO Introdução: À semelhança do que ocorre na Medicina Humana, também em Medicina Veterinária, a prevalência da doença oncológica em animais de companhia tem vindo a aumentar significativamente. Desenvolvimento: A evolução da Medicina Veterinária, nas últimas décadas, veio trazer mudança nos paradigmas clínicos, nomeadamente no respeitante à relação com o animal mas também com o proprietário. Sendo a oncologia a especialidade em que há maior probabilidade de ter que comunicar uma má notícia, neste trabalho propõe-se a adaptação do modelo ABCDE da Medicina Humana para a Medicina Veterinária. Conclusões: A adaptação do modelo ABCDE para a Medicina Veterinária permite melhorar a comunicação com o proprietário cuidador e dotar os profissionais da equipe Médica Veterinária de melhores competências. Palavras-chave: animais de companhia; oncologia veterinária; comunicação; má notícia; modelo ABCDE

Stroke genetics: prospects for personalized medicine.

Epidemiologic evidence supports a genetic predisposition to stroke. Recent advances, primarily using the genome-wide association study approach, are transforming what we know about the genetics of multifactorial stroke, and are identifying novel stroke genes. The current findings are consistent with different stroke subtypes having different genetic architecture. These discoveries may identify novel pathways involved in stroke pathogenesis, and suggest new treatment approaches. However, the already identified genetic variants explain only a small proportion of overall stroke risk, and therefore are not currently useful in predicting risk for the individual patient. Such risk prediction may become a reality as identification of a greater number of stroke risk variants that explain the majority of genetic risk proceeds, and perhaps when information on rare variants, identified by whole-genome sequencing, is also incorporated into risk algorithms. Pharmacogenomics may offer the potential for earlier implementation of 'personalized genetic' medicine. Genetic variants affecting clopidogrel and warfarin metabolism may identify non-responders and reduce side-effects, but these approaches have not yet been widely adopted in clinical practice

Neuropsychiatric symptoms in 921 elderly subjects with dementia: a comparison between vascular and neurodegenerative types.

Objective:  i) to describe the neuropsychiatric profile of elderly subjects with dementia by comparing vascular (VaD) and degenerative dementias, i.e. dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD); ii) to assess whether the severity and type of dementia are associated with clinically relevant neuropsychiatric symptoms (CR‐NPS). Method:  One hundred and thirty‐one out‐patients with VaD, 100 with DLB and 690 with AD were studied. NPS were evaluated by the neuropsychiatric inventory (NPI). Results:  Vascular dementia had lower total and domain‐specific NPI scores and a lower frequency of CR‐NPS than AD and DLB, for which frequency of CR‐NPS increased significantly with disease severity, particularly in AD. Logistic regression analysis showed that a higher CDR score and a diagnosis of degenerative dementia were independently associated with CR‐NPS. Conclusion:  Vascular dementia is associated less with CR‐NPS than AD and DLB. Frequency of CR‐NPS increases with disease severity in AD and, to a lesser extent, in DLB

Antithrombotic Treatment in Transcatheter Aortic Valve Implantation Insights for Cerebrovascular and Bleeding Events

Transcatheter aortic valve implantation (TAVI) has emerged as a therapeutic alternative for patients with symptomatic aortic stenosis at high or prohibitive surgical risk. However, patients undergoing TAVI are also at high risk for both bleeding and stroke complications, and specific mechanical aspects of the procedure itself can increase the risk of these complications. The mechanisms of periprocedural bleeding complications seem to relate mainly to vascular/access site complications (related to the use of large catheters in a very old and frail elderly population), whereas the pathophysiology of cerebrovascular events remains largely unknown. Further, although mechanical complications, especially the interaction between the valve prosthesis and the native aortic valve, may play a major role in events that occur during TAVI, post-procedural events might also be related to a prothrombotic environment or state generated by the implanted valve, the occurrence of atrial arrhythmias, and associated comorbidities. Antithrombotic therapy in the setting of TAVI has been empirically determined, and unfractionated heparin during the procedure followed by dual antiplatelet therapy with aspirin (indefinitely) and clopidogrel (1 to 6 months) is the most commonly recommended treatment. However, bleeding and cerebrovascular events are common; these may be modifiable with optimization of periprocedural and post-procedural pharmacology. Further, as the field of antiplatelet and anticoagulant therapy evolves, potential drug combinations will multiply, introducing variability in treatment. Randomized trials are the best path forward to determine the balance between the efficacy and risks of antithrombotic treatment in this high risk-population