9 research outputs found
ΠΡΠ΅Π½ΠΊΠ° ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ ΠΊΠΈΡΡΠΈ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ ΠΎΡΡΡΡΡ Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ ΠΌΠΎΠ·Π³ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠΎΠ²ΠΎΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ
ΠΠΠΠΠ¦ΠΠΠ‘ΠΠΠ― Π ΠΠΠΠΠΠΠ’ΠΠ¦ΠΠ―ΠΠΠ‘Π’Π¬ Π Π£ΠΠΠΠΠ‘Π’Π¬ΠΠ‘ΠΠ₯ΠΠΠΠ’ΠΠ ΠΠΠ― ΠΠΠ’ΠΠΠΠΠ‘Π’Π¬ΠΠΠΠΠΠ’ΠΠΠ¬ΠΠ«Π₯ ΠΠΠΠ«ΠΠΠ Π ΠΠ‘Π‘Π’Π ΠΠΠ‘Π’ΠΠ /Π ΠΠΠΠΠΠ ΠΠΠΠΠΠΠ’ΠΠ¦ΠΠ― /ΠΠΠ’ΠΠΠ«ΠΠΠΠΠΠΠΠΠ ΠΠ ΠΠΠΠΠΠ ΠΠ©ΠΠΠΠ― Π ΠΠ‘Π‘Π’Π ΠΠΠ‘Π’ΠΠ /ΠΠ‘Π /Π ΠΠΠΠΠΠΠΠ§ΠΠΠΠΠ― ΠΠΠΠΠΠ‘Π’ΠΠΠΠΠΠΠΠΠ― ΠΠΠ’ΠΠ ΠΠΠΠ¦Π΅Π»ΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²Π»ΡΠ»ΠΎΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ, ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π½ΠΎΠ³ΠΎ Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ Π·Π΅ΡΠΊΠ°Π»ΡΠ½ΠΎΠΉ Π²ΠΈΠ·ΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΎΠ±ΡΠ°ΡΠ½ΠΎΠΉ ΡΠ²ΡΠ·ΠΈ, ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΈΠ½Π΄ΡΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ ΠΎΠ³ΡΠ°Π½ΠΈΡΠ΅Π½ΠΈΠ΅ΠΌ, ΠΌΠ΅ΡΠΎΠ΄Π° ΡΡΠ΅Π½ΠΈΡΠΎΠ²ΠΊΠΈ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΡΡ
Π½Π°Π²ΡΠΊΠΎΠ² ΠΊΠΈΡΡΠΈ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ Π»Π°ΡΠ΅ΠΊΡΠ½ΡΡ
ΡΠ΅Π·ΠΈΠ½ΠΎΠΊ ΠΈ Π°Π²ΡΠΎΡΡΠΊΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° ΡΡΠ΅Π½ΠΈΡΠΎΠ²ΠΊΠΈ ΠΌΠ΅Π»ΠΊΠΈΡ
ΠΌΠΎΡΠΎΡΠ½ΡΡ
Π½Π°Π²ΡΠΊΠΎΠ² Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ ΠΊΠΈΡΡΠΈ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ ΠΎΡΡΡΠΎΠ³ΠΎ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΠΌΠΎΠ·Π³ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠΎΠ²ΠΎΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ. Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΈΠ½ΡΠ»ΠΈ ΡΡΠ°ΡΡΠΈΠ΅ 62 ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°, ΡΠ°Π·Π΄Π΅Π»Π΅Π½Π½ΡΠ΅ Π½Π° 2 Π³ΡΡΠΏΠΏΡ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ, ΡΠΎΠΏΠΎΡΡΠ°Π²ΠΈΠΌΡΠ΅ ΠΏΠΎ ΠΏΠΎΠ»Ρ, Π²ΠΎΠ·ΡΠ°ΡΡΡ, ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΌΡ ΠΏΠ΅ΡΠΈΠΎΠ΄Ρ ΠΈ ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»Ρ. ΠΠ»Ρ Π°Π½Π°Π»ΠΈΠ·Π° ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π»ΠΈΡΡ ΠΌΠ΅ΡΠΎΠ΄Ρ ΠΎΡΠ΅Π½ΠΊΠΈ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² Ρ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ Π΄ΠΈΡΡΡΠ½ΠΊΡΠΈΠ΅ΠΉ ΠΊΠΈΡΡΠΈ, ΡΡΠ²Π΅ΡΠΆΠ΄Π΅Π½Π½ΡΠ΅ ΠΌΠΈΠ½ΠΈΡΡΠ΅ΡΡΡΠ²ΠΎΠΌ Π·Π΄ΡΠ°Π²ΠΎΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΡ Π Π΅ΡΠΏΡΠ±Π»ΠΈΠΊΠΈ ΠΠ΅Π»Π°ΡΡΡΡ. ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»ΠΎ Π²ΡΡΠ²Π»Π΅Π½ΠΎ ΠΌΠ΅ΠΆΠ³ΡΡΠΏΠΏΠΎΠ²ΠΎΠ΅ ΡΠ°Π·Π»ΠΈΡΠΈΠ΅ Π² Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΠΈ ΠΌΠ΅Π»ΠΊΠΎΠΉ ΠΌΠΎΡΠΎΡΠΈΠΊΠΈ, ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΊΠΈΡΡΠ΅Π²ΠΎΠΉ Π΄ΠΈΠ½Π°ΠΌΠΎΠΌΠ΅ΡΡΠΈΠΈ, ΡΡΠΎΠ²Π½Π΅ ΡΠ°ΠΌΠΎΠΎΡΠ΅Π½ΠΊΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΌ ΡΡΡΠ°ΡΡ ΡΡΠ½ΠΊΡΠΈΠΈ Π²Π΅ΡΡ
Π½Π΅ΠΉ ΠΊΠΎΠ½Π΅ΡΠ½ΠΎΡΡΠΈ, ΡΡΠ΅ΠΏΠ΅Π½ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΡΡΠ΅Π²ΠΎΠΆΠ½ΠΎΠΉ ΠΈ Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΠΌΠΏΡΠΎΠΌΠ°ΡΠΈΠΊΠΈ, ΠΏΡΠΎΡΠ²Π»ΡΡΡΠ΅Π΅ΡΡ Π² Π±ΠΎΠ»Π΅Π΅ ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΌ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π³ΡΡΠΏΠΏΡ. Π’Π°ΠΊΠΆΠ΅ Π²ΡΡΠ²Π»Π΅Π½ΠΎ ΠΏΡΠ΅ΠΎΠ±Π»Π°Π΄Π°Π½ΠΈΠ΅ ΡΠ²Π΅Π»ΠΈΡΠ΅Π½ΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»Π΅ΠΉ ΠΈ ΠΏΡΠΈ ΠΎΡΠ΅Π½ΠΊΠ΅ ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΆΠΈΠ·Π½ΠΈ Ρ ΡΠ΅ΡΠΏΠΎΠ½Π΄Π΅Π½ΡΠΎΠ², ΠΏΡΠΎΡ
ΠΎΠ΄ΡΡΠΈΡ
ΠΏΡΠ΅Π΄Π»ΠΎΠΆΠ΅Π½Π½ΡΠΉ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ Π½Π°Π΄ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ. Π Π°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π½ΡΠΉ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ, Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΏΡΠΈΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ Π°Π»Π³ΠΎΡΠΈΡΠΌΠΎΠΌ, ΠΏΠΎΠ·Π²ΠΎΠ»ΡΠ΅Ρ Π±ΠΎΠ»Π΅Π΅ ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎ ΠΏΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌΠΈ, ΠΏΡΠΎΡ
ΠΎΠ΄ΡΡΠΈΠΌΠΈ ΡΡΠ°Π½Π΄Π°ΡΡΠ½ΡΠΉ ΠΊΡΡΡ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΈ, Π²ΠΎΡΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ Π΄Π²ΠΈΠ³Π°ΡΠ΅Π»ΡΠ½ΡΠΉ Π½Π°Π²ΡΠΊ, ΡΡΡΠ°ΡΠ΅Π½Π½ΡΠΉ Π²ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΠ΅ ΠΎΡΡΡΠΎΠ³ΠΎ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΠΌΠΎΠ·Π³ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠΎΠ²ΠΎΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ, ΡΠ»ΡΡΡΠΈΡΡ ΡΡΠ΅ΠΏΠ΅Π½Ρ ΡΠ°ΠΌΠΎΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ, ΠΊΠ°ΡΠ΅ΡΡΠ²Π° ΠΆΠΈΠ·Π½ΠΈ ΠΈ ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΡΡΠ΅Π²ΠΎΠΆΠ½ΠΎ-Π΄Π΅ΠΏΡΠ΅ΡΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΠΌΠΏΡΠΎΠΌΠ°ΡΠΈΠΊΠΈ.Objectives. To study the efficacy of the medical rehabilitation complex developed on the basis of mirror visual feedback, elements of constraint induced movement therapy, the method of hand motor skillsβ training with the use of latex rubber bands and the authorβs own method of fine motor skills training in patients with motor dysfunction of the hand caused by acute cerebral circulation of different severity degree. Material and methods. The study involved 62 patients, divided into 2 comparison groups, matched by sex, age, rehabilitation period, and potential. To analyze the results we used methods for assessing the effectiveness of medical rehabilitation of patients with motor dysfunction of the hand, which were approved by the Ministry of Health of the Republic of Belarus. Results. The study revealed an intergroup difference in restoring fine motor skills, hand dynamometry indices, the patientβs self-assessment of the upper limb function loss, the severity of anxiety and depression symptoms, which manifests itself in a better result in patients of the clinical group. The prevalence of the increased indicators was also revealed when assessing the life quality of respondents undergoing the proposed complex of medical rehabilitation methods over patients of the control group. Conclusions. The developed complex, in terms of application in accordance with the algorithm, allows more qualitatively compared with patients undergoing a standard course of medical rehabilitation, to restore the motor skill lost because of acute cerebral circulation disturbance, to improve the degree of self-care, quality of life and leads to a decrease in anxiety-depression symptoms
Expression pattern of FCRL (FREB, FcRX) in normal and neoplastic human B cells.
FCRL (also known as FREB and FcRX) is a recently described member of the family of Fc receptors for immunoglobulin G (IgG). In the present study we analysed its expression in normal and neoplastic lymphoid tissue using immunohistochemical techniques. FCRL was preferentially expressed in a proportion of germinal centre cells and, more weakly, in mantle zone B cells. In addition, strong labelling was observed in marginal zone B cells in the spleen, representing one of the few markers for this cell type. The majority of cases of small B-cell lymphoma, diffuse large B-cell lymphoma and lymphocyte predominance Hodgkin's disease were positive for FCRL. However, the number of positive cells varied widely, and in consequence we could not define a cut-off that distinguished subsets of diffuse large B-cell lymphoma. Our results also showed that FCRL tended to be negative in T-cell-rich B-cell lymphoma and in classical Hodgkin's disease. FCRL may therefore represent a novel marker for normal B cells (e.g. splenic marginal zone cells) and may also be useful as a potential marker of B-cell neoplasms