24 research outputs found
The Persistence of Population III Star Formation
We present a semi-analytic model of star formation in the early universe,
beginning with the first metal-free stars. By employing a completely
feedback-limited star formation prescription, stars form at maximum efficiency
until the self-consistently calculated feedback processes halt formation. We
account for a number of feedback processes including a meta-galactic
Lyman-Werner background, supernovae, photoionization, and chemical feedback.
Halos are evolved combining mass accretion rates found through abundance
matching with our feedback-limited star formation prescription, allowing for a
variety of Population III (Pop III) initial mass functions (IMFs). We find
that, for a number of models, massive Pop III star formation can continue on
until at least and potentially past at rates of around
to M yr Mpc, assuming these stars
form in isolation. At this point Lyman-Werner feedback pushes the minimum halo
mass for star formation above the atomic cooling threshold, cutting off the
formation of massive Pop III stars. We find that, in most models, Pop II and
Pop III star formation co-exist over cosmological time-scales, with the total
star formation rate density and resulting radiation background strongly
dominated by the former before Pop III star formation finally ends. These halos
form at most M of massive Pop III stars during this phase
and typically have absolute magnitudes in the range of to . We also briefly discuss how future observations from telescopes such as
JWST or WFIRST and 21-cm experiments may be able to constrain unknown
parameters in our model such as the IMF, star formation prescription, or the
physics of massive Pop III stars.Comment: 16 pages, 13 figures, submitted to MNRA
The Effects of Population III X-ray and Radio Backgrounds on the Cosmological 21-cm Signal
We investigate the effects of Population III (Pop III) stars and their
remnants on the cosmological 21-cm global signal. By combining a semi-analytic
model of Pop III star formation with a global 21-cm simulation code, we
investigate how X-ray and radio emission from accreting Pop III black holes may
affect both the timing and depth of the 21-cm absorption feature that follows
the initial onset of star formation during the Cosmic Dawn. We compare our
results to the findings of the EDGES experiment, which has reported the first
detection of a cosmic 21-cm signal. In general, we find that our fiducial Pop
III models, which have peak star formation rate densities of
M yr Mpc between and , are able to
match the timing of the EDGES signal quite well, in contrast to models that
ignore Pop III stars. To match the unexpectedly large depth of the EDGES signal
without recourse to exotic physics, we vary the parameters of emission from
accreting black holes (formed as Pop III remnants) including the intrinsic
strength of X-ray and radio emission as well as the local column density of
neutral gas. We find that models with strong radio emission and relatively weak
X-ray emission can self-consistently match the EDGES signal, though this
solution requires fine-tuning. We are only able to produce signals with sharp
features similar to the EDGES signal if the Pop~III IMF is peaked narrowly
around .Comment: 11 pages, 8 figures, submitted to MNRA
A minimalist feedback-regulated model for galaxy formation during the epoch of reionization
Near-infrared surveys have now determined the luminosity functions of galaxies at 6 ≲ z ≲ 8 to impressive precision and identified a number of candidates at even earlier times. Here, we develop a simple analytic model to describe these populations that allows physically motivated extrapolation to earlier times and fainter luminosities. We assume that galaxies grow through accretion on to dark matter haloes, which we model by matching haloes at fixed number density across redshift, and that stellar feedback limits the star formation rate. We allow for a variety of feedback mechanisms, including regulation through supernova energy and momentum from radiation pressure. We show that reasonable choices for the feedback parameters can fit the available galaxy data, which in turn substantially limits the range of plausible extrapolations of the luminosity function to earlier times and fainter luminosities: for example, the global star formation rate declines rapidly (by a factor of ∼20 from z = 6 to 15 in our fiducial model), but the bright galaxies accessible to observations decline even faster (by a factor ≳ 400 over the same range). Our framework helps us develop intuition for the range of expectations permitted by simple models of high-z galaxies that build on our understanding of ‘normal’ galaxy evolution. We also provide predictions for galaxy measurements by future facilities, including James Webb Space Telescope and Wide-Field Infrared Survey Telescope
A minimalist feedback-regulated model for galaxy formation during the epoch of reionization
Near-infrared surveys have now determined the luminosity functions of galaxies at 6 ≲ z ≲ 8 to impressive precision and identified a number of candidates at even earlier times. Here, we develop a simple analytic model to describe these populations that allows physically motivated extrapolation to earlier times and fainter luminosities. We assume that galaxies grow through accretion on to dark matter haloes, which we model by matching haloes at fixed number density across redshift, and that stellar feedback limits the star formation rate. We allow for a variety of feedback mechanisms, including regulation through supernova energy and momentum from radiation pressure. We show that reasonable choices for the feedback parameters can fit the available galaxy data, which in turn substantially limits the range of plausible extrapolations of the luminosity function to earlier times and fainter luminosities: for example, the global star formation rate declines rapidly (by a factor of ∼20 from z = 6 to 15 in our fiducial model), but the bright galaxies accessible to observations decline even faster (by a factor ≳ 400 over the same range). Our framework helps us develop intuition for the range of expectations permitted by simple models of high-z galaxies that build on our understanding of ‘normal’ galaxy evolution. We also provide predictions for galaxy measurements by future facilities, including James Webb Space Telescope and Wide-Field Infrared Survey Telescope
Habitat Assessment of Non-Wadeable Rivers in Michigan
Habitat evaluation of wadeable streams based on accepted protocols provides a rapid and widely used adjunct to biological assessment. However, little effort has been devoted to habitat evaluation in non-wadeable rivers, where it is likely that protocols will differ and field logistics will be more challenging. We developed and tested a non-wadeable habitat index (NWHI) for rivers of Michigan, where non-wadeable rivers were defined as those of order ≥5, drainage area ≥1600 km 2 , mainstem lengths ≥100 km, and mean annual discharge ≥15 m 3 /s. This identified 22 candidate rivers that ranged in length from 103 to 825 km and in drainage area from 1620 to 16,860 km 2 . We measured 171 individual habitat variables over 2-km reaches at 35 locations on 14 rivers during 2000–2002, where mean wetted width was found to range from 32 to 185 m and mean thalweg depth from 0.8 to 8.3 m. We used correlation and principal components analysis to reduce the number of variables, and examined the spatial pattern of retained variables to exclude any that appeared to reflect spatial location rather than reach condition, resulting in 12 variables to be considered in the habitat index. The proposed NWHI included seven variables: riparian width, large woody debris, aquatic vegetation, bottom deposition, bank stability, thalweg substrate, and off-channel habitat. These variables were included because of their statistical association with independently derived measures of human disturbance in the riparian zone and the catchment, and because they are considered important in other habitat protocols or to the ecology of large rivers. Five variables were excluded because they were primarily related to river size rather than anthropogenic disturbance. This index correlated strongly with indices of disturbance based on the riparian (adjusted R 2 = 0.62) and the catchment (adjusted R 2 = 0.50), and distinguished the 35 river reaches into the categories of poor (2), fair (19), good (13), and excellent (1). Habitat variables retained in the NWHI differ from several used in wadeable streams, and place greater emphasis on known characteristic features of larger rivers.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/41269/1/267_2004_Article_141.pd
Ultra-rare genetic variation in common epilepsies: a case-control sequencing study
BACKGROUND:Despite progress in understanding the genetics of rare epilepsies, the more common epilepsies have proven less amenable to traditional gene-discovery analyses. We aimed to assess the contribution of ultra-rare genetic variation to common epilepsies. METHODS:We did a case-control sequencing study with exome sequence data from unrelated individuals clinically evaluated for one of the two most common epilepsy syndromes: familial genetic generalised epilepsy, or familial or sporadic non-acquired focal epilepsy. Individuals of any age were recruited between Nov 26, 2007, and Aug 2, 2013, through the multicentre Epilepsy Phenome/Genome Project and Epi4K collaborations, and samples were sequenced at the Institute for Genomic Medicine (New York, USA) between Feb 6, 2013, and Aug 18, 2015. To identify epilepsy risk signals, we tested all protein-coding genes for an excess of ultra-rare genetic variation among the cases, compared with control samples with no known epilepsy or epilepsy comorbidity sequenced through unrelated studies. FINDINGS:We separately compared the sequence data from 640 individuals with familial genetic generalised epilepsy and 525 individuals with familial non-acquired focal epilepsy to the same group of 3877 controls, and found significantly higher rates of ultra-rare deleterious variation in genes established as causative for dominant epilepsy disorders (familial genetic generalised epilepsy: odd ratio [OR] 2·3, 95% CI 1·7-3·2, p=9·1 × 10-8; familial non-acquired focal epilepsy 3·6, 2·7-4·9, p=1·1 × 10-17). Comparison of an additional cohort of 662 individuals with sporadic non-acquired focal epilepsy to controls did not identify study-wide significant signals. For the individuals with familial non-acquired focal epilepsy, we found that five known epilepsy genes ranked as the top five genes enriched for ultra-rare deleterious variation. After accounting for the control carrier rate, we estimate that these five genes contribute to the risk of epilepsy in approximately 8% of individuals with familial non-acquired focal epilepsy. Our analyses showed that no individual gene was significantly associated with familial genetic generalised epilepsy; however, known epilepsy genes had lower p values relative to the rest of the protein-coding genes (p=5·8 × 10-8) that were lower than expected from a random sampling of genes. INTERPRETATION:We identified excess ultra-rare variation in known epilepsy genes, which establishes a clear connection between the genetics of common and rare, severe epilepsies, and shows that the variants responsible for epilepsy risk are exceptionally rare in the general population. Our results suggest that the emerging paradigm of targeting of treatments to the genetic cause in rare devastating epilepsies might also extend to a proportion of common epilepsies. These findings might allow clinicians to broadly explain the cause of these syndromes to patients, and lay the foundation for possible precision treatments in the future. FUNDING:National Institute of Neurological Disorders and Stroke (NINDS), and Epilepsy Research UK
Recommended from our members
The effects of population III radiation backgrounds on the cosmological 21-cm signal
ABSTRACT
We investigate the effects of Population III (Pop III) stars and their remnants on the cosmological 21-cm global signal. By combining a semi-analytic model of Pop III star formation with a global 21-cm simulation code, we investigate how X-ray and radio emission from accreting Pop III black holes may affect both the timing and depth of the 21-cm absorption feature that follows the initial onset of star formation during the Cosmic Dawn. We compare our results to the findings of the EDGES experiment, which has reported the first detection of a cosmic 21-cm signal. In general, we find that our fiducial Pop III models, which have peak star formation rate densities of ∼10−4 M⊙ yr−1 Mpc−3 between z ∼ 10 and z ∼ 15, are able to match the timing of the EDGES signal quite well, in contrast to models that ignore Pop III stars. To match the unexpectedly large depth of the EDGES signal without recourse to exotic physics, we vary the parameters of emission from accreting black holes (formed as Pop III remnants) including the intrinsic strength of X-ray and radio emission as well as the local column density of neutral gas. We find that models with strong radio emission and relatively weak X-ray emission can self-consistently match the EDGES signal, though this solution requires fine-tuning. We are only able to produce signals with sharp features similar to the EDGES signal if the Pop III IMF is peaked narrowly around