3,773 research outputs found

    Predictability of catastrophic events: material rupture, earthquakes, turbulence, financial crashes and human birth

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    We propose that catastrophic events are "outliers" with statistically different properties than the rest of the population and result from mechanisms involving amplifying critical cascades. Applications and the potential for prediction are discussed in relation to the rupture of composite materials, great earthquakes, turbulence and abrupt changes of weather regimes, financial crashes and human parturition (birth).Comment: Latex document of 22 pages including 6 ps figures, in press in PNA

    Ultrasonic locating devices for central venous cannulation: meta-analysis

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    OBJECTIVES: To assess the evidence for the clinical effectiveness of ultrasound guided central venous cannulation. DATA SOURCES: 15 electronic bibliographic databases, covering biomedical, science, social science, health economics, and grey literature. DESIGN: Systematic review and meta-analysis of randomised controlled trials. POPULATIONS: Patients scheduled for central venous access. INTERVENTION REVIEWED: Guidance using real time two dimensional ultrasonography or Doppler needles and probes compared with the anatomical landmark method of cannulation. DATA EXTRACTION: Risk of failed catheter placement (primary outcome), risk of complications from placement, risk of failure on first attempt at placement, number of attempts to successful catheterisation, and time (seconds) to successful catheterisation. DATA SYNTHESIS: 18 trials (1646 participants) were identified. Compared with the landmark method, real time two dimensional ultrasound guidance for cannulating the internal jugular vein in adults was associated with a significantly lower failure rate both overall (relative risk 0.14, 95% confidence interval 0.06 to 0.33) and on the first attempt (0.59, 0.39 to 0.88). Limited evidence favoured two dimensional ultrasound guidance for subclavian vein and femoral vein procedures in adults (0.14, 0.04 to 0.57 and 0.29, 0.07 to 1.21, respectively). Three studies in infants confirmed a higher success rate with two dimensional ultrasonography for internal jugular procedures (0.15, 0.03 to 0.64). Doppler guided cannulation of the internal jugular vein in adults was more successful than the landmark method (0.39, 0.17 to 0.92), but the landmark method was more successful for subclavian vein procedures (1.48, 1.03 to 2.14). No significant difference was found between these techniques for cannulation of the internal jugular vein in infants. An indirect comparison of relative risks suggested that two dimensional ultrasonography would be more successful than Doppler guidance for subclavian vein procedures in adults (0.09, 0.02 to 0.38). CONCLUSIONS: Evidence supports the use of two dimensional ultrasonography for central venous cannulation

    Using Life History and Ecology as Tools to Manage a Threatened Salamander Species

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    Selected aspects of the life history and ecology of the small-mouthed salamander (Ambystoma texanum Matthes) relevant to the management of this threatened species in Iowa are presented. The population studied utilizes flooded woodland habitat during courtship, breeding and egg laying, and during the entire larval period. Larval foraging strategies in this habitat included ontogenetic but no diel shifts in prey selection. Synchronous, nocturnal breeding migration allowed effective use of drift fences fur capture of adults used in captive breeding, courtship behavior studies, and the estimation of breeding population size. Large numbers of spennatophores, apparently indiscriminate mate choice, and the relatively large number of eggs produced by females makes captive breeding programs potentially very successful. Because larvae are particularly vulnerable to predation by fish and larval tiger salamanders, ephemeral ponds are required for breeding and larval habitat. The primary management objective should be to preserve ephemeral woodland ponds and adjacent terrestrial habitat favorable for larval and adult survival

    Mild acetabular dysplasia and risk of osteoarthritis of the hip : a case-control study

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    Objective To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip. Methods The unaffected contralateral hip of patients with unilateral hip OA was compared with hips of asymptomatic controls without hip OA, derived from the Nottingham Genetics Osteoarthritis and Lifestyle case–control study. Standardised anteroposterior x-rays of the pelvis were used to measure centre edge (CE) angle and AD. Cut-off points for narrow CE angle and shallow AD were calculated from the control group (mean −1.96×SD). The relative risk of hip OA associated with each feature was estimated using OR and 95% CI and adjusted risks were calculated by logistic regression. Results In controls, both the CE angle and the AD were lower in the left hip than in the right hip. The CE angle related to age in both hips, and AD of the right hip was lower in men than in women. The contralateral unaffected hip in patients with unilateral hip OA had a decreased CE angle and AD compared with controls, irrespective of side. The lowest tertile of the CE angle in contralateral hips was associated with an eightfold risk of OA (aOR 8.06, 95% CI 4.87 to 13.35) and the lowest tertile of AD was associated with a 2.5-fold risk of OA (aOR 2.53, 95% CI 1.28 to 5.00). Significant increases in the risk of OA were also found as the CE angle and AD decreased
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