3,685 research outputs found
Modified bubble level senses pitch and roll angles over wide range
Bubble level sensor with fiber-optic field flattener is simple, rugged, small, and impervious to temperature and vibration effects. Pitch angles from -15 deg to +40 deg and roll angles of +30 deg are determined within 0.5 deg
Comparative genome analysis identifies few traits unique to the Escherichia coli ST131 H30Rx clade and extensive mosaicism at the capsule locus
Background: E.coli ST131 is a globally disseminated clone of multi-drug resistant E. coli responsible for that vast majority of global extra-intestinal E. coli infections. Recent global genomic epidemiological studies have highlighted the highly clonal nature of this group of bacteria, however there appears to be inconsistency in some phenotypes associated with the clone, in particular capsule types as determined by K-antigen testing both biochemically and by PCR. Results: We performed improved quality assemblies on ten ST131 genomes previously sequenced by our group and compared them to a new reference genome sequence JJ1886 to identify the capsule loci across the drug-resistant clone H30Rx. Our data shows considerable genetic diversity within the capsule locus of H30Rx clone strains which is mirrored by classical K antigen testing. The varying capsule locus types appear to be randomly distributed across the H30Rx phylogeny suggesting multiple recombination events at this locus, but that this capsule heterogeneity has little to no effect on virulence associated phenotypes in vitro. Conclusions: Our data provides a framework for determining the capsular genetics of E. coli ST131 and further beyond to ExPEC strains, and highlights how capsular mosaicism may be an important strategy in becoming a successful globally disseminated human pathogen
McGill University and Quebec City in the 1960s
In Canada and throughout the Western world, the 1960s was a tumultuous decade of student unrest and social/political upheaval. For Quebec, the 1960s was also the decade of la Revolution tranquille/Quiet Revolution, when francophone society’s self-definition underwent fundamental change. For McGill University, the decade’s changing environment required enormous adaptation: maintaining and extending academic programs and standards, restructuring governance and administration, expanding the physical plant, accommodating growing enrolment, seeking adequate funding, and adjusting to Quebec’s changing reality. A wide range of primary and secondary sources is available in recounting the story of McGill’s role in Quebec during the 1960s.ResuméAu Canada ainsi que partout ailleurs dans le monde occidental, les années 1960 furent une décénnie d’agitation étudiante et de perturbations sociales et politiques. Au Québec, les années 1960 furent aussi la décénnie de la Révolution tranquille, durant laquelle la manière dont la société francophone se définissait elle-même a subi un changement fondamental. Dans le cas de l’Université McGill, les transformations de l’environnement durant cette période ont nécessité énormément d’adaptation: le maintien et l’expansion des programmes et des normes académiques, la restructuration de la gouvernance et de l’administration, l’agrandissement des installations, l’accomodation du nombre croissant d’inscriptions, les efforts déployés pour assurer un financement adéquat, et l’ajustement de l’Université aux changements vécus par le Québec. Un large éventail de documentation primaire et secondaire est disponible pour relater l’histoire du rôle de McGill au Québec durant les années 1960
Gender-Neutral Language in Christian Universities
Award for Best Conference Paper2018 Northwest Undergraduate Conference in the HumanitiesThis paper provides brief summation of the methods transphobia are embodied through language and what the logical, moral, and business implications would be for a Christian University. In this paper, Adi McNally (who uses they/them pronouns) explores whether there is both scientific and theological weight behind transphobic and gendered language choices. They connect the Sapir-Whorf hypothesis of linguistic relativity to discussions around epicene pronouns and English grammatical development. Their argument explores writings from Doctors Lawrence Mayer and Paul McHugh, and its impact on traditionally conservative Christian thought. Further, they discuss alternative Christian viewpoints and how the core tenets of the Christian argue the necessity of gender-neutral and gender-conscious language.Faculty Sponsor: D. Berton Emerso
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