6,517 research outputs found
The surface science of quasicrystals
The surfaces of quasicrystals have been extensively studied since about 1990. In this paper we review work on the structure and morphology of clean surfaces, and their electronic and phonon structure. We also describe progress in adsorption and epitaxy studies. The paper is illustrated throughout with examples from the literature. We offer some reflections on the wider impact of this body of work and anticipate areas for future development.
(Some figures in this article are in colour only in the electronic version
Neurological effects in the offspring after switching from tobacco cigarettes to e-cigarettes during pregnancy in a mouse model.
BACKGROUND:Maternal smoking is currently a public health concern and has been associated with a number of complications in the offspring. E-cigarettes are gaining popularity as a 'safer' alternative to tobacco cigarettes during pregnancy, however, there are a limited number of studies to suggest that it is actually 'safe'. STUDY DESIGN:Balb/C female mice were exposed to ambient air (n = 8; Sham), or tobacco cigarette smoke (n = 8; SE) before gestation, during gestation and lactation. A third group was exposed to cigarette smoke before gestation followed by e-cigarette aerosols during gestation and lactation (n = 8; Switch). Male offspring (12-week old, n = 10-14/group) underwent behavioural assessments to investigate short-term memory, anxiety and activity using the novel object recognition (NOR) and elevated plus maze (EPM) tests. Brains were collected at postnatal day (P)1, P20 and Week13 for global DNA methylation, epigenetic gene expression, and neuronal cell counts. RESULTS:The offspring from mothers switching to e-cigarettes exhibited no change in exploration/activity, but showed a decrease in global DNA methylation, Aurora Kinase (Aurk) A and AurkB gene expression and a reduction in neuronal cell numbers in the cornu ammonis 1 region of the dorsal hippocampus compared to the SE group. CONCLUSIONS:Continuous tobacco cigarette smoke exposure during pregnancy resulted in marked neurological deficits in the offspring. Switching to e-cigarettes during pregnancy reduced these neurological deficits compared to cigarette smoke exposure. However, neurological changes were still observed, so we therefore conclude that e-cigarette use during pregnancy is not advised
The uptake of selenium by perennial ryegrass in soils of different organic matter contents receiving sheep excreta
Background and Aims
The intake of selenium, an essential element for animals and humans, in ruminants is largely determined by selenium concentration in ingested forages, which take up selenium mainly from soil. Ruminant excreta is a common source of organic fertilizer, which provides both nutrients and organic matter. This study aims to unentangle the unclear effect of applying different types of ruminant excreta in soils of different organic matter contents on selenium uptake by forage.
Methods
Perennial ryegrass (Lolium perenne) was grown in soils of different organic matter contents. Urine and/or feces collected from sheep fed with organic or inorganic mineral supplements, including selenium, were applied to the soils. The selenium in the collected samples were analyzed using ICP-MS. The associated biogeochemical reactions were scrutinized by wet chemistry.
Results
The application of urine and/or feces resulted in either the same or lower selenium concentrations in perennial ryegrass. The excreta type did not affect total selenium accumulation in grass grown in low organic matter soil, whereas in high organic matter soil, feces resulted in significantly lower total selenium accumulation than urine, which was attributed to a possible interaction of selenium sorption in soil and microbial reduction of Se.
Conclusion
This one-time excreta application did not increase, but further decrease in some treatments, selenium concentration and accumulation in the perennial ryegrass. Consequently, to increase ruminant selenium intake, supplementing selenium directly to animals is more recommended than applying animal manure to soil, which might drive selenium reduction and decrease selenium uptake by grass
Pseudomorphic Growth of a Single Element Quasiperiodic Ultrathin Film on a Quasicrystal Substrate
An ultrathin film with a periodic interlayer spacing was grown by the deposition of Cu atoms on thefivefold surface of the icosahedral Al70 Pd21 Mn9 quasicrystal. For coverages from 5 to 25 monolayers, a distinctive quasiperiodic low-energy electron diffraction pattern is observed. Scanning tunneling microscopy images show that the in-plane structure comprises rows having separations of S = 4.5 �0.2 �A and L = 7.3 0.3 A, whose ratio equals � =1.618... within experimental error. The sequences of such row separations form segments of terms of the Fibonacci sequence, indicative of the formation of a pseudomorphic Cu film
Magellanic Cloud X-ray Sources: III. Completion of a ROSAT Survey
This paper concludes a series of three papers presenting ROSAT
High-Resolution Imager (HRI) observations of unidentified Einstein and
serendipitous ROSAT X-ray sources in the direction of the Magellanic Clouds.
Accurate positions and fluxes have been measured for these sources. Optical
photometry and spectroscopy were obtained to search for identifications in
order to determine the physical nature of these sources. The present paper
includes new data for 24 objects; identifications are given or confirmed for 30
sources. For six sources optical finding charts showing the X-ray positions are
provided. The results from this program are summarized, showing the populations
of luminous X-ray sources in the Magellanic Clouds are quite different from
those in the Galaxy.Comment: 28 pages, 2 figures; to appear in Astronomical Journa
Key features of palliative care service delivery to Indigenous peoples in Australia, New Zealand, Canada and the United States: A comprehensive review
Background: Indigenous peoples in developed countries have reduced life expectancies, particularly from chronic diseases. The lack of access to and take up of palliative care services of Indigenous peoples is an ongoing concern.
Objectives: To examine and learn from published studies on provision of culturally safe palliative care service delivery to Indigenous people in Australia, New Zealand (NZ), Canada and the United States of America (USA); and to compare Indigenous peoples’ preferences, needs, opportunities and barriers to palliative care.
Methods: A comprehensive search of multiple databases was undertaken. Articles were included if they were published in English from 2000 onwards and related to palliative care service delivery for Indigenous populations; papers could use quantitative or qualitative approaches. Common themes were identified using thematic synthesis. Studies were evaluated using Daly’s hierarchy of evidence-for-practice in qualitative research.
Results: Of 522 articles screened, 39 were eligible for inclusion. Despite diversity in Indigenous peoples’ experiences across countries, some commonalities were noted in the preferences for palliative care of Indigenous people: to die close to or at home; involvement of family; and the integration of cultural practices. Barriers identified included inaccessibility, affordability, lack of awareness of services, perceptions of palliative care, and inappropriate services. Identified models attempted to address these gaps by adopting the following strategies: community engagement and ownership; flexibility in approach; continuing education and training; a whole-of-service approach; and local partnerships among multiple agencies. Better engagement with Indigenous clients, an increase in number of palliative care patients, improved outcomes, and understanding about palliative care by patients and their families were identified as positive achievements.
Conclusions: The results provide a comprehensive overview of identified effective practices with regards to palliative care delivered to Indigenous populations to guide future program developments in this field. Further research is required to explore the palliative care needs and experiences of Indigenous people living in urban areas
Correlating and Predicting the Air Infiltration Through the Cracks of Suspended Timber Floors
Developmentally vitamin D-deficient rats show enhanced prepulse inhibition after acute δ9-tetrahydrocannabinol
Developmental vitamin D (DVD) deficiency has been proposed as a risk factor for schizophrenia. DVD-deficient rats show selective cognitive deficits and novelty-induced hyperlocomotion and enhanced locomotor responses from acute treatment with psychomimetic drugs, such as amphetamine and MK-801. Here we aimed to examine the effect of a drug from a different class of psychomimetic/psychoactive compounds, Δ-tetrahydrocannabinol (THC), on tasks of relevance to the cognitive and positive symptoms of schizophrenia. The aim of this study was to investigate whether DVD deficiency modulates the behavioural effects of THC on tests of delay-dependent memory, sensorimotor gating and locomotion. Adult control and DVD-deficient rats were injected with THC (0, 0.3, 0.6, 1.25, 2.5 mg/kg) 15 min before a delay match to sample (DMTS) task using variable delays (0-24 s). A separate group of rats was injected with either 2.5 mg/kg THC or vehicle before tests of either prepulse inhibition (PPI) of the acoustic startle response or in the open field. Control and DVD-deficient rats showed a similar dose-dependent impairment in performance on the DMTS. The greatest impairment was observed at 2.5 mg/kg for all delays (0-24 s). DVD-deficient rats showed THC-induced enhancement of PPI, which was not observed in control rats. There was no effect of maternal diet on acoustic startle response or locomotor responses in the open field. This study reports the novel findings that DVD-deficient rats were more sensitive to the acute effects of THC on PPI. It appears that prenatal vitamin D deficiency has long-term effects on sensitivity to the behavioural effects of cannabinoids
Nitrogen Response of Spring and Winter Wheat to Biosolids Compared to Chemical Fertiliser
Irish sewage sludge production was over 30,000 t/year in the 1990s (EPA, Ireland, 2003). Application to agricultural land is a management option for this organic material as it results in the recycling of the nutrients they contain for crop production. The EU Directive (91/271/EEC) encourages the recycling of sewage sludge as biosolids to agriculture. However, up to 1999, only about 5 % of biosolids produced was applied to agricultural land. In this study, several biosolids and a chemical fertiliser were used to assess N availability for spring and winter wheat (Triticum aestivum,) production in a pot experiment
Genetic Synthesis of Periodic Protein Materials
Genetic engineering offers a novel approach to the development of
advanced polymeric materials, in particular protein-based materials.
Biological synthesis provides levels of control of polymer chain architecture
that cannot yet be attained by current methods of chemical synthesis. In
addition to employing naturally occurring genetic templates artificial genes
can be designed to encode completely new materials with customized properties.
In the present paper we: 1) review the concepts and technology of creating
protein-based materials by genetic engineering, 2) discuss the merits of
producing crystalline lamellar proteins by this approach, and 3) review
progress made by our group in generating such materials by genetic strategies.
Full descriptions appear elsewhere about the parameters to be considered in
designing artificial protein genes of this type, the effectiveness of
different gene construction and expression strategies utilized by us thus far
and, the specific properties of the various materials derived from these
efforts (1,2).
Progress made by other groups involved in developing periodic proteins by
molecular biological strategies are described in refs. 3-8. The latter
studies include genetic engineering of artificial silk-like proteins (3,4),
poly-aspartylphenylalanine (5), an α/β barrel domain (octarellin; 6), the
collagen tripeptide GlyProPro (7) and human tropoelastin (8). Advances with
the silk-like proteins (SLP) have been particularly impressive. In addition
to producing multi-gram quantities of pure SLP homopolymers, this group has successfully generated block copolymers of SLP interspersed with core peptides of mammalian elastin and the human fibronectin cell attachment element. While publications are still lacking it appears that a numiber of groups are striving to create genetically engineered variants of the repetitive bioadhesive proteins produced by mussels and barnacles (9)
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