New paradigms explore ‘systems-oriented’ ways of managing risk

Approaches based only on financial risk are blind to the multi-dimensional nature of the threats facing our world, write Katie Kedward, Martha McPherson and Ria Se

Unraveling the Impact of Dog-Friendly Spaces on Urban–Wildland Pumas and Other Wildlife

As the most widespread large carnivore on the planet, domestic dogs Canis lupus familiaris can pose a major threat to wildlife, even within protected areas (PAs). Growing human presence in PAs, coupled with increasing pet dog ownership underscores the urgency to understand the influence of dogs on wildlife activity and health. This knowledge can mitigate the adverse repercussions of recreation, optimizing PA management. Drawing on five years (2017–2021) of data from 101 camera traps in the San Francisco Bay Area, California, United States, we measured the spatiotemporal responses of puma Puma concolor, bobcat Lynx rufus, coyote Canis latrans, and mule deer Odocoileus hemionus towards domestic dogs. Additionally, using six years (2017–2022) of community science data, we explored the impacts of PA dog policies on puma sightings outside park boundaries. Puma responses provide insights into broader ecological impacts, while analyses of bobcat, coyote, and mule deer offer a comprehensive understanding of species responses to dog-friendly spaces. Because dogs can be perceived as predators or competitors by wildlife, we anticipated shifts in spatial and temporal activity patterns in response to dogs. Wildlife responses included avoidance (bobcat, puma) or spatial overlap (mule deer) for areas with more dogs, and no effect (coyote). Mule deer may benefit from a human shield provided by people with dogs, while pumas and bobcats appeared more sensitive, and coyotes more adaptable. Dog policies influenced puma and mule deer temporal activity, with increased nocturnal activity in dog-friendly PAs. Bobcat temporal activity was less variable in dog-friendly PAs and coyote activity was similar between treatments. Outside PAs, puma sightings increased with human disturbance. Our study underscores the trade-offs between recreation and wildlife conservation, emphasizing the need to quantify the ecological impacts of dogs. This understanding is vital for informing conservation strategies and promoting coexistence between dogs, wildlife, and protected environments

Understanding Music Interaction, and Why It Matters

This is the introductory chapter of a book dedicated to new research in, and emerging new understandings of, music and human-computer interaction—known for short as music interaction. Music interaction research plays a key role in innovative approaches to diverse musical activities, including performance, composition, education, analysis, production and collaborative music making. Music interaction is pivotal in new research directions in a range of activities, including audience participation, interaction between music and dancers, tools for algorithmic music, music video games, audio games, turntablism and live coding. More generally, music provides a powerful source of challenges and new ideas for human-computer interaction (HCI). This introductory chapter reviews the relationship between music and human-computer interaction and outlines research themes and issues that emerge from the collected work of researchers and practitioners in this book

Limitation of Life-Sustaining Care in the Critically Ill: A Systematic Review of the Literature

When life-sustaining treatments (LST) are no longer effective or consistent with patient preferences, limitations may be set so that LSTs are withdrawn or withheld from the patient. Many studies have examined the frequency of limitations of LST in intensive care unit (ICU) settings in the past 30 years. This systematic review describes variation and patient characteristics associated with limitations of LST in critically ill patients in all types of ICUs in the United States. A comprehensive search of the literature was performed by a medical librarian between December 2014 and April 2017. A total of 1,882 unique titles and abstracts were reviewed, 113 were selected for article review, and 36 studies were fully reviewed. Patient factors associated with an increased likelihood of limiting LST included white race, older age, female sex, poor preadmission functional status, multiple comorbidities, and worse illness severity score. Based on several large, multicenter studies, there was a trend toward a higher frequency of limitation of LST over time. However, there is large variability between ICUs in the proportion of patients with limitations and on the proportion of deaths preceded by a limitation. Increases in the frequency of limitations of LST over time suggests changing attitudes about aggressive end-of-life-care. Limitations are more common for patients with worse premorbid health and greater ICU illness severity. While some differences in the frequency of limitations of LST may be explained by personal factors such as race, there is unexplained wide variability between units

Smoking Related Home Oxygen Burn Injuries: Continued Cause for Alarm

Background: Home oxygen therapy is a mainstay of treatment for patients with various cardiopulmonary diseases. In spite of warnings against smoking while using home oxygen, many patients sustain burn injuries. Objectives: We aimed to quantify the morbidity and mortality of such patients admitted to our regional burn unit over a 6-year period. Methods: A retrospective chart review of all patients admitted to a regional burn center from 2008 through 2013 was completed. Admitted patients sustaining burns secondary to smoking while using home oxygen therapy were selected as the study population to determine morbidity. Results: Fifty-five subjects were admitted to the burn unit for smoking-related home oxygen injuries. The age range was 40-84 years. Almost all subjects were on home oxygen for chronic obstructive pulmonary disease (96%). Seventy-two percent of burns involved <5% of the total body surface area, 51% of patients were intubated, and of those 33% had evidence of inhalation injury. The hospital mortality rate was 14.5%. The mean length of hospital stay was 8.6 days, and 54.5% were discharged to a nursing home or another advanced facility. Finally, concomitant substance abuse was found in 27%, and a previous history of injury from smoking while on home oxygen was discovered in 14.5%. Conclusions: This single-center analysis is one of the largest describing burn injuries stemming from smoking while using home oxygen therapy. We identified the morbidity and mortality associated with these injuries. Ongoing education and careful consideration of prescribing home oxygen therapy for known smokers is highly encouraged

Antimicrobial catheters for reduction of symptomatic urinary tract infection in adults requiring short-term catheterisation in hospital : a multicentre randomised controlled trial

Copyright © 2012 Elsevier Ltd. All rights reserved. PMID: 23134837 [PubMed - indexed for MEDLINE]Peer reviewedPostprin

Financing for climate action

This policy brief summarises some of the recent research produced by thought leaders and researchers at UCL’s Institute for Innovation and Public Purpose (IIPP) exploring key questions around climate-aligned finance and sustainable growth. These include the pricing and financial risks related to the loss of nature and biodiversity; the importance of heterogeneous investors; scale economies and the commercialisation of innovative renewable energy technologies; and the role of central banks and public wealth funds in enabling a more rapid transition to a green economy

A systematic review of interventions to improve involvement in physical activity among adults with intellectual disability

Background: Evidence suggests that most adults with intellectual disability do not participate in sufficient amounts of physical activity (PA). A systematic review of peer-reviewed studies that reported an intervention aiming to improve PA levels of adults with intellectual disability was conducted. Methods: Keywords related to intellectual disability and physical activity were used to search relevant databases. Studies were excluded if they did not measure PA as an outcome for adults with intellectual disability, were non-English, and were not peer-reviewed. All relevant studies were included in the review regardless of methodological quality and design. Results: Six articles met the inclusion criteria. These included health education or health promotion programs with PA, nutrition, and weight loss components. The quality of studies included in this review was generally poor. Most studies used a prepost design, sample sizes were small, and measurement tools were used that are not valid and reliable for the population assessed. Conclusions: PA interventions have the potential to improve the health and wellbeing of people with intellectual disability, a vulnerable group who require attention from public health practitioners and researchers. Given the health inequities that exist, public health researchers should target efforts to improve PA levels among this group

The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation

Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear. The IL-17-producing Th17 subset of T cells has been widely implicated in MS and in the mouse model, experimental autoimmune encephalomyelitis (EAE). However, the differentiation and regulation of Th17 cells during EAE remain incompletely understood. Although evidence is mounting that the antimicrobial peptide cathelicidin profoundly affects early T cell differentiation, no studies have looked at its role in longer-term T cell responses. Now, we report that cathelicidin drives severe EAE disease. It is released from neutrophils, microglia, and endothelial cells throughout disease; its interaction with T cells potentiates Th17 differentiation in lymph nodes and Th17 to exTh17 plasticity and IFN-γ production in the spinal cord. As a consequence, mice lacking cathelicidin are protected from severe EAE. In addition, we show that cathelicidin is produced by the same cell types in the active brain lesions in human MS disease. We propose that cathelicidin exposure results in highly activated, cytokine-producing T cells, which drive autoimmunity; this is a mechanism through which neutrophils amplify inflammation in the central nervous system

Music and HCI

Music is an evolutionarily deep-rooted, abstract, real-time, complex, non-verbal, social activity. Consequently, interaction design in music can be a valuable source of challenges and new ideas for HCI. This workshop will reflect on the latest research in Music and HCI (Music Interaction for short), with the aim of strengthening the dialogue between the Music Interaction community and the wider HCI community. We will explore recent ideas from Music Interaction that may contribute new perspectives to general HCI practice, and conversely, recent HCI research in non-musical domains with implications for Music Interaction. We will also identify any concerns of Music Interaction that may require unique approaches. Contributors engaged in research in any area of Music Interaction or HCI who would like to contribute to a sustained widening of the dialogue between the distinctive concerns of the Music Interaction community and the wider HCI community will be welcome