LOCALIS: Locally-adaptive Line Simplification for GPU-based Geographic Vector Data Visualization

Visualization of large vector line data is a core task in geographic and cartographic systems. Vector maps are often displayed at different cartographic generalization levels, traditionally by using several discrete levels-of-detail (LODs). This limits the generalization levels to a fixed and predefined set of LODs, and generally does not support smooth LOD transitions. However, fast GPUs and novel line rendering techniques can be exploited to integrate dynamic vector map LOD management into GPU-based algorithms for locally-adaptive line simplification and real-time rendering. We propose a new technique that interactively visualizes large line vector datasets at variable LODs. It is based on the Douglas-Peucker line simplification principle, generating an exhaustive set of line segments whose specific subsets represent the lines at any variable LOD. At run time, an appropriate and view-dependent error metric supports screen-space adaptive LOD levels and the display of the correct subset of line segments accordingly. Our implementation shows that we can simplify and display large line datasets interactively. We can successfully apply line style patterns, dynamic LOD selection lenses, and anti-aliasing techniques to our line rendering

Body, brain, life for cognitive decline (BBL-CD): Protocol for a multidomain dementia risk reduction randomized controlled trial for subjective cognitive decline and mild cognitive impairment

This is the final version. Available from Dove Medical Press via the DOI in this record. Background: With no cure for dementia and the number of people living with the condition predicted to rapidly rise, there is an urgent need for dementia risk reduction and prevention interventions. Modifiable lifestyle risk factors have been identified as playing a major role in the development of dementia; hence, interventions addressing these risk factors represent a significant opportunity to reduce the number of people developing dementia. Relatively few interventions have been trialed in older participants with cognitive decline (secondary prevention). Objectives: This study evaluates the efficacy and feasibility of a multidomain lifestyle risk reduction intervention for people with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). Methods: This study is an 8-week, two-arm, single-blind, randomized controlled trial (RCT) of a lifestyle modification program to reduce dementia risk. The active control group receives the following four online educational modules: dementia literacy and lifestyle risk, Mediterranean diet (MeDi), cognitive engagement and physical activity. The intervention group also completes the same educational modules but receives additional practical components including sessions with a dietitian, online brain training and sessions with an exercise physiologist to assist with lifestyle modification. Results: Primary outcome measures are cognition (The Alzheimer’s Disease Assessment Scale-Cognitive-Plus [ADAS-Cog-Plus]) and a composite lifestyle risk factor score for Alzheimer’s disease (Australian National University – Alzheimer’s Disease Risk Index [ANU-ADRI]). Secondary outcome measures are motivation to change lifestyle (Motivation to Change Lifestyle and Health Behaviour for Dementia Risk Reduction [MCLHB-DRR]) and health-related quality of life (36-item Short Form Health Survey [SF-36]). Feasibility will be determined through adherence to diet (Mediterranean Diet Adherence Screener [MEDAS] and Australian Recommended Food Score [ARFS]), cognitive engagement (BrainHQ-derived statistics) and physical activity interventions (physical activity calendars). Outcomes are measured at baseline, immediately post-intervention and at 3-and 6-month follow-up by researchers blind to group allocation. Discussion: If successful and feasible, secondary prevention lifestyle interventions could provide a targeted, cost-effective way to reduce the number of people with cognitive decline going on to develop Alzheimer’s disease (AD) and other dementias.Dementia Australia Research FoundationAustralian National UniversityDementia Collaborative Research CentreNHMRC Centre for Research Excellence in Cognitive Health, the Australian National UniversityNeuroscience Research Australia, University of New South WalesRoyal Commonwealth Societ

CELLULAR REQUIREMENTS FOR THE PRIMARY IN VITRO ANTIBODY RESPONSE TO DNP-FICOLL

The cellular requirements for the primary in vitro IgM and IgG response to dinitrophenyl-substituted Ficoll were examined. Neither thymus-derived lymphocytes nor macrophage-rich splenic adherent cells were required for anti-DNP antibody synthesis. DNP-Ficoll is therefore tentatively classified as a "thymic-independent" antigen

(U-th)/he ages from the fuorite mineralization of the Tanguá Alkaline intrusion

The Tanguá Alkaline Suite formed as a result of Mesozoic to Cenozoic magmatic events that affected the part of the South American Platform in Brazil’s southeast. The alkaline intrusion is composed of alkali-feldspar syenite with nepheline (pulaskites and umptekites), syenite (with or without the presence of pseudo-leucite), varied nepheline syenites (foyaites, micro-foyaites etc.) and alkaline magmatic breccias. The intrusion contains important fluorite mineralization, in the form of NE-SW oriented veins, which were economically extracted in recent decades at the Emitang Mine. This paper focuses on the analysis of these centimetric crystals of fluorite which vary in color from (yellow, to white and pur-ple.) associated with mineralization of Tanguá Body. Geochronological dating by (U-Th)/He of fluorite mineralization showed a wide range of ages, with the oldest age of 74 ± 3 Ma (Late Cretaceous) and the youngest of 0.11 ± 0.02 Ma (Late Pleistocene). Most ages are concentrated between 25 and 8 Ma (Miocene). The oldest age (74.0 ± 3 Ma) is associated with hydrothermal fluids percolating at the time of intrusion of the Tanguá Body. The other ages represent episodes of percolation of hydrothermal fluids and consequent growth of fluorite crystals. Of note is a set of Miocene ages that can be associated with regional tectonic events. This phase of flurite growth may be associated with the reactivation of basement faults and structures in the Tanguá region and the circulation of hydrothermal fluids associated with intrusion of younger dikes. The youngest ages may be associated with neotectonic reactivation of faults during neotectonic events

Development of a generic activities model of command and control

This paper reports on five different models of command and control. Four different models are reviewed: a process model, a contextual control model, a decision ladder model and a functional model. Further to this, command and control activities are analysed in three distinct domains: armed forces, emergency services and civilian services. From this analysis, taxonomies of command and control activities are developed that give rise to an activities model of command and control. This model will be used to guide further research into technological support of command and control activities