828 research outputs found

    Professional decision making and women offenders : containing the chaos?

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    This article draws on the findings from research undertaken in south-east Scotland in 2008 which sought to identify the characteristics of female offenders and to document the views of policy makers and practitioners regarding the experiences of women involved in the Scottish criminal justice system. Despite Scotland having retained a stronger 'welfare' focus than elsewhere in the UK (e.g. McAra, 2008), this is not reflected in the treatment of women who offend, with the rate of female imprisonment having almost doubled in the last ten years and community based disposals falling short of a welfare-oriented system. This article explores why the treatment that women offenders receive in the criminal justice system may be harsh and disproportionate both in relation to their offending and in relation to the treatment of men. It is argued that interventions with women need to be initiated earlier in their cycle of offending and at an earlier stage in the criminal justice process but also that the wide-ranging health, welfare, financial and behavioural needs of women who offend cannot be met solely within an increasingly risk-averse and punitive criminal justice environment

    Communication risk and strategy in temporary organizations

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    Communication is a critical and emerging metric for successful outcomes in the high-stakes field of project management. Professional management societies have quantified financial losses caused by ineffective communication. Consulting project management exemplifies a maximum communication risk environment - misunderstanding threatens project finances, strict deadlines, and technical benchmarks - exacerbated by the complexity of a temporary organization structure. The context of work in a temporary organization adds layers of ambiguity to project communications - an ill-structured domain in technical communication terms. Formal study of communication in temporary organizations is relatively new. Recent studies are derived from engineering and business management perspectives. This baseline study investigates risk and strategy in temporary organizations from a communication perspective. Project management consultants dialogue about their experiences of project risk and communication strategy in a critical incident interview. This research identifies the communication complexities of work in these temporary contexts. Contrasting the base communication models of professional project management, this study proposes rhetorical analysis as a systems thinking strategy for project communication. This thesis argues that professional technical communication is strategic expertise and advocates humanistic strategies to mitigate the elevated sociotechnical communication risk within a temporary organization

    Employing dynamic fuzzy membership functions to assess environmental performance in the supplier selection process

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    The proposed system illustrates that logic fuzzy can be used to aid management in assessing a supplier's environmental performance in the supplier selection process. A user-centred hierarchical system employing scalable fuzzy membership functions implement human priorities in the supplier selection process, with particular focus on a supplier's environmental performance. Traditionally, when evaluating supplier performance, companies have considered criteria such as price, quality, flexibility, etc. These criteria are of varying importance to individual companies pertaining to their own specific objectives. However, with environmental pressures increasing, many companies have begun to give more attention to environmental issues and, in particular, to their suppliers’ environmental performance. The framework presented here was developed to introduce efficiently environmental criteria into the existing supplier selection process and to reflect on its relevant importance to individual companies. The system presented attempts to simulate the human preference given to particular supplier selection criteria with particular focus on environmental issues when considering supplier selection. The system considers environmental data from multiple aspects of a suppliers business, and based on the relevant impact this will have on a Buying Organization, a decision is reached on the suitability of the supplier. This enables a particular supplier's strengths and weaknesses to be considered as well as considering their significance and relevance to the Buying OrganizationPeer reviewe

    An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells.

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    Duchenne muscular dystrophy is a progressive and incurable neuromuscular disease caused by genetic and biochemical defects of the dystrophin-glycoprotein complex. Here we show the regenerative potential of myogenic progenitors derived from corrected dystrophic induced pluripotent stem cells generated from fibroblasts of mice lacking both dystrophin and utrophin. We correct the phenotype of dystrophic induced pluripotent stem cells using a Sleeping Beauty transposon system carrying the micro-utrophin gene, differentiate these cells into skeletal muscle progenitors and transplant them back into dystrophic mice. Engrafted muscles displayed large numbers of micro-utrophin-positive myofibers, with biochemically restored dystrophin-glycoprotein complex and improved contractile strength. The transplanted cells seed the satellite cell compartment, responded properly to injury and exhibit neuromuscular synapses. We also detect muscle engraftment after systemic delivery of these corrected progenitors. These results represent an important advance towards the future treatment of muscular dystrophies using genetically corrected autologous induced pluripotent stem cells
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