1,934 research outputs found
Low-speed aerodynamic characteristics of a 13-percent-thick airfoil section designed for general aviation applications
Wind-tunnel tests were conducted to determine the low-speed section characteristics of a 13 percent-thick airfoil designed for general aviation applications. The results were compared with NACA 12 percent-thick sections and with the 17 percent-thick NASA airfoil. The tests were conducted ovar a Mach number range from 0.10 to 0.35. Chord Reynolds numbers varied from about 2,000,000 to 9,000,000
The initiation and development of combustion under cold idling conditions using a glow plug in diesel engines
Factors determining the success or failure of combustion initiation using a glow plug have been investigated through experimental work on a single cylinder, common rail diesel engine with a geometric compression ratio of 15.5, and a quiescent combustion bomb with optical access. A glow plug was required to avoid engine misfires when bulk gas temperature at the start of injection was less than 413 C. The distance between the glow plug and the spray edge, the glow plug temperature, and the bulk gas temperature were important factors in meeting two requirements for successful ignition: a minimum local temperature of 413 C and a minimum air/fuel vapour equivalence ratio of 0.15â0.35
Characterization of the C. elegans erlin homologue
<p>Abstract</p> <p>Background</p> <p>Erlins are highly conserved proteins associated with lipid rafts within the endoplasmic reticulum (ER). Biochemical studies in mammalian cell lines have shown that erlins are required for ER associated protein degradation (ERAD) of activated inositol-1,4,5-trisphosphate receptors (IP3Rs), implying that erlin proteins might negatively regulate IP3R signalling. In humans, loss of erlin function appears to cause progressive intellectual disability, motor dysfunction and joint contractures. However, it is unknown if defects in IP3R ERAD are the underlying cause of this disease phenotype, whether ERAD of activated IP3Rs is the only function of erlin proteins, and what role ERAD plays in regulating IP3R-dependent processes in the context of an intact animal or embryo. In this study, we characterize the erlin homologue of the nematode <it>Caenorhabditis elegans </it>and examine erlin function <it>in vivo</it>. We specifically set out to test whether <it>C. elegans </it>erlin modulates IP3R-dependent processes, such as egg laying, embryonic development and defecation rates. We also explore the possibility that erlin might play a more general role in the ERAD pathway of <it>C. elegans</it>.</p> <p>Results</p> <p>We first show that the <it>C. elegans </it>erlin homologue, ERL-1, is highly similar to mammalian erlins with respect to amino acid sequence, domain structure, biochemical properties and subcellular location. ERL-1 is present throughout the <it>C. elegans </it>embryo; in adult worms, ERL-1 appears restricted to the germline. The expression pattern of ERL-1 thus only partially overlaps with that of ITR-1, eliminating the possibility of ERL-1 being a ubiquitous and necessary regulator of ITR-1. We show that loss of ERL-1 does not affect overall phenotype, or alter brood size, embryonic development or defecation cycle length in either wild type or sensitized <it>itr-1 </it>mutant animals. Moreover we show that ERL-1 deficient worms respond normally to ER stress conditions, suggesting that ERL-1 is not an essential component of the general ERAD pathway.</p> <p>Conclusions</p> <p>Although loss of erlin function apparently causes a strong phenotype in humans, no such effect is seen in <it>C. elegans</it>. <it>C. elegans </it>erlin does not appear to be a ubiquitous major modulator of IP3 receptor activity nor does erlin appear to play a major role in ERAD.</p
Recent modifications and calibration of the Langley low-turbulence pressure tunnel
Modifications to the Langley Low-Turbulence Pressure Tunnel are presented and a calibration of the mean flow parameters in the test section is provided. Also included are the operational capability of the tunnel and typical test results for both single-element and multi-element airfoils. Modifications to the facility consisted of the following: replacement of the original cooling coils and antiturbulence screens and addition of a tunnel-shell heating system, a two dimensional model-support and force-balance system, a sidewall boundary layer control system, a remote-controlled survey apparatus, and a new data acquisition system. A calibration of the mean flow parameters in the test section was conducted over the complete operational range of the tunnel. The calibration included dynamic-pressure measurements, Mach number distributions, flow-angularity measurements, boundary-layer characteristics, and total-pressure profiles. In addition, test-section turbulence measurements made after the tunnel modifications have been included with these calibration data to show a comparison of existing turbulence levels with data obtained for the facility in 1941 with the original screen installation
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Analysis and correction of noise on electronic circuits in an accelerator environment
Accelerator noise sources can cause both analog and digital electronic circuits to malfunction. This paper identifies and analyzes noise sources, and describes the methodology for measurement. Both general remedies and specific solutions to minimize the noise effects on accelerator electronic circuits are described. A policy for electronic design, board layout, assembly, and fabrication is established. Conclusions are drawn based on theoretical principles with practical examples shown in case studies
âEthnic groupâ, the state and the politics of representation
The assertion, even if only by implication, that âethnic groupâ categories represent ârealâ tangible entities, indeed identities, is commonplace not only in the realms of political and policy discourse but also amongst contemporary social scientists. This paper, following Brubaker (2002), questions this position in a number of key respects: of these three issues will dominate the discussion that follows.
First, there is an interrogation of the proposition that those to whom the categories/labels refer constitute sociologically meaningful âgroupsâ as distinct from (mere) human collectivities. Secondly, there is the question of how these categories emerge, i.e. exactly what series of events, negotiations and contestations lie behind their construction and social acceptance. Thirdly, and as a corollary to the latter point, we explore the process of reification that leads to these categories being seen to represent âreal things in the worldâ (ibid.)
Wind-tunnel tests of two airfoils for wind turbines operating at high Reynolds numbers
The objectives of this study were to verify the predictions of the Eppler Airfoil Design and Analysis Code for Reynolds numbers up to 6 x 106 and to acquire the section characteristics of two airfoils being considered for large, megawatt-size wind turbines. One airfoil, the S825, was designed to achieve a high maximum lift coefficient suitable for variable-speed machines. The other airfoil, the S827, was designed to achieve a low maximum lift coefficient suitable for stall-regulated machines. Both airfoils were tested in the NASA Langley Low-Turbulence Pressure Tunnel (LTPT) for smooth, fixed-transition, and rough surface conditions at Reynolds numbers of 1, 2, 3, 4, and 6 x 106. The results show the maximum lift coefficient of both airfoils is substantially underpredicted for Reynolds numbers over 3 x 106 and emphasized the difficulty of designing low-lift airfoils for high Reynolds numbers
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