Does the mode of delivery affect mathematics examination results?

At present most examinations are delivered on paper but there is a growing trend in many subjects to deliver some or part of these examinations by computer. It is therefore important to know whether there are any differences in the results obtained by candidates sitting examinations taken by computer compared with those obtained by candidates sitting conventional examinations using pen and paper. The purpose of this article is to describe the outcome of a pilot study designed to∗ investigate possible causes of any differences in results from the use of different modes of delivery in a mathematics examination. One outcome of this study was that the process of translating examination questions into a format required for use on the computer (but keeping this as a pen and paper test) can have a significant effect on examination results. However, the main conclusion is that changing the medium only has no effect on the results in mathematics examinations

Cytokine gene polymorphisms in preterm infants with necrotising enterocolitis: genetic association study

BACKGROUND The inflammatory cytokine cascade is implicated in the pathogenesis of necrotising enterocolitis (NEC). Genetic association studies of cytokine polymorphisms may help to detect molecular mechanisms that are causally related to the disease process. AIM To examine associations between the common genetic variants in candidate inflammatory cytokine genes and NEC in preterm infants. METHODS Multi-centre case-control and genetic association study. DNA samples were collected from 50 preterm infants with NEC and 50 controls matched for gestational age and ethnic group recruited to a multi-centre case-control study. Ten candidate single-nucleotide polymorphisms in cytokines previously associated with infectious or inflammatory diseases were genotyped. The findings were included in random-effects meta-analyses with data from previous genetic association studies. RESULTS All allele distributions were in Hardy-Weinberg equilibrium. None of the studied cytokine polymorphisms was significantly associated with NEC. Four previous genetic association studies of cytokine polymorphisms and NEC in preterm infants were found. Meta-analyses were possible for several single-nucleotide polymorphisms. These increased the precision of the estimates of effect size but did not reveal any significant associations. CONCLUSIONS The available data are not consistent with more than modest associations between these candidate cytokine variant alleles and NEC in preterm infants. Data from future association studies of these polymorphisms may be added to the meta-analyses to obtain more precise estimates of effects sizes.The study was funded by Tenovus (Scotland)

Evaluation of large area crop estimation techniques using LANDSAT and ground-derived data

The results of the Domestic Crops and Land Cover Classification and Clustering study on large area crop estimation using LANDSAT and ground truth data are reported. The current crop area estimation approach of the Economics and Statistics Service of the U.S. Department of Agriculture was evaluated in terms of the factors that are likely to influence the bias and variance of the estimator. Also, alternative procedures involving replacements for the clustering algorithm, the classifier, or the regression model used in the original U.S. Department of Agriculture procedures were investigated

Fast drift kilometric radio bursts and solar proton events

Initial results of a comparative study of major fast drift kilometric bursts and solar proton events from Sep. 1978 to Feb. 1983 are presented. It was found that only about half of all intense, long duration ( 40 min above 500 sfu) 1 MHz bursts can be associated with F 20 MeV proton events. However, for the subset of such fast drift bursts accompanied by metric Type 2 and/or 4 activity (approximately 40% of the total), the degree of association with 20 MeV events is 80%. For the reverse association, it was found that proton events with J( 20 MeV) 0.01 1 pr cm(-2)s(-1)sr(-1)MeV(-1) were typically (approximately 80% of the time) preceded by intense 1 MHz bursts that exceeded the 500 sfu level for times 20 min (median duration approximately 35 min)

Neuropsychological evaluation of blast-related concussion: Illustrating the challenges and complexities through OEF/OIF case studies

Background/objective: Soldiers of Operations Enduring Freedom (OEF) and Iraqi Freedom (OIF) sustain blast-related mild traumatic brain injury (concussion) with alarming regularity. This study discusses factors in addition to concussion, such as co-morbid psychological difficulty (e.g. post-traumatic stress) and symptom validity concerns that may complicate neuropsychological evaluation in the late stage of concussive injury. Case report: The study presents the complexities that accompany neuropsychological evaluation of blast concussion through discussion of three case reports of OEF/OIF personnel. Discussion: The authors emphasize uniform assessment of blast concussion, the importance of determining concussion severity according to acute-injury characteristics and elaborate upon non-concussion-related factors that may impact course of cognitive limitation. The authors conclude with a discussion of the need for future research examining the impact of blast concussion (particularly recurrent concussion) and neuropsychological performance

Evaluation Context Impacts Neuropsychological Performance of OEF/OIF Veterans with Reported Combat-Related Concussion

Although soldiers of Operations Iraqi Freedom (OIF) and Enduring Freedom (OEF) encounter combat-related concussion at an unprecedented rate, relatively few studies have examined how evaluation context, insufficient effort, and concussion history impact neuropsychological performances in the years following injury. The current study explores these issues in a sample of 119 U.S. veterans (OEF/OIF forensic concussion, n = 24; non-OEF/OIF forensic concussion, n = 20; OEF/OIF research concussion, n = 38; OEF/OIF research without concussion, n = 37). The OEF/OIF forensic concussion group exhibited significantly higher rates of insufficient effort relative to the OEF/OIF research concussion group, but a comparable rate of insufficient effort relative to the non-OEF/OIF forensic concussion group. After controlling for effort, the research concussion and the research non-concussion groups demonstrated comparable neuropsychological performance. Results highlight the importance of effort assessment among OEF/OIF and other veterans with concussion history, particularly in forensic contexts

A Primer on the Economics of Prescription Pharmaceutical Pricing in Health Insurance Markets

The pricing of medical products and services in the U.S. is notoriously complex. In health care, supply prices (those received by the manufacturer) are distinct from demand prices (those paid by the patient) due to health insurance. The insurer, in designing the benefit, decides what prices patients pay out-of-pocket for drugs and other products. In this primer we characterize cost and supply conditions in markets for generic and branded drugs, and apply basic tools of microeconomics to describe how an insurer, acting on behalf of its enrollees, would set demand prices for drugs. Importantly, we show how the market structure on the supply side, characterized alternatively by monopoly (unique brands), Bertrand differentiated product markets (therapeutic competition), and competition (generics), influences the insurer’s choices about demand prices. This perspective sheds light on the choice of coinsurance versus copayments, the structure of tiered formularies, and developments in the retail market.

Static and Dynamic Magnetism in Underdoped Superconductor BaFe1.92_{1.92}Co0.08_{0.08}As2_2

We report neutron scattering measurements on single crystals of BaFe$_{1.92}$Co$_{0.08}$As$_2$. The magnetic Bragg peak intensity is reduced by 6 % upon cooling through T$_C$. The spin dynamics exhibit a gap of 8 meV with anisotropic three-dimensional (3d) interactions. Below T$_C$ additional intensity appears at an energy of $\sim$4.5(0.5) meV similar to previous observations of a spin resonance in other Fe-based superconductors. No further gapping of the spin excitations is observed below T$_C$ for energies down to 2 meV. These observations suggest the redistribution of spectral weight from the magnetic Bragg position to a spin resonance demonstrating the direct competition between static magnetic order and superconductivity.Comment: 4 pages, 4 figure

Dephasing Effects by Ferromagnetic Boundary on Resistivity in Disordered Metallic Layer

The resistivity of disordered metallic layer sandwiched by two ferromagnetic layers at low-temperature is investigated theoretically. It is shown that the magnetic field acting at the interface does not affect the classical Boltzmann resistivity but causes a dephasing among electrons in the presence of the spin-orbit interaction, suppressing the anti-localization due to the spin-orbit interaction. The dephasing turns out to be stronger in the case where the magnetization of the two layers is parallel, contributing to a positive magnetoresistance close to a switching field at low temperature.Comment: 11 pages, 3 figures. Title modified in journal versio