MS

thesisAn attempt was made to isolate secretory component from the molecule secretory Immunoglobulin A. Two methods were used, each with colostrum as the source of secretory component. In the first method, colostrum was centrifuged, and the supernatant was chromatographed on a Sephadex G-200 column. Half of the eluates were concentrated by negative pressure dialysis, and half of the eluates were chromatographed on a carboxymethyl-50 cation exchange column. All eluates collected were subjected to Immunoelectrophoresis. In the second method the colostrum was clarified, and the proteins were precipitated by the addition of ammonium sulfate. The eluates were chromatographed on a DEAE cellulose column using a stepwise elution of three sodium phosphate buffers. Further chromatography included a GM-50 cation exchange column and identification of the proteins by the method of Ouchterlony using rabbit antiserum against secretory IgA. Free or unattached secretory component was found in the second elution peaks from the Sephadex G-200 gel filtration column and from the first fraction of colostral whey eluted using O.OIM sodium phosphate buffer, at pH 7.6. Secretory component was highly contaminated with lactoferrln and was not obtained In a pure state. Failure to obtain spurring between second peak eluates and antl S-IgA could be the result of differences in quarternary structure between the tetramerlc free form and the IgA bound form

A História da Alimentação: balizas historiográficas

Os M. pretenderam traçar um quadro da História da Alimentação, não como um novo ramo epistemológico da disciplina, mas como um campo em desenvolvimento de práticas e atividades especializadas, incluindo pesquisa, formação, publicações, associações, encontros acadêmicos, etc. Um breve relato das condições em que tal campo se assentou faz-se preceder de um panorama dos estudos de alimentação e temas correia tos, em geral, segundo cinco abardagens Ia biológica, a econômica, a social, a cultural e a filosófica!, assim como da identificação das contribuições mais relevantes da Antropologia, Arqueologia, Sociologia e Geografia. A fim de comentar a multiforme e volumosa bibliografia histórica, foi ela organizada segundo critérios morfológicos. A seguir, alguns tópicos importantes mereceram tratamento à parte: a fome, o alimento e o domínio religioso, as descobertas européias e a difusão mundial de alimentos, gosto e gastronomia. O artigo se encerra com um rápido balanço crítico da historiografia brasileira sobre o tema

Buku Ajar Patofisiologi Edisi Ke-6 Volume 1

xiv, 544 hlm.; 28 x 21 c

Buku Ajar Patofisiologi Edisi Ke-6 Volume 2

xiv, 526 hlm.; 28 x 21 c

Understanding Pathophysiology - ANZ adaptation [1st edition.]

Pathophysiology is a complex, though essential, component of all undergraduate nursing courses and there is an identified need for a text tailored specifically for the Australian and New Zealand student. The entrenched bio-medical terminology can often be difficult to relate to nursing practice. To overcome this, the authors have presented pathophysiology in an accessible manner appropriate to undergraduate students, providing a balance between science, clinical case material and pharmacology. This adaptation prioritises the diseases relevant to nursing students and presents them according to their prevalence and rate of incidence in Australia and New Zealand. This focused approach prepares students for the presentations they will experience in a clinical setting. Each body system is explored first by structure and function, then by alteration.This establishes the physiology prior to addressing the diseases relative to the system and allows the student to analyse and compare the normal versus altered state. A lifespan approach is incorporated in the Alterations chapters, as each chapter addresses childhood diseases through to the aged with respect to each body system. A new section on Contemporary Health Issues examines the effects of an aging population and lifestyle choices on the overall health of our society. These are explored through specific chapters on Stress; Genes and the Environment; Obesity and Diabetes; Cancer; Mental Illness and Indigenous health issues. Concept maps are used to assist students to understand the basic concepts of each chapter and are used as a foundation for more complex discussions. Clinical case studies are also included in each chapter to bring pathophysiology into practice. Each patient case study will highlight relevant symptoms of a given disease within a clinical setting. This is analysed with respect to the relevancy of each given symptom, their respective affect on body systems and the best course of pharmacological treatment. This forthcoming textbook is an adaptation of Understanding Pathophysiology 4e by Huether & McCance. It builds on the strengths of the US edition while tailoring it to the specific needs of Australia and New Zealand undergraduate nursing students. As such it is an invaluable text which will compliment your suite of Elsevier nursing titles