2,996 research outputs found
The Effect of the Short-Range Correlations on the Generalized Momentum Distribution in Finite Nuclei
The effect of dynamical short-range correlations on the generalized momentum
distribution in the case of , -closed shell
nuclei is investigated by introducing Jastrow-type correlations in the
harmonic-oscillator model. First, a low order approximation is considered and
applied to the nucleus He. Compact analytical expressions are derived and
numerical results are presented and the effect of center-of-mass corrections is
estimated. Next, an approximation is proposed for of
heavier nuclei, that uses the above correlated of He.
Results are presented for the nucleus O. It is found that the effect of
short-range correlations is significant for rather large values of the momenta
and/or and should be included, along with center of mass corrections
for light nuclei, in a reliable evaluation of in the whole
domain of and .Comment: 29 pages, 8 figures. Further results, figures and discussion for the
CM corrections are added. Accepted by Journal of Physics
High-momentum dynamic structure function of liquid 3He-4He mixtures: a microscopic approach
The high-momentum dynamic structure function of liquid 3He-4He mixtures has
been studied introducing final state effects. Corrections to the impulse
approximation have been included using a generalized Gersch-Rodriguez theory
that properly takes into account the Fermi statistics of 3He atoms. The
microscopic inputs, as the momentum distributions and the two-body density
matrices, correspond to a variational (fermi)-hypernetted chain calculation.
The agreement with experimental data obtained at \AA is not
completely satisfactory, the comparison being difficult due to inconsistencies
present in the scattering measurements. The significant differences between the
experimental determinations of the 4He condensate fraction and the 3He kinetic
energy, and the theoretical results, still remain unsolved.Comment: 18 pages, 11 figures, to appear in Phys. Rev.
Azimuthal Correlation in Lepton-Hadron Scattering via Charged Weak-Current Processes
We consider the azimuthal correlation of the final-state particles in charged
weak-current processes. This correlation provides a test of perturbative
quantum chromodynamics. The azimuthal asymmetry is large in the semi-inclusive
processes in which we identify a final-state hadron, say, a charged pion
compared to that in the inclusive processes in which we do not identify
final-state particles and use only the calorimetric information. In
semi-inclusive processes the azimuthal asymmetry is more conspicuous when the
incident lepton is an antineutrino or a positron than when the incident lepton
is a neutrino or an electron. We analyze all the possible charged weak-current
processes and study the quantitative aspects of each process. We also compare
this result to the ep scattering with a photon exchange.Comment: 25 pages, 2 Postscript figures, uses RevTeX, fixes.st
The Genetic resistence to Coccidia in Appenninica sheep
The study was conducted on a single herd of Appenninica sheep breed situated in Tuscany (Italy) from April to November 2004 on 108 sheep with the aim to identify the most resistant subjects to Coccidia. Moreover, the presence of gastro-intestinal Strongylids, Dicrocoelium sp. Moniezia spp.Strongyloides sp. and Trichuris sp. was also evaluated. Sheep selection may be based on OPG in adults animals, as it appears to be an indicator of sheep resistance to Coccidia. Before incorporating the parameter into breeding programmes, however, it is necessary to better appraise the degree of infestation of the other parasites as it may be difficult to select simultaneously for resistance to Coccidia and Strongylids unless the genetic correlation between these two traits is calculated and a selection index approach is used
7D Randall-Sundrum cosmology, brane-bulk energy exchange and holography
We discuss the cosmological implications and the holographic dual theory of
the 7D Randall-Sundrum (RS) gravitational set-up. Adding generic matter in the
bulk on the 7D gravity side we study the cosmological evolution inferred by the
non vanishing value of the brane-bulk energy exchange parameter. This analysis
is achieved in detail for specific assumptions on the internal space evolution,
including analytical considerations and numerical results. The dual theory is
then constructed, making use of the holographic renormalization procedure. The
resulting renormalized 6D CFT is anomalous and coupled to 6D gravity plus
higher order corrections. The critical point analysis on the brane is
performed. Finally, we sketch a comparison between the two dual descriptions.
We moreover generalize the AdS/CFT dual theory to the non conformal and
interacting case, relating the energy exchange parameter of the bulk gravity
description to the new interactions between hidden and visible sectors.Comment: 82 pages, 6 figures. Version accepted for publication; clarifications
added in eq.(4), section VII.D, below eq.(102) and in appendix A; references
adde
Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression
Background: Glioblastoma (GBM) is the most frequent and malignant primary brain tumor in adults and despite the progress in surgical procedures and therapy options, the overall survival remains very poor. Glutamate and α-KG are fundamental elements necessary to support the growth and proliferation of GBM cells. Glutamate oxidative deamination, catalyzed by GLUD2, is the predominant pathway for the production of α-KG. Methods: GLUD2 emerged from the RNA-seq analysis of 13 GBM patients, performed in our laboratory and a microarray analysis of 77 high-grade gliomas available on the Geo database. Thereafter, we investigated GLUD2 relevance in cancer cell behavior by GLUD2 overexpression and silencing in two different human GBM cell lines. Finally, we overexpressed GLUD2 in-vivo by using zebrafish embryos and monitored the developing central nervous system. Findings: GLUD2 expression was found associated to the histopathological classification, prognosis and survival of GBM patients. Moreover, through in-vitro functional studies, we showed that differences in GLUD2 expression level affected cell proliferation, migration, invasion, colony formation abilities, cell cycle phases, mitochondrial function and ROS production. In support of these findings, we also demonstrated, with in-vivo studies, that GLUD2 overexpression affects glial cell proliferation without affecting neuronal development in zebrafish embryos. Interpretation: We concluded that GLUD2 overexpression inhibited GBM cell growth suggesting a novel potential drug target for control of GBM progression. The possibility to enhance GLUD2 activity in GBM could result in a blocked/reduced proliferation of GBM cells without affecting the survival of the surrounding neurons
Enhancing the top signal at Tevatron using Neural Nets
We show that Neural Nets can be useful for top analysis at Tevatron. The main
features of and background events on a mixed sample are projected in
a single output, which controls the efficiency and purity of the
signal.Comment: 11 pages, 6 figures (not included and available from the authors),
Latex, UB-ECM-PF 94/1
Correlational Origin of the Roton Minimum
We present compelling evidence supporting the conjecture that the origin of
the roton in Bose-condensed systems arises from strong correlations between the
constituent particles. By studying the two dimensional bosonic dipole systems a
paradigm, we find that classical molecular dynamics (MD) simulations provide a
faithful representation of the dispersion relation for a low- temperature
quantum system. The MD simulations allow one to examine the effect of coupling
strength on the formation of the roton minimum and to demonstrate that it is
always generated at a sufficiently high enough coupling. Moreover, the
classical images of the roton-roton, roton-maxon, etc. states also appear in
the MD simulation spectra as a consequence of the strong coupling.Comment: 7 pages, 4 figure
A human MMTV-like betaretrovirus linked to breast cancer has been present in humans at least since the Copper Age
The betaretrovirus Mouse Mammary Tumor Virus (MMTV) is the well characterized etiological agent of mammary tumors in mice. In contrast, the etiology of sporadic human breast cancer (BC) is unknown, but accumulating data indicate a possible viral origin also for these malignancies. The presence of MMTVenv-like sequences (MMTVels) in the human salivary glands and saliva supports the latter as possible route of interhuman dissemination. In the absence of the demonstration of a mouse-man transmission of MMTV, we considered the possibility that a cross-species transmission could have occurred in ancient times. Therefore, we investigated MMTVels in the ancient dental calculus, which originates from saliva and is an excellent material for paleovirology. The calculus was collected from 36 ancient human skulls, excluding any possible mouse contamination. MMTV-like sequences were identified in the calculus of 6 individuals dated from the Copper Age to the 17th century. The MMTV-like sequences were compared with known human endogenous betaretroviruses and with animal exogenous betaretroviruses, confirming their exogenous origin and relation to MMTV. These data reveal that a human exogenous betaretrovirus similar to MMTV has existed at least since 4,500 years ago and indirectly support the hypothesis that it could play a role in human breast cancer
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