DCIS arising in mammary hamartoma

Mammary hamartoma is benign lesion and relatively rare. 17 cases of breast cancer associated with a hamartoma had been previously documented in the literature. We describe herein a case of noninvasive ductal carcinoma of the breast arising in hamartoma in a woman of 60’s. The discordance of images of the mass between mammogram and ultrasonogram can lead us to detect the carcinoma within the hamartoma in our case

O pesquisador como um “marinheiro de primeira viagem”: relatos de uma pesquisa de inspiração antropológica na administração

This work aims to show the first experience with an anthropologically inspired research of PhD students from Management course, who researched the daily routine of beauty salons in the city of São Paulo. 120 hours of observation were made during three months. The data obtained from the field notes and the data analysis was conducted by grounded theory. This inaugural experience of the PhD students contributes to the debate about ethnographic research in the management field and about research practice in the researcher training process.Este trabalho tem como objetivo apresentar a primeira experiência com pesquisa de inspiração antropológica de estudantes de doutorado em administração, investigando o cotidiano de salões de beleza na cidade de São Paulo. Foram realizadas 120 horas de observação durante três meses. Os dados resultaram das notas de campo e a análise dos dados foi conduzida pela grounded theory. Essa vivência inaugural das doutorandas contribui com o debate sobre a pesquisa etnográfica no campo da administração e sobre a experiência de pesquisa no processo de formação do pesquisador

DIP during perioperative chemotherapy

Purpose : Drug-induced interstitial pneumonia (DIP) that occurs during chemotherapy for breast cancer is a rare but a serious adverse event. Treatments of DIP requires interruption of breast cancer treatment, which may affect the patient’s prognosis. However, there are few reports which discuss DIP during breast cancer treatments. Purpose of this report is to make clear how DIP occurred and influenced breast cancer treatment in our hospital. Patients and Methods : A total of 74 patients who started perioperative chemotherapy in Tokushima Municipal Hospital for breast cancer from January 2019 to December 2020 were evaluated for DIP. Patients’ and tumors’ characteristics, and regimens which caused DIP were investigated. The clinical courses of the DIP patients were also followed up. Results : Twelve of the 74 patients developed DIP. All 12 patients had histories of cyclophosphamide administration ; however, the causative drug could not be determined. Ten of the 12 patients were treated with steroids, and all the patients recovered ultimately from the interstitial pneumonia. While chemotherapy was administered in six patients after mild DIP, no relapse of pneumonia was observed. Conclusion : DIP during perioperative chemotherapy for breast cancer was resolved with appropriate treatment. Patients were able to resume breast cancer treatment with minimal interruption

The researcher as a ?landlubber? : reports from an anthropologically inspired research in management.

Este trabalho tem como objetivo apresentar a primeira experi?ncia com pesquisa de inspira??o antropol?gica de estudantes de doutorado em administra??o, investigando o cotidiano de sal?es de beleza na cidade de S?o Paulo. Foram realizadas 120 horas de observa??o durante tr?s meses. Os dados resultaram das notas de campo e a an?lise dos dados foi conduzida pela grounded theory. Essa viv?ncia inaugural das doutorandas contribui com o debate sobre a pesquisa etnogr?fica no campo da administra??o e sobre a experi?ncia de pesquisa no processo de forma??o do pesquisador.This work aims to show the first experience with an anthropologically inspired research of PhD students from Management course, who researched the daily routine of beauty salons in the city of S?o Paulo. 120 hours of observation were made during three months. The data obtained from the field notes and the data analysis was conducted by grounded theory. This inaugural experience of the PhD students contributes to the debate about ethnographic research in the management field and about research practice in the researcher training process

Eighteen Coral Genomes Reveal the Evolutionary Origin of Acropora Strategies to Accommodate Environmental Changes

The genus Acropora comprises the most diverse and abundant scleractinian corals (Anthozoa, Cnidaria) in coral reefs, the most diverse marine ecosystems on Earth. However, the genetic basis for the success and wide distribution of Acropora are unknown. Here, we sequenced complete genomes of 15 Acropora species and 3 other acroporid taxa belonging to the genera Montipora and Astreopora to examine genomic novelties that explain their evolutionary success. We successfully obtained reasonable draft genomes of all 18 species. Molecular dating indicates that the Acropora ancestor survived warm periods without sea ice from the mid or late Cretaceous to the Early Eocene and that diversification of Acropora may have been enhanced by subsequent cooling periods. In general, the scleractinian gene repertoire is highly conserved; however, coral- or cnidarian-specific possible stress response genes are tandemly duplicated in Acropora. Enzymes that cleave dimethlysulfonioproprionate into dimethyl sulfide, which promotes cloud formation and combats greenhouse gasses, are the most duplicated genes in the Acropora ancestor. These may have been acquired by horizontal gene transfer from algal symbionts belonging to the family Symbiodiniaceae, or from coccolithophores, suggesting that although functions of this enzyme in Acropora are unclear, Acropora may have survived warmer marine environments in the past by enhancing cloud formation. In addition, possible antimicrobial peptides and symbiosis-related genes are under positive selection in Acropora, perhaps enabling adaptation to diverse environments. Our results suggest unique Acropora adaptations to ancient, warm marine environments and provide insights into its capacity to adjust to rising seawater temperatures

Distance to Orion KL Measured with VERA

We present the initial results of multi-epoch VLBI observations of the 22 GHz H2O masers in the Orion KL region with VERA (VLBI Exploration of Radio Astrometry). With the VERA dual-beam receiving system, we have carried out phase-referencing VLBI astrometry and successfully detected an annual parallax of Orion KL to be 2.29+/-0.10 mas, corresponding to the distance of 437+/-19 pc from the Sun. The distance to Orion KL is determined for the first time with the annual parallax method in these observations. Although this value is consistent with that of the previously reported, 480+/-80 pc, which is estimated from the statistical parallax method using proper motions and radial velocities of the H2O maser features, our new results provide the much more accurate value with an uncertainty of only 4%. In addition to the annual parallax, we have detected an absolute proper motion of the maser feature, suggesting an outflow motion powered by the radio source I along with the systematic motion of source I itself.Comment: 7 pages, 3 figures. PASJ, in press (Vol. 59, No. 5, October 25, 2007 issue

Absolute Proper Motions of H2O Masers Away from the Galactic Plane Measured with VERA in the "Superbubble" Region NGC 281

We report on absolute proper-motion measurements of an H2O maser source in the NGC 281 West molecular cloud, which is located ~320 pc above the Galactic plane and is associated with an HI loop extending from the Galactic plane. We have conducted multi-epoch phase-referencing observations of the maser source with VERA (VLBI Exploration of Radio Astrometry) over a monitoring period of 6 months since May 2006. We find that the H2O maser features in NGC 281 West are systematically moving toward the southwest and further away from the Galactic plane with a vertical velocity of ~20-30 km/s at its estimated distance of 2.2-3.5 kpc. Our new results provide the most direct evidence that the gas in the NGC 281 region on the HI loop was blown out from the Galactic plane, most likely in a superbubble driven by multiple or sequential supernova explosions in the Galactic plane.Comment: 10 pages, 5 figures, PASJ in press (Vol. 59, No. 4; August 25, 2007 issue

VLBI Astrometry of AGB Variables with VERA -- A Semiregular Variable S Crateris --

We present a distance measurement for the semiregular variable S Crateris (S Crt) based on its annual parallax. With the unique dual beam system of the VLBI Exploration for Radio Astrometry (VERA) telescopes, we measured the absolute proper motion of a water maser spot associated with S Crt, referred to the quasar J1147-0724 located at an angular separation of 1.23$^{\circ}$. In observations spanning nearly two years, we have detected the maser spot at the LSR velocity of 34.7 km s$^{-1}$, for which we measured the annual parallax of 2.33$\pm$0.13 mas corresponding to a distance of 430$^{+25}_{-23}$ pc. This measurement has an accuracy one order of magnitude better than the parallax measurements of HIPPARCOS. The angular distribution and three-dimensional velocity field of maser spots indicate a bipolar outflow with the flow axis along northeast-southwest direction. Using the distance and photospheric temperature, we estimate the stellar radius of S Crt and compare it with those of Mira variables.Comment: 9 pages, 4 figures, accepted for publication in PASJ (Vol.60, No.5, October 25, VERA special issue

Comparison of Dielectric Properties between Epoxy Composites with Nanosized Clay Fillers Modified by Primary Amine and Tertiary Amine (Final draft (Post-print) version)

Epoxy-based nanocomposites (NCs) were prepared using clay modified by either primary amine or tertiary amine, and the effect of the difference in modifier on the thermal and dielectric properties of the NCs were discussed. The NC with clay fillers modified by the primary amine, 1C, shows a glass transition end temperature (Teg) at a temperature 20°C lower than the neat epoxy (N). This indicates that the resin of 1C is less crosslinked than that of N. On the other hand, the sample 3C, in which the clay was modified by the tertiary amine, shows a DSC spectrum close to that of N. Namely, 3C has a high crosslinking density similar to N. While the three samples show a relaxation peak in their dielectric loss spectra, the peak appears at high frequencies in 1C compared to N and 3C. Moreover, ionic conduction current flows more at high temperatures in 1C than in N or 3C. These facts are ascribable to the difference in their crosslinking densities

学生観点による学習意欲を促進させる動機づけ因子 －混合研究法を用いて－

　学習意欲を促進させる動機づけ因子を学生観点から抽出しその影響を明確にするために、混合研究法の探索的順次デザインを用いて研究を行った。第１フェーズでは、A県内看護系３大学に所属する２～４年次生23名に半構造化面接を行い、質的帰納的に分析した。学生の学習意欲を促進させる動機づけ因子は、【良い看護師になるため】【科目に対する個人的な興味関心】【先を見越した計画的な学習】【試験合格や成績良好を目指して】【他者の学習姿勢から受ける刺激】の５カテゴリーであった。第２フェーズでは、第１フェーズの結果に基づいて作成した動機づけ尺度を用いて、学生が影響を受けている動機づけの段階を明確にした。看護系２大学に所属する２～４年次生500名に協力を依頼し、165名（回収率33％）から回答を得た。多くの学生は、罪悪感解消や承認獲得の願望、外部からの圧力や報酬、学習自体への興味関心が学習の動機づけとなっていることが示唆された