10 research outputs found
IMPACT-Global Hip Fracture Audit: Nosocomial infection, risk prediction and prognostication, minimum reporting standards and global collaborative audit. Lessons from an international multicentre study of 7,090 patients conducted in 14 nations during the COVID-19 pandemic
Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14路2 per cent (646 of 4544) and the 30-day mortality rate was 1路8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7路61, 95 per cent c.i. 4路49 to 12路90; P < 0路001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0路65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability
Opera omnia medico-physica, tractatibus quinque comprehensa ... - Editio novissima, figuris aeneis adornata.
Universit脿 degli Studi di Triest
Rhachitidologia, or, A tract of the disease rhachitis, commonly called the rickets shewing the signes, cause, symptoms, and prognosticks : together with a most accurate and ingenious method of cure / written originally in Latin ... by ... Dr. John Mayow ... and now ... faithfully rendred into English by W.S. ; to which is subjoyn'd a profitable appendix, touching weights and measures us'd in the composition of medicines and exhibition of medicinal doses.
Tractatus quinque medico-physici. [electronic resource] : Quorum primus agit de sal-nitro, et spiritu nitro-aereo. Secundus de respiratione. Tertius de respiratione foetus in utero, et ovo. Quartus de motu musculari, et spiritibus animalibus. Ultimus de rhachitide. Studio Joh. Mayow LL.D. & medici: necnon Coll. Omn. Anim. in Univ. Oxon. Socii.
Fragment; consists of t.p. only.Reproduction of original in: British Library.Wing (CD-ROM, 1996)MadanEarly English books tract supplement interim guideElectronic reproduction
Device for Attaching Horseshoes.
Patent for a new and improved device for attaching horseshoes. This design "relates to improvements in means for attaching shoes to the hoofs of horses or mules without the use of nails; and the invention consists in . . . a nailless shoe [that] can be firmly and securely attached to the foot and detached therefrom without requiring the services of a smith" (lines 9-18). To this end, it consists in "the combination, with the shoe-plate and the toe-plate, of the toe-bar having a flange to engage the toe-plate, the bits, half-bands, and clamping-bolts" (lines 61-65)
Traduction des oeuvres chimiques et physiologiques de Jean Mayow,... / par L茅op. Ledru,... et H. C. Gaubert,...
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