57 research outputs found
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Development of responsible tourism guidelines for South Africa (Final report)
This project aimed to identify a system by which the aspirations laid out in a specific government policy document could be presented in a way that the private sector and rural communities can use it to manage business at the operational local level. The model aimed to demonstrate how civil society could use the new responsible tourism policy criteria that exist to structure management and leverage government support and to guide and benchmark the achievement against economic (pro-poor) social and environmental criteria. The project was designed to: 1. translate stakeholder agreed government policy into practical management guidelines for the whole tourism industry; 2. develop, test and adapt the guidelines in the most directly relevant sector for rural livelihoods impact, that of nature based tourism - applicable across significant areas of South Africa and far beyond the boundaries of national parks; 3. pilot the guidelines as a system of monitoring against criteria and measurable indicators that have recently been developed by South African National Parks within the lodge concession leasing process
NASA 2018 Green Propulsion Roadmap
The Green Propulsion Working Group (GPWG) is a technical guidance working group formed April 2017 under the Agency's Capability Leadership Team The GPWG was tasked with recommending an agency road map and providing guidance to NASA on green propulsion technology development and infusion The GPWG's efforts focus on ionic liquid propellants and related technologies The GPWG was chartered with three representatives from NASA Centers currently exploring green propulsion technologies As other Centers may explore programs that utilize green propulsion, membership of the working group can be expanded to include more interested parties Working group also solicits and coordinates with other government agencies (e.g. AFRL, MDA) In 2015, JANNAF hosted a Technical Interchange Meeting (TIM) on Green Monopropellant Alternatives to Hydrazine (GMAH) Included both Government and non-Government contributions on the State-of-the-Art in Green Propulsion Technology Following the TIM, a Government-only session (USAF/AFRL/NASA/MDA/DLA) reviewed and identified remaining technical gaps in Green Propulsion In 2016, an inter-agency team (AFRL/NASA/MDA) worked together to develop an informal inter-agency "roadmap" based on the outcome of the TIM Approach consisted of near-term, mid-term, and long-term technology advancement areas, approaching incrementally larger thrust classes The NASA Green Propulsion Working Group reviewed the work of the 2016 Inter-Agency Working Group, and concurs that the identified technical gaps and technology development areas are still relevant and necessary to see green propulsion technology advanced The GPWG recommends the 2016 roadmap be adopted as baseline for NASA needs, with some additions The focus of the 2016 inter-agency roadmap was primarily on the thruster technology. The Agency must also invest in understanding the broader propulsion system-level technology gaps in parallel. Timeframes are considered suggested from a priority standpoint, but are also flexible as some efforts will need to occur in the nearer term or concurrently in order to meet specific mission requirements The GPWG developed 2018 roadmap breaks down the technology development goals into Technology Development Areas (TDA's), and identifies the near-, mid, and long-term sub-goals within those areas. Those TDA's are: Thruster Hardware Development Modeling & Tools Development Materials Properties and Compatibility Propellant Development
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Ethical trade and sustainable rural livelihoods
The growth in interest in ethical trade has raised many questions. This publication seeks to answer four of the most basic of these: what do we mean by ethical trade and the ethical market, particularly in relation to natural resources? How does ethical trade operate? Who benefits from ethical trade and how? Is it a useful developmental approach
The Grizzly, February 28, 1995
Core Changes Proposed: Public Speaking, ESS 100, and Fine Arts in Question âą Delta Pi Suspended âą Ursinus Prepares for Spring Service Day âą Letter from Dean Kane âą Airband âą S.T.A.R. to Sponsor Sexual Assault Awareness Week âą The Sculpture Population Boom âą Spirit, Black and Female Celebrates Black History Month âą How We Pick Our Entertainers âą Letters to the Editor âą Humiliation âą Luka is ECAC Gymnast of the Week âą Cauley Seeded 14th at Nationals âą Ortman is Going to Nationals âą Bears Open Up in Cocoa on Saturday âą Caggiano, Laidlaw, and Widmaier Win Indoor Track Titles âą Cosgrove Named Centennial Player of the Year âą Ursinus Wins First-Ever Women\u27s Hoop Titlehttps://digitalcommons.ursinus.edu/grizzlynews/1355/thumbnail.jp
Finishing the euchromatic sequence of the human genome
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers âŒ99% of the euchromatic genome and is accurate to an error rate of âŒ1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
Obituaries: M - Ma Folder
105 pages of subject files containing and related to Obituaries: M - M
Bridge-in-a-Backpackâą Task 3.2: Investigate Soil-Structure Interaction â Modeling and Experimental Results of Steel Arches, 2016
Bridge-in-a-Backpackâą Task 3.1: Investigate Soil-Structure Interaction â Experimental Design, 2016
Fostering connections between University Hill Secondary School and the UBC Farm
University Hill Secondary School (UHSS), located in Vancouver, British
Columbia, will be moving to a new building near the UBC Farm. The UBC Farm is a
research and educational facility located on UBC campus. This report aims to help the
UHSS Home Economics teacher, Ellen Walker, reconnect her students with food,
ecological systems, and the environment through new curriculum ideas for her Home
Economics classes that utilize the resources of the UBC Farm. This project began with a
primary literature review followed by the decision to focus on a âfallâ theme in order to
collaborate with a second LFS group assigned to this project. We met with our
stakeholders: the Land and Food System (LFS) teaching team, Ellen Walker and the
students of UHSS, and Mark Bomford of the UBC Farm. The result of this project was
three lesson plans (topics: chickens and eggs, apples, and pumpkins) which address the
knowledge disconnect between farm and plate, tie into Ms. Walkerâs existing lesson
plans, and outline the many of BC Ministry of Educationâs Prescribed Learning
Outcomes given for grades 10-12 that they meet. Through our adapted lesson plans,
students will acquire a greater understanding of the food system as well as gain hands-on
learning opportunities at the UBC Farm. Three recommendations were given with clear
and timely goals which aim to establish a lasting and meaningful connection between
UHSS and the UBC Farm. First, we hope the connection is initiated with a minimum of
two farm visits in the upcoming school year. We then hope UHSS encourages extracurricular
student participation, and that future LFS student groups evaluate the progress
to determine the success of and potential for expansion on these adapted lesson plans. Disclaimer: âUBC SEEDS provides students with the opportunity to share the findings of their studies, as well as their opinions, conclusions and recommendations with the UBC community. The reader should bear in mind that this is a student project/report and is not an official document of UBC. Furthermore readers should bear in mind that these reports may not reflect the current status of activities at UBC. We urge you to contact the research persons mentioned in a report or the SEEDS Coordinator about the current status of the subject matter of a project/report.âLand and Food Systems, Faculty ofUnreviewedUndergraduat
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