Three issues for mental health nurse educators preparing new preregistration programmes

Universities across the UK must develop and have in place new preregistration programmes by 2020. Unlike in the rest of the world, where initial nurse preparation is generic, preregistration education in the UK allows students to specialize in one of four specific fields of practice - adult, mental health, child or learning disability. To the relief of many , the new standards confirmed the continued survival of the specialist fields at undergraduate level. Educators across the UK now have an opportunity to fully review existing provision and address areas of significance. This paper explores three such issues. These are: •How best to respond to adverse life experiences or trauma.•The ethical tension which we believe is inherent in the use of coercive practice.•The potential to make a difference to the appalling mortality statistics which indicate that people with long standing mental health problems die much younger than their contemporaries In each case we make tentative suggestions for how they might be approached

A homotopy-theoretic view of Bott-Taubes integrals and knot spaces

We construct cohomology classes in the space of knots by considering a bundle over this space and "integrating along the fiber" classes coming from the cohomology of configuration spaces using a Pontrjagin-Thom construction. The bundle we consider is essentially the one considered by Bott and Taubes, who integrated differential forms along the fiber to get knot invariants. By doing this "integration" homotopy-theoretically, we are able to produce integral cohomology classes. We then show how this integration is compatible with the homology operations on the space of long knots, as studied by Budney and Cohen. In particular we derive a product formula for evaluations of cohomology classes on homology classes, with respect to connect-sum of knots.Comment: 32 page

Law Casebook Description and Table of Contents: Constitutional Environmental and Natural Resources Law [outline]

6 pages. James May, Widener University School of Law -- Agend

Law Casebook Description and Table of Contents: Constitutional Environmental and Natural Resources Law [outline]

6 pages. James May, Widener University School of Law -- Agend

Host-Microbe Interactions : Fungi

Peer reviewedPostprin

Antecedents, moderators and examples of representational predicaments at three Hong Kong sites

Employees suffer representational predicaments if they feel that they bear invisible burdens and/or make invisible contributions. This feeling implies a belief that dominant authorities in the organization are embracing unfavourable prevai1ing images of employees (PIEs) that are incongruent with salient work-life space domains. Qualitative interviews at an insurance agency branch and an on-line database provider indicated embedded human resource values characterized by aggressive instrumentality, small circle and top down govemance, and expectations of employee deference and silence. These values reflected the Hong Kong human resource govemance environment: absence of labour rights and protections, and cultural assumptions of large power distance, high masculinity and networkorientation. Our grounded model proposes that these antecedents led to representational climates that were not characterized by high-fidelity meritocracy, in tum exposing employees to the risk of representational predicaments. Individuals\u27 compatibility with embedded values and their relational proximity to dominant authorities appeared to reduce this risk, while proximal appreciation/support and diligent beliefs appeared to offset distress arising 企om representational predicaments. At a third site, the administrative side of a tertiary education institute, dominant authorities\u27 non-conformist values and best practice open govemance benchmarking appeared to moderate the impact of the Hong Kong human resource govemance environment, leading to relatively high-fidelity meritocracy and less risk of representational predicaments

My Cutey\u27s Due at Two-to-Two To-day

With Ukulele arrangement. Contains advertisements and/or short musical examples of pieces being sold by publisher.https://digitalcommons.library.umaine.edu/mmb-vp/7166/thumbnail.jp

Application of high-field asymmetric waveform ion mobility separation to LESA mass spectrometry of bacteria

We have previously demonstrated the analysis of intact proteins directly from bacterial colonies (including Gram-negative and Gram-positive clinical isolates) grown on agar media by liquid extraction surface analysis mass spectrometry (LESA MS). Several challenges were identified in that work, including (1) interference of background signal derived from the nutrient media (<i>Escherichia coli</i>), (2) a high density of protein peaks leading to the isolation of multiple protein precursor ions in a single window and consequent acquisition of composite tandem mass spectra (<i>Pseudomonas aeruginosa</i>), and (3) the overabundance of secreted peptides suppressing peaks corresponding to proteins (<i>Staphylococcus aureus</i>). Here, we present the coupling of high-field asymmetric waveform ion mobility spectrometry (FAIMS) separation into the LESA MS protocol, with the aim of resolving the aforementioned challenges and thus improving the capabilities of LESA MS for bacterial characterization. The results show that inclusion of FAIMS expands the range of detected proteins through separation of background peaks from protein signal, as well as through resolution of overlapping protein peaks which could not previously be isolated by LESA MS alone

The Cryptococcus gattii species complex:Unique pathogenic yeasts with understudied virulence mechanisms

Members of Cryptococcus gattii/neoformans species complex are the etiological agents of the potentially fatal human fungal infection cryptococcosis. C. gattii and its sister species cause disease in both immunocompetent and immunocompromised hosts, while the closely related species C. neoformans and C. deneoformans predominantly infect immunocompromised hosts. To date, most studies have focused on similarities in pathogenesis between these two groups, but over recent years, important differences have become apparent. In this review paper, we highlight some of the major phenotypic differences between the C. gattii and neoformans species complexes and justify the need to study the virulence and pathogenicity of the C. gattii species complex as a distinct cryptococcal group.</p