A Novel Efficient Dynamic Throttling Strategy for Blockchain-Based Intrusion Detection Systems in 6G-Enabled VSNs

Vehicular Social Networks (VSNs) have emerged as a new social interaction paradigm, where vehicles can form social networks on the roads to improve the convenience/safety of passengers. VSNs are part of Vehicle to Everything (V2X) services, which is one of the industrial verticals in the coming sixth generation (6G) networks. The lower latency, higher connection density, and near-100% coverage envisaged in 6G will enable more efficient implementation of VSNs applications. The purpose of this study is to address the problem of lateral movements of attackers who could compromise one device in a VSN, given the large number of connected devices and services in VSNs and attack other devices and vehicles. This challenge is addressed via our proposed Blockchain-based Collaborative Distributed Intrusion Detection (BCDID) system with a novel Dynamic Throttling Strategy (DTS) to detect and prevent attackers’ lateral movements in VSNs. Our experiments showed how the proposed DTS improve the effectiveness of the BCDID system in terms of detection capabilities and handling queries three times faster than the default strategy with 350k queries tested. We concluded that our DTS strategy can increase transaction processing capacity in the BCDID system and improve its performance while maintaining the integrity of data on-chain

Integrated graphene patch antenna for communications at THz frequencies

Graphene is an attractive material for communications in the THz range due to its ability to support surface plasmon polaritons. This enables a graphene antenna to be smaller in size than its metallic counterpart. In addition, the possibility to control the graphene conductivity during operation by an applied bias leads to the tunability of the resonant frequency of graphene antennas. Graphene-based antennas integrated into transceivers working at THz frequencies may lead to faster and more efficient devices. In this work, we design and simulate a graphene patch antenna that can be integrated into transceivers by through-substrate vias. The tuning of the resonant frequency is also studied by simulations.This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement N° 863337.Peer ReviewedPostprint (author's final draft

Blockchain-enabled Intrusion Detection and Prevention System of APTs within Zero Trust Architecture

In a world where organisations are embracing new IT working models such as Bring Your Own Device (BYOD) and remote working, the traditional mindset of defending the network perimeter is no longer sufficient. Zero Trust Architecture (ZTA) has recently emerged as a new security model in which the breach mindset dominates the threat model. By default, the ZTA considers any endpoint (i.e., device), user, or application to be untrusted until proven otherwise. Nonetheless, once proven by the endpoint, using Advanced Persistent Threats (APT), attackers can still take over an authenticated and authorised session via that endpoint. Therefore, they can perform several user/device centric malicious activities in addition to lateral movement rendering the endpoint the Achilles heel of ZTA. To effectively deter APT attack capabilities on the endpoints, this work proposes a Blockchain-enabled Intrusion Detection and Prevention System (BIDPS) that augments ZTA onto endpoints. The BIDPS aims to achieve two core outcomes: first, detect and prevent attackers’ techniques and tactics as per MITRE’s ATT&CK enterprise matrix earlier than the lateral movement stage, and secondly, strip trust out of the endpoint itself and place it on-chain, thus creating an immutable system of explicit trust. To evaluate the effectiveness of the BIDPS, a testbed was built where techniques of over ten APTs attacks were launched against the endpoint. BIDPS has a high rate of success defending against the launched attacks owing to its Blockchain’s immutability, fortifying the detection/prevention processes

Chromosome 1p13 genetic variants antagonize the risk of myocardial infarction associated with high ApoB serum levels

PMCID: PMC3480949This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Socioeconomic predictors and consequences of depression among primary care attenders with non-communicable diseases in the Western Cape, South Africa:Cohort study within a randomised trial

Background: Socioeconomic predictors and consequences of depression and its treatment were investigated in 4393 adults with specified non-communicable diseases attending 38 public sector primary care clinics in the Eden and Overberg districts of the Western Cape, South Africa.   Methods: Participants were interviewed at baseline in 2011 and 14 months later, as part of a randomised controlled trial of a guideline-based intervention to improve diagnosis and management of chronic diseases. The 10-item Center for Epidemiologic Studies Depression Scale (CESD-10) was used to assess depression symptoms, with higher scores representing more depressed mood. Results: Higher CESD-10 scores at baseline were independently associated with being less educated (p=0.004) and having lower income (p=0.003). CESD-10 scores at follow-up were higher in participants with less education (p=0.010) or receiving welfare grants (p=0.007) independent of their baseline scores. Participants with CESD-10 scores of 10 or more at baseline (56% of all participants) had 25% higher odds of being unemployed at follow-up (p=0.016), independently of baseline CESD-10 score and treatment status. Among participants with baseline CESD-10 scores of 10 or more, antidepressant medication at baseline was independently more likely in participants who had more education (p=0.002), higher income (p<0.001), or were unemployed (p=0.001). Antidepressant medication at follow up was independently more likely in participants with higher income (p=0.023), and in clinics with better access to pharmacists (p=0.053) and off-site drug delivery (p=0.013).  Conclusions: Socioeconomic disadvantage appears to be both a cause and consequence of depression, and may also be a barrier to treatment. There are opportunities for improving the prevention, diagnosis and treatment of depression in primary care in inequitable middle income countries like South Africa.  Trial registration: The trial is registered with Current Controlled Trials (ISRCTN20283604) and the Office for Human Research Protections Database (IRB00001938, FWA00001637)

The usefulness of rapid diagnostic tests in the new context of low malaria transmission in zanzibar.

BACKGROUND\ud \ud We assessed if histidine-rich-protein-2 (HRP2) based rapid diagnostic test (RDT) remains an efficient tool for Plasmodium falciparum case detection among fever patients in Zanzibar and if primary health care workers continue to adhere to RDT results in the new epidemiological context of low malaria transmission. Further, we evaluated the performance of RDT within the newly adopted integrated management of childhood illness (IMCI) algorithm in Zanzibar.\ud \ud METHODS AND FINDINGS\ud \ud We enrolled 3890 patients aged ≥2 months with uncomplicated febrile illness in this health facility based observational study conducted in 12 primary health care facilities in Zanzibar, between May-July 2010. One patient had an inconclusive RDT result. Overall 121/3889 (3.1%) patients were RDT positive. The highest RDT positivity rate, 32/528 (6.1%), was found in children aged 5-14 years. RDT sensitivity and specificity against PCR was 76.5% (95% CI 69.0-83.9%) and 99.9% (95% CI 99.7-100%), and against blood smear microscopy 78.6% (95% CI 70.8-85.1%) and 99.7% (95% CI 99.6-99.9%), respectively. All RDT positive, but only 3/3768 RDT negative patients received anti-malarial treatment. Adherence to RDT results was thus 3887/3889 (99.9%). RDT performed well in the IMCI algorithm with equally high adherence among children <5 years as compared with other age groups.\ud \ud CONCLUSIONS\ud \ud The sensitivity of HRP-2 based RDT in the hands of health care workers compared with both PCR and microscopy for P. falciparum case detection was relatively low, whereas adherence to test results with anti-malarial treatment was excellent. Moreover, the results provide evidence that RDT can be reliably integrated in IMCI as a tool for improved childhood fever management. However, the relatively low RDT sensitivity highlights the need for improved quality control of RDT use in primary health care facilities, but also for more sensitive point-of-care malaria diagnostic tools in the new epidemiological context of low malaria transmission in Zanzibar.\ud \ud TRIAL REGISTRATION\ud \ud ClinicalTrials.gov NCT01002066

Graphene-based Wireless Agile Interconnects for Massive Heterogeneous Multi-chip Processors

The main design principles in computer architecture have recently shifted from a monolithic scaling-driven approach to the development of heterogeneous architectures that tightly co-integrate multiple specialized processor and memory chiplets. In such data-hungry multi-chip architectures, current Networks-in-Package (NiPs) may not be enough to cater to their heterogeneous and fast-changing communication demands. This position paper makes the case for wireless in-package nanonetworking as the enabler of efficient and versatile wired-wireless interconnect fabrics for massive heterogeneous processors. To that end, the use of graphene-based antennas and transceivers with unique frequency-beam reconfigurability in the terahertz band is proposed. The feasibility of such a nanonetworking vision and the main research challenges towards its realization are analyzed from the technological, communications, and computer architecture perspectives.Comment: 8 pages, 4 figures, 1 table - Accepted at IEEE Wireless Communications Magazin

Binary and Millisecond Pulsars at the New Millennium

We review the properties and applications of binary and millisecond pulsars. Our knowledge of these exciting objects has greatly increased in recent years, mainly due to successful surveys which have brought the known pulsar population to over 1300. There are now 56 binary and millisecond pulsars in the Galactic disk and a further 47 in globular clusters. This review is concerned primarily with the results and spin-offs from these surveys which are of particular interest to the relativity community.Comment: 59 pages, 26 figures, 5 tables. Accepted for publication in Living Reviews in Relativity (http://www.livingreviews.org

Gravitational Waves from Gravitational Collapse

Gravitational wave emission from the gravitational collapse of massive stars has been studied for more than three decades. Current state of the art numerical investigations of collapse include those that use progenitors with realistic angular momentum profiles, properly treat microphysics issues, account for general relativity, and examine non--axisymmetric effects in three dimensions. Such simulations predict that gravitational waves from various phenomena associated with gravitational collapse could be detectable with advanced ground--based and future space--based interferometric observatories.Comment: 68 pages including 13 figures; revised version accepted for publication in Living Reviews in Relativity (http://www.livingreviews.org