Constructional Volcanic Edifices on Mercury: Candidates and Hypotheses of Formation

Mercury, a planet with a predominantly volcanic crust, has perplexingly few, if any, constructional volcanic edifices, despite their common occurrence on other solar system bodies with volcanic histories. Using image and topographical data from the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft, we describe two small (< 15 km‐diameter) prominences with shallow summit depressions associated with volcanically flooded impact features. We offer both volcanic and impact‐related interpretations for their formation, and then compare these landforms with volcanic features on Earth and the Moon. Though we cannot definitively conclude that these landforms are volcanic, the paucity of constructional volcanic edifices on Mercury is intriguing in itself. We suggest that this lack is because volcanic eruptions with sufficiently low eruption volumes, rates, and flow lengths, suitable for edifice construction, were highly spatiotemporally restricted during Mercury's geological history. We suggest that volcanic edifices may preferentially occur in association with late‐stage, post‐impact effusive volcanic deposits. The ESA/JAXA BepiColombo mission to Mercury will be able to investigate further our candidate volcanic edifices, search for other, as‐yet unrecognized edifices beneath the detection limits of MESSENGER data, and test our hypothesis that edifice construction is favored by late‐stage, low‐volume effusive eruptions

Plasticizer degradation by marine bacterial isolates : a proteogenomic and metabolomic characterization

Many commercial plasticizers are toxic endocrine-disrupting chemicals that are added to plastics during manufacturing and may leach out once they reach the environment. Traditional phthalic acid ester plasticizers (PAEs), such as dibutyl phthalate (DBP) and bis(2-ethyl hexyl) phthalate (DEHP), are now increasingly being replaced with more environmentally friendly alternatives, such as acetyl tributyl citrate (ATBC). While the metabolic pathways for PAE degradation have been established in the terrestrial environment, to our knowledge, the mechanisms for ATBC biodegradation have not been identified previously and plasticizer degradation in the marine environment remains underexplored. From marine plastic debris, we enriched and isolated microbes able to grow using a range of plasticizers and, for the first time, identified the pathways used by two phylogenetically distinct bacteria to degrade three different plasticizers (i.e., DBP, DEHP, and ATBC) via a comprehensive proteogenomic and metabolomic approach. This integrated multi-OMIC study also revealed the different mechanisms used for ester side-chain removal from the different plasticizers (esterases and enzymes involved in the β-oxidation pathway) as well as the molecular response to deal with toxic intermediates, that is, phthalate, and the lower biodegrading potential detected for ATBC than for PAE plasticizers. This study highlights the metabolic potential that exists in the biofilms that colonize plastics-the Plastisphere-to effectively biodegrade plastic additives and flags the inherent importance of microbes in reducing plastic toxicity in the environment

The Impact of Program Changes on Enrollment, Access, and Utilization in the Oregon Health Plan Standard Population

In February 2003, in an effort to expand Medicaid coverage within tight fiscal constraints, the Oregon Health Plan (OHP) underwent a significant redesign of benefits, cost-sharing and premium structure. The OHP2 redesign resulted in two tiers of coverage, OHP Plus and OHP Standard, and a premium subsidy program. The OHP Plus benefit package and cost sharing structure is similar to the original OHP and serves the federally-mandated Medicaid populations: children and pregnant women, low-income elderly and individuals meeting the SSI definition of disability. OHP Standard, designed for Oregon’s expansion population,1 includes a reduced benefit package, expanded co-pays and increased premiums. Premium rules were also tightened for the OHP Standard group: individuals are now disqualified from benefits for non-payment of premiums and locked-out from OHP for six months following a disqualification. In addition, monthly premiums are no longer waived for certain groups.(e.g., homeless, zero income). In order to assess the impact of recent program changes, a mail-return survey was conducted between November 2003 and February 2004 with a random sample of OHP beneficiaries who were enrolled as of February 2003, immediately before the program changes were implemented. The survey assessed issues related to enrollment, health care access, health care use, and financial and health status and covered a six-month period following the OHP changes. A total of 2,783 individuals completed surveys, 1,405 individuals in OHP Plus and 1,378 in OHP Standard. This report presents descriptive survey results for the 1,378 OHP Standard enrollees and addresses the impact of recent program changes on 3 key outcomes: enrollment, health care access, and utilization

The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies

The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems. PNS glia respond rapidly to nerve injury by clearing debris from the injury site, supplying essential growth factors and providing structural support; all of which enhances neuronal regeneration. Thus, transplantation of glial cells from the PNS is a very promising therapy for injuries to both the PNS and the CNS. There are two key types of PNS glia: olfactory ensheathing cells (OECs), which populate the olfactory nerve, and Schwann cells (SCs), which are present in the rest of the PNS. These two glial types share many similar morphological and functional characteristics but also exhibit key differences. The olfactory nerve is constantly turning over throughout life, which means OECs are continuously stimulating neural regeneration, whilst SCs only promote regeneration after direct injury to the PNS. This review presents a comparison between these two PNS systems in respect to normal physiology, developmental anatomy, glial functions and their responses to injury. A thorough understanding of the mechanisms and differences between the two systems is crucial for the development of future therapies using transplantation of peripheral glia to treat neural injuries and/or disease.Griffith Health, School of Nursing and MidwiferyFull Tex

The effects of 180 years of aging on the physical and seismic properties of partially saturated sands

Author Posting. © American Geophysical Union, 2021. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Solid Earth 126(6), (2021): e2020JB021341, https://doi.org/10.1029/2020JB021341.Constraining how the physical properties and seismic responses of recently deposited sands change with time is important for understanding earthquake site response, subsurface fluid flow, and early stages of lithification. Currently, however, there is no detailed (cm-scale) assessment of how sand's physical properties and associated seismic velocities evolve over the first two centuries after deposition. Here, we integrate sedimentation rates with seismic velocity and sediment physical properties data to assess how the vadose zone sands at Port Royal Beach, Jamaica, change within 180 years after deposition. We show that compressional and shear wave velocities increase with sediment age, whereas porosity, grain size, sorting, mineralogy, and cementation fraction remain relatively unchanged during the same period. Rock physics models (constrained by the measured physical properties) predict constant seismic velocities at all sites regardless of sediment age, though misfits between modeled and observed velocities increase with sediment age. We explain these misfits by proposing that shallow sands undergo microstructural grain reorganization that leads to a more uniform distribution of grain contact forces with time. Our results imply that beach sands undergo a previously undocumented lithification process that occurs before compaction.The Society of Exploration Geophysicists Geoscientists without Borders Grant and the Institute for Earth, Science, and Man at Southern Methodist University partially supported this work

Relaxation dynamics of the Lieb-Liniger gas following an interaction quench: A coordinate Bethe-ansatz analysis

We investigate the relaxation dynamics of the integrable Lieb-Liniger model of contact-interacting bosons in one dimension following a sudden quench of the collisional interaction strength. The system is initially prepared in its noninteracting ground state and the interaction strength is then abruptly switched to a positive value, corresponding to repulsive interactions between the bosons. We calculate equal-time correlation functions of the nonequilibrium Bose field for small systems of up to five particles via symbolic evaluation of coordinate Bethe-ansatz expressions for operator matrix elements between Lieb-Liniger eigenstates. We characterize the relaxation of the system by comparing the time-evolving correlation functions following the quench to the equilibrium correlations predicted by the diagonal ensemble and relate the behavior of these correlations to that of the quantum fidelity between the many-body wave function and the initial state of the system. Our results for the asymptotic scaling of local second-order correlations with increasing interaction strength agree with the predictions of recent generalized thermodynamic Bethe-ansatz calculations. By contrast, third-order correlations obtained within our approach exhibit a markedly different power-law dependence on the interaction strength as the Tonks-Girardeau limit of infinitely strong interactions is approached.Comment: 19 pages, 10 figures. v3: Final version. Typos fixed, and other minor change

Operative versus nonoperative treatment of acute Achilles tendon ruptures: A pilot economic decision analysis

Background: The operative treatment of Achilles tendon ruptures has been associated with lower rerupture rates and better function but also a risk of surgery-related complications compared with nonoperative treatment, which may provide improved outcomes with accelerated rehabilitation protocols. However, economic decision analyses integrating the updated costs of both treatment options are limited in the literature. Purpose: To compare the cost-effectiveness of operative and nonoperative treatment of acute Achilles tendon tears. Study Design: Economic and decision analysis; Level of evidence, 2. Methods: An economic decision model was built to assess the cost-utility ratio (CUR) of open primary repair versus nonoperative treatment for acute Achilles tendon ruptures, based on direct costs from the practices of sports medicine and foot and ankle surgeons at a single tertiary academic center, with published outcome probabilities and patient utility data. Multiway sensitivity analyses were performed to reflect the range of data. Results: Nonoperative treatment was more cost-effective in the average scenario (nonoperative CUR, US$520; operative CUR, US$1995), but crossover occurred during the sensitivity analysis (nonoperative CUR range, US$224-US$2079; operative CUR range, US$789-US$8380). Operative treatment cost an extra average marginal CUR of US$1475 compared with nonoperative treatment, assuming uneventful healing in both treatment arms. The sensitivity analysis demonstrated a decreased marginal CUR of operative treatment when the outcome utility was maximized, and rerupture rates were minimized compared with nonoperative treatment. Conclusion: Nonoperative treatment was more cost-effective in average scenarios. Crossover indicated that open primary repair would be favorable for maximized outcome utility, such as that for young athletes or heavy laborers. The treatment decision for acute Achilles tendon ruptures should be individualized. These pilot results provide inferences for further longitudinal analyses incorporating future clinical evidence