Inelastic neutron scattering signal from deconfined spinons in a fractionalized antiferromagnet

We calculate the contribution of deconfined spinons to inelastic neutron scattering (INS) in the fractionalized antiferromagnet (AF*), introduced elsewhere. We find that the presence of free spin-1/2 charge-less excitations leads to a continuum INS signal above the Neel gap. This signal is found above and in addition to the usual spin-1 magnon signal, which to lowest order is the same as in the more conventional confined antiferromagnet. We calculate the relative weights of these two signals and find that the spinons contribute to the longitudinal response, where the magnon signal is absent to lowest order. Possible higher-order effects of interactions between magnons and spinons in the AF* phase are also discussed.Comment: 9 page

The twisted fourth moment of the Riemann zeta function

We compute the asymptotics of the fourth moment of the Riemann zeta function times an arbitrary Dirichlet polynomial of length $T^{{1/11} - \epsilon}$Comment: 28 pages. v2: added reference

Radio to Gamma-Ray Emission from Shell-type Supernova Remnants: Predictions from Non-linear Shock Acceleration Models

Supernova remnants (SNRs) are widely believed to be the principal source of galactic cosmic rays. Such energetic particles can produce gamma-rays and lower energy photons via interactions with the ambient plasma. In this paper, we present results from a Monte Carlo simulation of non-linear shock structure and acceleration coupled with photon emission in shell-like SNRs. These non-linearities are a by-product of the dynamical influence of the accelerated cosmic rays on the shocked plasma and result in distributions of cosmic rays which deviate from pure power-laws. Such deviations are crucial to acceleration efficiency and spectral considerations, producing GeV/TeV intensity ratios that are quite different from test particle predictions. The Sedov scaling solution for SNR expansions is used to estimate important shock parameters for input into the Monte Carlo simulation. We calculate ion and electron distributions that spawn neutral pion decay, bremsstrahlung, inverse Compton, and synchrotron emission, yielding complete photon spectra from radio frequencies to gamma-ray energies. The cessation of acceleration caused by the spatial and temporal limitations of the expanding SNR shell in moderately dense interstellar regions can yield spectral cutoffs in the TeV energy range; these are consistent with Whipple's TeV upper limits on unidentified EGRET sources. Supernova remnants in lower density environments generate higher energy cosmic rays that produce predominantly inverse Compton emission at super-TeV energies; such sources will generally be gamma-ray dim at GeV energies.Comment: 62 pages, AASTeX format, including 1 table and 11 figures, accepted for publication in The Astrophysical Journal (Vol 513, March 1, 1999

Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies.

The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional question: "For what cost and effectiveness values would adding adjunct-based treatment strategies to the standard of care for venomous snakebites be cost-effective?" We modeled the cost and performance of potential interventions (e.g., pharmacologic or preventive) used adjunctively with antivenom and supportive care for the treatment of snakebite. Because these potential interventions are theoretical, we used a threshold cost-effectiveness approach to explore this forward-looking concept. We examined economic parameters at which these interventions could be cost-effective or even cost saving. A threshold analysis was used to examine the addition of new interventions to the standard of care. Incremental cost-effectiveness ratios were used to compare treatment strategies. One-way, scenario, and probabilistic sensitivity analyses were conducted to analyze parameter uncertainty and define cost and effectiveness thresholds. Our results suggest that even a 3% reduction in severe cases due to an adjunct strategy is likely to reduce the cost of overall treatment and have the greatest impact on cost-effectiveness. In this model, for example, an investment of $10 of intervention that reduces the incidence of severe cases by 3$75 per individual. These findings illustrate the striking degree to which an adjunct intervention could improve patient outcomes and be cost-effective or even cost saving

Environmental Hazard of Excess Dunder on Agricultural Land

The use of high biochemical oxygen demand (BOD) organic waste on farming land offers two resource recovery opportunities, first nutrient for plant production and secondly organic matter for soil health. One such waste, dunder from yeast production was tested for its impact on irrigated lucerne hay production. A randomised complete block trial with five treatments (0, 8, 24, 48, 96 L dunder m-2)and three replications was used to test the impact of dunder on total dry matter production. The trial showed that the lower rates of 8 and 24 L m-2 of dunder was not significantly different to the control (0) while the high rates of 48 and 96 L m-2 significantly reduced total dry matter. This was significant as it identified limits to dunder application rate. However, more importantly, the trial showed that site characteristics and agronomic management had greater impact than the dunder alone on the plant production. In this trial a sodium hazard not related to the dunder significantly added to the reduction of dry matter. The results show that the assessment of dunder and other similar wastes for land application must include both the direct and indirect site related consequences of application to agricultural land

Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids

Ionic liquids are salts used in a variety of industrial processes, and being relatively non-volatile, are proposed as environmentally-friendly replacements for existing volatile liquids. Methylimidazolium ionic liquids resist complete degradation in the environment, likely because the imidazolium moiety does not exist naturally in biological systems. However, there is limited data available regarding their mammalian effects in vivo. This study aimed to examine the effects of exposing mice separately to 2 different methylimidazolium ionic liquids (BMI and M8OI) through their addition to drinking water. Potential effects on key target organs-the liver and kidney-were examined, as well as the gut microbiome. Adult male mice were exposed to drinking water containing ionic liquids at a concentration of 440 mg/L for 18 weeks prior to examination of tissues, serum, urine and the gut microbiome. Histopathology was performed on tissues and clinical chemistry on serum for biomarkers of hepatic and renal injury. Bacterial DNA was isolated from the gut contents and subjected to targeted 16S rRNA sequencing. Mild hepatic and renal effects were limited to glycogen depletion and mild degenerative changes respectively. No hepatic or renal adverse effects were observed. In contrast, ionic liquid exposure altered gut microbial composition but not overall alpha diversity. Proportional abundance of Lachnospiraceae, Clostridia and Coriobacteriaceae spp. were significantly greater in ionic liquid-exposed mice, as were predicted KEGG functional pathways associated with xenobiotic and amino acid metabolism. Exposure to ionic liquids via drinking water therefore resulted in marked changes in the gut microbiome in mice prior to any overt pathological effects in target organs. Ionic liquids may be an emerging risk to health through their potential effects on the gut microbiome, which is implicated in the causes and/or severity of an array of chronic disease in humans

Improved Constraints on the Acceleration History of the Universe and the Properties of the Dark Energy

We extend and apply a model-independent analysis method developed earlier by Daly & Djorgovski to new samples of supernova standard candles, radio galaxy and cluster standard rulers, and use it to constrain physical properties of the dark energy as functions of redshift. Similar results are obtained for the radio galaxy and supernova data sets. The first and second derivatives of the distance are compared directly with predictions in a standard model based on General Relativity. The good agreement indicates that General Relativity provides an accurate description of the data on look-back time scales of about ten billion years. The first and second derivatives are combined to obtain the acceleration parameter, assuming only the validity of the Robertson-Walker metric, independent of a theory of gravity and of the physical nature of the dark energy. The acceleration of the universe at the current epoch is indicated by the analysis. The effect of non-zero space curvature on q(z) is explored. We solve for the pressure, energy density, equation of state, and potential and kinetic energy of the dark energy as functions of redshift assuming that General Relativity is the correct theory of gravity, and the results indicate that a cosmological constant in a spatially flat universe provides a good description of each of these quantities over the redshift range from zero to about one. We define a new function, the dark energy indicator, in terms of the first and second derivatives of the coordinate distance and show how this can be used to measure deviations of w from -1 and to obtain a new and independent measure of Omega.Comment: 46 pages, submitted for publicatio