A numerical test of the Y-system in the small size limit of the SU(2)x SU(2) Principal Chiral Model

Recently, Kazakov, Gromov and Vieira applied the discrete Hirota dynamics to study the finite size spectra of integrable two dimensional quantum field theories. The method has been tested from large values of the size L down to moderate values using the SU(2) x SU(2) principal chiral model as a theoretical laboratory. We continue the numerical analysis of the proposed non-linear integral equations showing that the deep ultraviolet region L -> 0 is numerically accessible. To this aim, we introduce a relaxed iterative algorithm for the numerical computation of the low-lying part of the spectrum in the U(1) sector. We discuss in details the systematic errors involved in the computation. When a comparison is possible, full agreement is found with previous TBA computations.Comment: 28 pages, 24 figure

Non-classical correlations in non-Markovian continuous variable systems

We consider two identical and non-interacting harmonic oscillators coupled to either two independent bosonic baths or to a common bosonic bath. Under the only assumption of weak coupling, we analyze in details the non-Markovian short time-scale evolution of intensity correlations, entanglement and quantum discord for initial two-mode squeezed-thermal vacuum states. In the independent reservoirs case we observe the detrimental effect of the environment for all these quantities and we establish a hierarchy for their robustness against the environmental noise. In the common reservoir case, for initial uncorrelated states, we find that only quantum discord can be created via interaction with the bath, while entanglement and sub shot noise intensity correlations remain absent.Comment: 10 pages, 5 figure

Sudakov expansions at one loop and beyond for charged scalar and fermion pair production in SUSY models at future Linear Colliders

We consider the high energy behaviour of the amplitudes for pair production of charged leptons, quarks, Higgs bosons, sleptons, squarks and charginos at lepton colliders. We give the general expressions of the leading quadratic and subleading linear logarithms that appear at the one loop level, and derive the corresponding resummed expansions to \underline{subleading} logarithmic order accuracy. Under the assumption of a relatively light SUSY scenario and choosing the MSSM as a specific model, we compare the predictions of the one-loop and of the resummed expansions at variable energy. We show that the two predictions are very close in the one TeV regime, but drastically differ in the few ($2,3$) TeV range.Comment: 43 pages, 13 Encapsulated PostScript figure

Dominant BIN1-related centronuclear myopathy (CNM) revealed by lower limb myalgia and moderate CK elevation

We report a BIN1-related CNM family with unusual clinical phenotype. The proband, a 56-year-old man suffered of lower limbs myalgia since the age of 52. Clinical examination showed short stature, mild symmetric eyelid ptosis without ophthalmoplegia, scapular winging and Achilles tendon retraction. A muscle weakness was not noted. CK levels were up to 350 UI/L. Deltoid muscle biopsy showed nuclear centralization and clustering, deep sarcolemmal invaginations and type 1 fiber hypotrophy. Whole body MRI revealed fatty infiltration of posterior legs compartments, lumbar paraspinal and serratus muscles. Myotonic dystrophy type1 and 2, Pompe disease and MTM1 and DNM2-related CNM were ruled out. By sequencing BIN1, we identified a heterozygous pathogenic mutation [c.107C > A (p.A36E)], and we demonstrate that the mutation strongly impairs the membrane tubulation property of the protein. One affected sister carried the same mutation. Her clinical examination and muscle MRI revealed a similar phenotype. Our findings expand the clinical and genetic spectrum of the autosomal dominant CNM associated with BIN1 mutations

The Momentum Amplituhedron

In this paper we define a new object, the momentum amplituhedron, which is the long sought-after positive geometry for tree-level scattering amplitudes in N = 4 super Yang-Mills theory in spinor helicity space. Inspired by the construction of the ordinary amplituhedron, we introduce bosonized spinor helicity variables to represent our external kinematical data, and restrict them to a particular positive region. The momentum amplituhedron M n,k is then the image of the positive Grassmannian via a map determined by such kinematics. The scattering amplitudes are extracted from the canonical form with logarithmic singularities on the boundaries of this geometry.Peer reviewedFinal Published versio

Mercury and selenium binding biomolecules in terrestrial mammals (Cervus elaphus and Sus scrofa) from a mercury exposed area

Acknowledgements The authors are grateful to Junta de Comunidades de Castilla-La Mancha (PCC-05-004-2, PAI06-0094, PCI-08-0096, PEII09-0032-5329) and the Ministerio de Economía y Competitividad (CTQ2013-48411-P) for financial support. M.J. Patiño Ropero acknowledges the Junta de Comunidades de Castilla-La Mancha for her PhD. fellowship.Peer reviewedPostprin

Investigation of resonant and transient phenomena in Josephson junction flux qubits

We present an analytical and computational study of resonances and transient responses in a classical Josephson junction system. A theoretical basis for resonances in a superconducting loop with three junctions is presented, outlining both the direct relationship between the dynamics of single- and multi-junction systems, and the direct relationships between observations of the classical counterparts to Rabi oscillations, Ramsey fringes, and spin echo oscillations in this class of systems. We show simulations data along with analytical analyses of the classical model, and the results are related to previously reported experiments conducted on three junction loops. We further investigate the effect of off-resonant microwave perturbations to, e.g., the Rabi-type response of the Josephson system, and we relate this response back to the nonlinear and multi-valued resonance behavior previously reported for a single Josephson junction. The close relationships between single and multi-junction behavior demonstrates the underlying dynamical mechanism for a whole class of classical counterparts to expected quantum mechanical observations in a variety of systems; namely the resonant and transient behavior of a particle in an anharmonic potential well with subsequent escape.Comment: 11 pages, seven figure

Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity

G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in telomeres, oncogene promoters and coding regions of the human chromosome. In particular, they have been proposed to be directly involved in gene regulation at the level of transcription. Because the HIV-1 Nef protein is a fundamental factor for efficient viral replication, infectivity and pathogenesis in vitro and in vivo, we investigated G-quadruplex formation in the HIV-1 nef gene to assess the potential for viral inhibition through G-quadruplex stabilization. A comprehensive computational analysis of the nef coding region of available strains showed the presence of three conserved sequences that were uniquely clustered. Biophysical testing proved that G-quadruplex conformations were efficiently stabilized or induced by G-quadruplex ligands in all three sequences. Upon incubation with a G-quadruplex ligand, Nef expression was reduced in a reporter gene assay and Nef-dependent enhancement of HIV-1 infectivity was significantly repressed in an antiviral assay. These data constitute the first evidence of the possibility to regulate HIV-1 gene expression and infectivity through G-quadruplex targeting and therefore open a new avenue for viral treatment. © 2013 Perrone et al

Universal Finite Size Scaling Functions in the 3D Ising Spin Glass

We study the three-dimensional Edwards-Anderson model with binary interactions by Monte Carlo simulations. Direct evidence of finite-size scaling is provided, and the universal finite-size scaling functions are determined. Monte Carlo data are extrapolated to infinite volume with an iterative procedure up to correlation lengths xi \approx 140. The infinite volume data are consistent with a conventional power law singularity at finite temperature Tc. Taking into account corrections to scaling, we find Tc = 1.156 +/- 0.015, nu = 1.8 +/- 0.2 and eta = -0.26 +/- 0.04. The data are also consistent with an exponential singularity at finite Tc, but not with an exponential singularity at zero temperature.Comment: 4 pages, Revtex, 4 postscript figures include

Adiabatic and non-adiabatic phonon dispersion in a Wannier function approach

We develop a first-principles scheme to calculate adiabatic and non-adiabatic phonon frequencies in the full Brillouin zone. The method relies on the variational properties of a force-constants functional with respect to the first-order perturbation of the electronic charge density and on the localization of the deformation potential in the Wannier function basis. This allows for calculation of phonon dispersion curves free from convergence issues related to Brillouin zone sampling. In addition our approach justify the use of the static screened potential in the calculation of the phonon linewidth due to decay in electron-hole pairs. We apply the method to the calculation of the phonon dispersion and electron-phonon coupling in MgB$_2$ and CaC$_6$. In both compounds we demonstrate the occurrence of several Kohn anomalies, absent in previous calculations, that are manifest only after careful electron and phonon momentum integration. In MgB$_2$, the presence of Kohn anomalies on the E$_{2g}$ branches improves the agreement with measured phonon spectra and affects the position of the main peak in the Eliashberg function. In CaC$_6$ we show that the non-adiabatic effects on in-plane carbon vibrations are not localized at zone center but are sizable throughout the full Brillouin zone. Our method opens new perspectives in large-scale first-principles calculations of dynamical properties and electron-phonon interaction.Comment: 18 pages, 8 figure