Reimagining the Digital Monograph: Design Thinking to Build New Tools for Researchers, A JSTOR Labs Report

Scholarly books are increasingly available in digital form, but the online interfaces for using these books often allow only for the browsing of PDF files. JSTOR Labs, an experimental product-development group within the not-for-profit digital library JSTOR, undertook an ideation and design process to develop new and different ways of showing scholarly books online, with the goal that this new viewing interface should be relatively simple and inexpensive to implement for any scholarly book that is already available in PDF form. This paper documents that design process, including the recommendations of a working group of scholars, publishers, and librarians convened by JSTOR Labs and the Columbia University Libraries in October 2016. The prototype monograph viewer developed through this process—called “Topicgraph”—is described herein and is freely available online at https://labs.jstor.org/topicgraph

National Program for Genetic Improvement of Feed Efficiency in Beef Cattle

Our goal is to sustainably reduce feed resources required to produce beef via the rapid development and deployment of novel nutritional, genomic and genetic improvement technologies. We will strengthen the international competitiveness of US agriculture and enable increased food production by increasing the animal protein produced without additional feed inputs and with a reduced greenhouse gas footprint

Iowa Cattle Feeding - Beyond the Margins

Feeding cattle is an important farming enterprise and a vital sector of Iowa's economy. This publication looks at competitive advantages that Iowa cattle feedlots hold, and the opportunities available to producers to navigate through market challenges. Cattle feeding profits, managing price risk and the overall economic environment are all discussed.</p

Iowa Cattle Feeding - Beyond the Margins

Feeding cattle is an important farming enterprise and a vital sector of Iowa\u27s economy. This publication looks at competitive advantages that Iowa cattle feedlots hold, and the opportunities available to producers to navigate through market challenges. Cattle feeding profits, managing price risk and the overall economic environment are all discussed

LETTER TO THE EDITOR Mutations in progranulin explain atypical phenotypes with variants in MAPT

doi:10.1093/brain/awl289 Mutations in presenilin-1 (PSEN1) cause autosomal dominant Alzheimer’s disease and mutations in MAPT cause the familial tauopathy Frontotemporal dementia linked to chromosome 17 (FTDP-17). However, there have been reports of mutations in PSEN1 and MAPT associated with cases of FTD with ubiquitin-positive tau-negative inclusion pathology. Here, we demonstrate that the MAPT variants are almost certainly rare benign polymorphisms as all of these cases harbour mutations in Progranulin (PGRN). Mutations in PGRN were recently shown to cause ubiquitin-positive FTDP-17