Development of a glue-free bimorph mirror for use in vacuum chambers

PZT (lead zirconate titanate)-glued bimorph deformable mirrors are widely used in hard X-ray regimes; however, they have not yet been used in soft X-ray regimes because they are less compatible for usage under high vacuum. In this study, we developed a glue-free bimorph deformable mirror, in which silver nano-particles were employed to bond PZT actuators to mirror substrates. Under an appropriate bonding condition, the bonding layer was confirmed to be uniform and the mirror's bending characteristics were demonstrated to be sufficiently stable; its gas emission rate was also shown to be acceptable. Piezo responses before and after additional heating at 200 °C showed the thermal stability of its bonding and bending properties.Yoshio Ichii, Hiromi Okada, Hiroki Nakamori, Akihiko Ueda, Hiroyuki Yamaguchi, Satoshi Matsuyama, and Kazuto Yamauchi, "Development of a glue-free bimorph mirror for use in vacuum chambers", Review of Scientific Instruments 90, 021702 (2019), https://doi.org/10.1063/1.5066105

Utility of 19-Hydroxycholesterol as an Internal Standard Compound for the Quantitative Determination of Sterols Using Capillary Gas Chromatograph

Gas chromatography is able to detect many kinds of sterols simultaneously. In order to identify and estimate accurately many kinds of sterols in biological samples by gas chromatography, it is indispensable to add an internal standard compound into the analytical samples prior to the analysis. However, there is no report on a suitable internal standard compound for the determination of sterols. In this study, 19-hydroxycholesterol was proved to be a suitable internal standard compound for simultaneous and quantitative determination of several sterols in various analytical samples by capillary gas chromatography, including the quantitative determination of β-cholestanol in the human plasma. Moreover, the excellent condition of gas chromatographic analysis for quantitative determination of several sterols in various analytical samples was found

Distribution and behavior of bottom water in Tokyo Bay in summer : Role of wind on outflow of poor oxygen water

東京水産大学練習船東京水産大学環境システム学講座東京水産大学練習船東京水産大学環境システム学講座東京水産大学練習船東京水産大学環境システム学講

Innovative design of bone quality-targeted intervertebral spacer: accelerated functional fusion guiding oriented collagen and apatite microstructure without autologous bone graft

BACKGROUND CONTEXT: Although autologous bone grafting is widely considered as an ideal source for interbody fusion, it still carries a risk of nonunion. The influence of the intervertebral device should not be overlooked. Requirements for artificial spinal devices are to join the vertebrae together and recover the original function of the spine rapidly. Ordered mineralization of apatite crystals on collagen accelerates bone functionalization during the healing process. Particularly, the stable spinal function requires the ingrowth of an ordered collagen and apatite matrix which mimics the intact intervertebral microstructure. This collagen and apatite ordering is imperative for functional bone regeneration, which has not been achieved using classical autologous grafting. PURPOSE: We developed an intervertebral body device to achieve high stability between the host bone and synthesized bone by controlling the ordered collagen and apatite microstructure. STUDY DESIGN: This was an in vivo animal study. METHODS: Intervertebral spacers with a through-pore grooved surface structure, referred to as a honeycomb tree structure, were produced using metal 3D printing. These spacers were implanted into normal sheep at the L2–L3 or L4–L5 disc levels. As a control group, grafting autologous bone was embedded. The mechanical integrity of the spacer/bone interface was evaluated through push-out tests. RESULTS: The spacer with honeycomb tree structure induced anisotropic trabecular bone growth with textured collagen and apatite orientation in the through-pore and groove directions. The push-out load of the spacer was significantly higher than that of the conventional autologous graft spacer. Moreover, the load was significantly correlated with the anisotropic texture of the newly formed bone matrix. CONCLUSIONS: The developed intervertebral spacer guided the regenerated bone matrix orientation of collagen and apatite, resulting in greater strength at the spacer/host bone interface than that obtained using a conventional gold-standard autologous bone graft. CLINICAL SIGNIFICANCE: Our results provide a foundation for designing future spacers for interbody fusion in human.Matsugaki A., Ito M., Kobayashi Y., et al. Innovative design of bone quality-targeted intervertebral spacer: accelerated functional fusion guiding oriented collagen and apatite microstructure without autologous bone graft. Spine Journal 23, 609 (2023); https://doi.org/10.1016/j.spinee.2022.12.011

Latitudinal variation of vertical eddy diffusivity estimated from the distribution of overturns in the western part of the south Pacific Ocean

東京水産大学海洋環境学科東京水産大学海洋環境学科東京水産大学海洋環境学科東京水産大学大学院理学系研究科東京水産大学練習船東京水産大学練習船東京水産大学練習船東京水産大学練習船東京水産大学練習船東京水産大学海洋環境学