Annotation and curation of human genomic variations: an ELIXIR Implementation Study

Background: ELIXIR is an intergovernmental organization, primarily based around European countries, established to host life science resources, including databases, software tools, training material and cloud storage for the scientific community under a single infrastructure. Methods: In 2018, ELIXIR commissioned an international survey on the usage of databases and tools for annotating and curating human genomic variants with the aim of improving ELIXIR resources. The 27-question survey was made available on-line between September and December 2018 to rank the importance and explore the usage and limitations of a wide range of databases and tools for annotating and curating human genomic variants, including resources specific for next generation sequencing, research into mitochondria and protein structure. Results: Eighteen countries participated in the survey and a total of 92 questionnaires were collected and analysed. Most respondents (89%, n=82) were from academia or a research environment. 51% (n=47) of respondents gave answers on behalf of a small research group (10 people). The survey showed that the scientific community considers several resources supported by ELIXIR crucial or very important. Moreover, it showed that the work done by ELIXIR is greatly valued. In particular, most respondents acknowledged the importance of key features and benefits promoted by ELIXIR, such as the verified scientific quality and maintenance of ELIXIR-approved resources. Conclusions ELIXIR is a "one-stop-shop" that helps researchers identify the most suitable, robust and well-maintained bioinformatics resources for delivering their research tasks

Dimensioning of electrical installations : calculation softwares examined

This thesis is an examination of calculation softwares for the dimensioning of electrical installations. The thesis is done in cooperation with Vaasa Engineering Oy. The goal is to help the employer find a calculation software that is suitable for their needs. First the fundamental theory concerning the subject is dealt with. A short description of how the softwares are utilized in project planning links the theory to a practical usage of calculation softwares. These are presented from the angle of plant calculation procedures. After the presentation the calculation softwares are summarized in an evaluation of benefits and drawbacks. The result is a recommendation of which calculation software the employer should use for dimensioning electrical installations. The thesis is concluded with a short conclusion and discussion.Detta examensarbete är en undersökning av beräkningsprogram för dimensionering av elanläggningar. Examensarbetet är gjort i samarbete med Vaasa Engineering Oy. Målet är att hjälpa uppdragsgivaren med att hitta ett beräkningsprogram som är lämpligt för deras behov. Först behandlas den grundläggande teorin gällande ämnet. En kort förklaring av hur dessa program kan utnyttjas inom projektplanering länkar teorin till praktisk användning av beräkningsprogram. Dessa program presenteras ur synvinkeln tillvägagångssätt för beräkning av elanläggningar. Efter presentationen sammanfattas beräkningsprogrammen i en utvärdering av för- och nackdelar. Resultatet är en rekommendation av vilket beräkningsprogram uppdragsgivaren borde använda för dimensionering av elanläggningar. Examensarbetet avslutas med en kort sammanfattning samt diskussion